Perception of Secondary School Teachers Towards the Transformational Leadership for Teachers' Effectiveness

The main aim of this study was to identify the perception of secondary school teachers towards transformational leadership styles among their principals for teachers' effectiveness. The transformational leadership factors consist of idealised influence attribute and behaviour, intellectual stimulation, individualised consideration and inspirational motivation. The study was conducted in ten secondary schools in the Kuala Pilah, Jelebu and Jempol district. A total of 235 teachers were selected by using a simple random sampling method. Statistical analysis such as descriptive, percentage, means scores and Pearson correlation test were carried out. The findings revealed that the principals 'sometimes' exhibited idealised influence attribute (X = 2.35) and behaviour, 'sometimes' provided inspirational motivation (X=2.59), and 'sometimes' (X=2.59) utilised intellectual stimulation in executing tasks to teachers. The results also proved principals in KPJJ district 'once in a while' give individualised consideration (X= 1.89) to their teachers. Correlational analysis indicated that principals' idealised influence attribute, idealised influence behaviour, inspirational motivation, intellectual stimulation and individualised consideration were related to teachers' effectiveness. This means that the relationship between the four factors of transformational leadership and teachers' effectiveness were positive and moderate. The higher the principals displayed transformational leadership styles the higher will be teachers' effectiveness in their performance

Production of Ethanol by fermentation process by using Yeast Saccharomyces cerevisae

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Rapunzel syndrome and gastric Peutz Jeghers (hamartomatous) polyps: case report

Rapunzel syndrome is an extremely rare complication of a trichobezoar. These females have a history of trichophagia and trichotillomania. Peutz Jeghers syndrome (PJS) is an uncommon autosomal dominant syndrome with a variable to high penetrance that leads to the development of the polyps within the gastrointestinal mucosa. This case report of a 25-year-old deaf and dumb female presented with pain and lump in upper abdomen, vomiting, nausea, loss of appetite, loss of weight. An exploratory laparotomy with anterior gastrotomy was performed and a giant trichobezoar with tail extending into the duodenum was removed. There were multiple polyps in the lower stomach excised. Histopathology reports showed Peutz Jeghers (hamartomatous polyps). She recovered well and was discharged on the 10th day. Patient was advised regular follow up

A COMPARATIVE RESEARCH TO EVALUATE MVA (MANUAL VACUUM ASPIRATION) AND MEDICAL TREATMENT TO MANAGE MISSED MISCARRIAGE (FIRST TRIMESTER)

Objective: The objective of this research is to evaluate and contrast the medical treatment and MVA (Manual Vacuum Aspiration) for managing the miscarriage in the 1st trimester. Material and Methods: This comparative research was conducted at Sir Ganga Ram Hospital, Lahore (August 2017 to March 2018). This research consists of a total of 92 cases of patients having a gestation age of less than twelve (12) weeks of missed abortion in the first trimester. Two groups were made of the patients: group A was treated with MVA whereas group B was treated medically and their effectiveness was evaluated. Results: The patients’ mean age was (29.77 ± 6.786) years in which group A patients’ mean age was (30.61 ± 6.754) years while group B patients’ mean age was (28.93 ± 6.787) years. The gestational mean age was (5.87 ± 3.592) weeks in which group A gestational mean age was (6.09 ± 3.699) weeks while group B gestational mean age was (5.65 ± 3.510) weeks. In group A patients, the effectiveness of treatment was 91.30% (42 out of 46 patients) while in the group B patients, the effectiveness of the treatment was 69.57% (32 out of 46 patients). The rate of effectiveness of cure for group A was considerably greater than Group B i.e., 91.30% as compared to 69.57%, having (p=0.009). Conclusion: The outcome of this research proved that MVA is a far more useful modality of treatment than medical treatment i.e., misoprostol intravaginally, as the rate of effectiveness of cure was considerably greater for the group of MVA than the group which was treated medically and it was especially true in the group of patients with older ages. Keywords: Evacuation and Dilatation, Incomplete Abortion and Manual Vacuum Aspiration

Incivility Within and Beyond Classrooms: Exploring the Perceptions of Targets, Instigators, and Observers

This study aimed at understanding the perceptions of female students who had experienced or witnessed incivility by faculty, and instigated incivility in or out of the classroom and how it affected them. Through the application of a phenomenological and qualitative approach, data were collected from eight (8) female business administration students from public sector universities of Quetta, Pakistan. The findings of the study revealed that female students experienced and witnessed faculty incivility within and beyond the classrooms, which included harassment, character assassination, and humiliation characterized as intense behaviors of faculty. These encounters of faculty incivility resulted in psychological distress like depression, interrupted sleeping patterns, and fear. Furthermore, the findings concerning instigated incivility exhibited that those female students who misbehaved with their instructors were distressed and wanted to quit their studies. The results of this study would be helpful for the university administration to develop policies to combat incivility in educational institutions

Arousal Safety Leading to Purchase Intention; The Role of Moderating and Mediating Variables in Structural Model

The effect of arousal safety has been analyzed on purchase intention, then attitude towards the advertisement and attitude towards the brand have been incorporated as intervening variables between the relationships. The interaction effect of self-monitoring and message arguments have also been taken in to consideration for better understanding of the consumer’s response. The data has been gathered from 206 respondents by using purposive sampling method. The research instrument was comprised of summated rating/additive scale (likert scale) and semantic differential scaling. Confirmatory Factor Analysis has been applied after the application of preliminary tests on the data. Structure Equation Modeling and moderation and mediation analysis have also been applied to test the hypotheses. Arousal safety in the advertisements shape consumers response and it proved to be a fully mediated model. Self-monitoring also probes the relationship. Message arguments haven’t had any affect as moderator, hence can be used as a focal predictor. The study is a starting point for future research to provide a coherent methodology for capturing the necessary data, processing the underlying information and evaluating the effects of arousal safety in advertisements. The study extends the field of advertising in the direction of arousal safety (Humor) effects. In comparison to previous research, empirical evidence on the arousal safety in television advertising and purchase intention in relation with moderating and mediating variables is provided

