Evaluation of Antibacterial Activity of Tecomella undulata leaves crude Extracts

Abstract In the present study antibacterial activity of Tecomella undulata, leave

Identification of Bioactive Compounds from Peels of Punica granatum L. by GC-MS analysis

India is the second major producer of fruits and vegetables in the world. Fruits form the rich source of bioactive molecules. Phytochemical compounds can provide different health benefits and give protection against various diseases as per the literature. As a result of this, the search for new bioactive molecules with multifunctional properties have been rapidly intensified. Pomegranate known as the ‘Nature’s power fruit' and ‘Fruit of dead' is one of the oldest fruit to be cultivated. Because of high nutritional value, these fruits are consumed at a greater extent. As a result, large amount of peel waste is generated. Disposal of these waste is of major concern. Thus, in the present study, an attempt was made to bring utilization of peels by finding the bioactive compounds present in the peels and further its application in food and cosmetics. The aim of the study was to investigate the presence of different compounds from the methanolic extract of Punica granatum L. peel by GC-MS analysis

Antidiabetic activity of leaves of Anthocephalus indicus A. Rich. in alloxan induced diabetic rats

The present study aims to examine the antidiabetic potential of leaves of Anthocephalus indicus A. Rich. The aqueous extract of leaves was screened for serum glucose lowering activity. Diabetes was induced in Sprague Dawley adult male rats by intra peritoneal injection of alloxan monohydrate at 80mg/kg bw. to the rats. Aqueous leaves extract of Anthocephalus indicus A. Rich. at 400mg/kg bw was given orally to control and diabetic rats for 21 days. Blood samples taken from retro orbital plexus of rats were analysed for serum glucose level, total cholesterol, high density lipoprotein (HDL- cholesterol) and low density lipoprotein (LDL- cholesterol) as per standard kit method. The rats feed with aqueous leaves extract showed significant reduction in blood glucose, total cholesterol, triglycerides, HDL and LDL as compared to diabetic rats. Aqueous leaf extract results for antidiabetic activity were compared with standard drug glibenclamide at 10mg/kg bw. and the antidiabetic acitivity was found to be significant. Histopathological study of liver and pancreas of rats showed that alloxan caused damage in the liver cells and degeneration of pancreatic islet cells. Administration of aqueous leaves extract caused an improvement in damaged liver cells and degenerated pancreatic islet cells. Thus, Anthocephalus indicus can be considered as a good natural antidiabetic drug