10 research outputs found
Electromagnetic Form Factors of the SU(3) Octet Baryons in the semibosonized SU(3) Nambu-Jona-Lasinio Model
The electromagnetic form factors of the SU(3) octet baryons are investigated
in the semibosonized SU(3) Nambu--Jona-Lasinio model (chiral quark-soliton
model). The rotational and strange quark mass corrections in linear
order are taken into account. The electromagnetic charge radii of the nucleon
and magnetic moments are also evaluated. It turns out that the model is in a
remarkable good agreement with the experimental data.Comment: RevTex is used. 37 pages. The final version to appear in Phys. Rev.
D. 13 figures are include
Transcription Profiling of Candida albicans Cells Undergoing the Yeast-to-Hyphal Transition
The ability of the pathogenic fungus Candida albicans to switch from a yeast to a hyphal morphology in response to external signals is implicated in its pathogenicity. We used glass DNA microarrays to investigate the transcription profiles of 6333 predicted ORFs in cells undergoing this transition and their responses to changes in temperature and culture medium. We have identified several genes whose transcriptional profiles are similar to those of known virulence factors that are modulated by the switch to hyphal growth caused by addition of serum and a 37°C growth temperature. Time course analysis of this transition identified transcripts that are induced before germ tube initiation and shut off later in the developmental process. A strain deleted for the Efg1p and Cph1p transcription factors is defective in hyphae formation, and its response to serum and increased temperature is almost identical to the response of a wild-type strain grown at 37°C in the absence of serum. Thus Efg1p and Cph1p are needed for the activation of the transcriptional program that is induced by the presence of serum