A Review on Strong Impacts of Thermal Stress on Plants Physiology, Agricultural Yield; and Timely Adaptation in Plants to Heat Stress

In this review, we checked the harsh influence of high temperature or heat stress on plant metabolism and crop yield. Plants can bear a minimum range of temperature; temperature more than this optimum range comes in the term of heat stress. Climate changes increase the number and severity of heat waves that reduced the development of plants and resulted in the death of the entire plant. Heat stress is a major stressful environment that destroys plant growth, biochemical reactions, and the yield of crops across the world. High-temperature influences many physiological and chemical reactions in plants. HS is now a big deal for crop production and the essential goal of agriculture is to maintain a high yield of crops. A plant lives in the conditions of high temperature based on its capacity to receive the HT stimulus, generate and change the signal, and then initiate physiological and biochemical changes. The plants show physiological and biochemical responses to heat the stress, is an active area of research. To deal with HT, different molecular techniques are in progress. After thoroughly reviewed of the different discoveries on plants’ responses, adaptation, and forbearance to HT at the cellular, organelles, and entire plant levels, this article described several approaches that could be taken to increase thermo- forbearance in plants

Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods: GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. Findings: Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990–2010 time period, with the greatest annualised rate of decline occurring in the 0–9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10–24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10–24 years were also in the top ten in the 25–49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50–74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. Interpretation: As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and developm nt investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve. Funding: Bill & Melinda Gates Foundation. © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licens

Effects of antibiotic resistance, drug target attainment, bacterial pathogenicity and virulence, and antibiotic access and affordability on outcomes in neonatal sepsis: an international microbiology and drug evaluation prospective substudy (BARNARDS)

Background Sepsis is a major contributor to neonatal mortality, particularly in low-income and middle-income countries (LMICs). WHO advocates ampicillin–gentamicin as first-line therapy for the management of neonatal sepsis. In the BARNARDS observational cohort study of neonatal sepsis and antimicrobial resistance in LMICs, common sepsis pathogens were characterised via whole genome sequencing (WGS) and antimicrobial resistance profiles. In this substudy of BARNARDS, we aimed to assess the use and efficacy of empirical antibiotic therapies commonly used in LMICs for neonatal sepsis. Methods In BARNARDS, consenting mother–neonates aged 0–60 days dyads were enrolled on delivery or neonatal presentation with suspected sepsis at 12 BARNARDS clinical sites in Bangladesh, Ethiopia, India, Pakistan, Nigeria, Rwanda, and South Africa. Stillborn babies were excluded from the study. Blood samples were collected from neonates presenting with clinical signs of sepsis, and WGS and minimum inhibitory concentrations for antibiotic treatment were determined for bacterial isolates from culture-confirmed sepsis. Neonatal outcome data were collected following enrolment until 60 days of life. Antibiotic usage and neonatal outcome data were assessed. Survival analyses were adjusted to take into account potential clinical confounding variables related to the birth and pathogen. Additionally, resistance profiles, pharmacokinetic–pharmacodynamic probability of target attainment, and frequency of resistance (ie, resistance defined by in-vitro growth of isolates when challenged by antibiotics) were assessed. Questionnaires on health structures and antibiotic costs evaluated accessibility and affordability. Findings Between Nov 12, 2015, and Feb 1, 2018, 36 285 neonates were enrolled into the main BARNARDS study, of whom 9874 had clinically diagnosed sepsis and 5749 had available antibiotic data. The four most commonly prescribed antibiotic combinations given to 4451 neonates (77·42%) of 5749 were ampicillin–gentamicin, ceftazidime–amikacin, piperacillin–tazobactam–amikacin, and amoxicillin clavulanate–amikacin. This dataset assessed 476 prescriptions for 442 neonates treated with one of these antibiotic combinations with WGS data (all BARNARDS countries were represented in this subset except India). Multiple pathogens were isolated, totalling 457 isolates. Reported mortality was lower for neonates treated with ceftazidime–amikacin than for neonates treated with ampicillin–gentamicin (hazard ratio [adjusted for clinical variables considered potential confounders to outcomes] 0·32, 95% CI 0·14–0·72; p=0·0060). Of 390 Gram-negative isolates, 379 (97·2%) were resistant to ampicillin and 274 (70·3%) were resistant to gentamicin. Susceptibility of Gram-negative isolates to at least one antibiotic in a treatment combination was noted in 111 (28·5%) to ampicillin–gentamicin; 286 (73·3%) to amoxicillin clavulanate–amikacin; 301 (77·2%) to ceftazidime–amikacin; and 312 (80·0%) to piperacillin–tazobactam–amikacin. A probability of target attainment of 80% or more was noted in 26 neonates (33·7% [SD 0·59]) of 78 with ampicillin–gentamicin; 15 (68·0% [3·84]) of 27 with amoxicillin clavulanate–amikacin; 93 (92·7% [0·24]) of 109 with ceftazidime–amikacin; and 70 (85·3% [0·47]) of 76 with piperacillin–tazobactam–amikacin. However, antibiotic and country effects could not be distinguished. Frequency of resistance was recorded most frequently with fosfomycin (in 78 isolates [68·4%] of 114), followed by colistin (55 isolates [57·3%] of 96), and gentamicin (62 isolates [53·0%] of 117). Sites in six of the seven countries (excluding South Africa) stated that the cost of antibiotics would influence treatment of neonatal sepsis