988 research outputs found
The power and statistical behaviour of allele-sharing statistics when applied to models with two disease loci
We have evaluated the power for detecting a common trait determined by two loci, using seven statistics, of which five are implemented in the computer program SimWalk2, and two are implemented in GENEHUNTER. Unlike most previous reports which involve evaluations of the power of allele-sharing statistics for a single disease locus, we have used a simulated data set of general pedigrees in which a two-locus disease is segregating and evaluated several nonparametric linkage statistics implemented in the two programs. We found that the power for detecting linkage using the S(all) statistic in GENEHUNTER (GH, version 2.1), implemented as statistic E in SimWalk2 (version 2.82), is different in the two. The P values associated with statistic E output by SimWalk2 are consistently more conservative than those from GENEHUNTER except when the underlying model includes heterogeneity at a level of 50% where the P values output are very comparable. On the other hand, when the thresholds are determined empirically under the null hypothesis, S(all) in GENEHUNTER and statistic E have similar powe
A double neutron star merger origin for the cosmological relativistic fading source PTF11agg?
The Palomar Transient Factory (PTF) team recently reported the discovery of a
rapidly fading optical transient source, PTF11agg. A long-lived scintillating
radio counterpart was identified, but the search for a high energy counterpart
showed negative results. The PTF team speculated that PTF11agg may represent a
new class of relativistic outbursts. Here we suggest that a neutron star
(NS)-NS merger system with a supra-massive magnetar central engine could be a
possible source to power such a transient, if our line of sight is not on the
jet axis direction of the system. These systems are also top candidates for
gravitational wave sources to be detected in the advanced LIGO/Virgo era. We
find that the PTF11agg data could be explained well with such a model,
suggesting that at least some gravitational wave bursts due to NS-NS mergers
may be associated with such a bright electromagnetic counterpart without a
\gamma-ray trigger.Comment: Accepted for publication in ApJ Letter
Synchronization of fractional chaotic complex networks with delays
summary:The synchronization of fractional-order complex networks with delay is investigated in this paper. By constructing a novel Lyapunov-Krasovskii function and taking integer derivative instead of fractional derivative of the function, a sufficient criterion is obtained in the form of linear matrix inequalities to realize synchronizing complex dynamical networks. Finally, a numerical example is shown to illustrate the feasibility and effectiveness of the proposed method
Quantum Manifestations of Graphene Edge Stress and Edge Instability: A First-Principles Study
We have performed first-principles calculations of graphene edge stresses,
which display two interesting quantum manifestations absent from the classical
interpretation: the armchair edge stress oscillates with a nanoribbon width,
and the zigzag edge stress is noticeably reduced by spin polarization. Such
quantum stress effects in turn manifest in mechanical edge twisting and warping
instability, showing features not captured by empirical potentials or continuum
theory. Edge adsorption of H and Stone-Wales reconstruction are shown to
provide alternative mechanisms in relieving the edge compression and hence to
stabilize the planar edge structure.Comment: 5figure
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