Porin new light onto chromatin and nuclear organization

The capture of associations between chromatin and nuclear pore complexes throws new light on chromosome organization in the nucleus

A condensed view of chromatin during T cell development

The mechanisms limiting clonal T-cell expansion in response to cytokines to cells that have recognised cognate antigen via their T-cell receptor are incompletely understood. A study by Rawlings et al identifies one such mechanism that functions, unexpectedly, through chromatin compaction and involves a subunit of condensin — a complex better known for restructuring chromosomes in mitosis