Pneumonitis as a side effect of breast cancer treatment: T-DXd and/or SBRT?

Breast cancer that overexpresses the human epidermal growth factor receptor 2 (HER2) is considered to be HER2-positive. The novel HER2- directed antibody drug conjugate, trastuzumab deruxtecan (T-DXd), is formed by covalently joining the monoclonal antibody trastuzumab with the topoisomerase I inhibitor deruxtecan. It exhibits significant anti-tumor activity in previously overtreated patients

Cryptosporidiosis; Is it „reserved“ only for the immunocompromised?

Cryptosporidium parvum is an intracellular parasite that infects gastrointestinal epitheli-um, especially in immunocompromised individuals, causing severe, life-threatening diar-rhea. It is usually transmitted through the consumption of contaminated water and food. Rarely, infection can occur in immunocompetent patients who can either be asymptomatic or present with gastrointestinal symptoms (diarrhea, abdominal pain, weight loss)