15 research outputs found

    Enhanced Performance Cooperative Localization Wireless Sensor Networks Based on Received-Signal-Strength Method and ACLM

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    There has been a rise in research interest in wireless sensor networks (WSNs) due to the potential for his or her widespread use in many various areas like home automation, security, environmental monitoring, and lots more. Wireless sensor network (WSN) localization is a very important and fundamental problem that has received a great deal of attention from the WSN research community. Determining the relative coordinate of sensor nodes within the network adds way more aiming to sense data. The research community is extremely rich in proposals to deal with this challenge in WSN. This paper explores the varied techniques proposed to deal with the acquisition of location information in WSN. In the study of the research paper finding the performance in WSN and those techniques supported the energy consumption in mobile nodes in WSN, needed to implement the technique and localization accuracy (error rate) and discuss some open issues for future research. The thought behind Internet of things is that the interconnection of the Internet-enabled things or devices to every other and human to realize some common goals. WSN localization is a lively research area with tons of proposals in terms of algorithms and techniques. Centralized localization techniques estimate every sensor node's situation on a network from a central Base Station, finding absolute or relative coordinates (positioning) with or without a reference node, usually called the anchor (beacon) node. Our proposed method minimization error rate and finding the absolute position of nodes

    A curated online resource for SOX10 and pigment cell molecular genetic pathways

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    We describe the creation of a specialized web-accessible database named the Pigment Cell Gene Resource, which contains information on the genetic pathways that regulate pigment cell development and function. This manually curated database is comprised of two sections, an annotated literature section and an interactive transcriptional network diagram. Initially, this database focuses on the transcription factor SOX10, which has essential roles in pigment cell development and function, but the database has been designed with the capacity to expand in the future, allowing inclusion of many more pigmentation genes

    Photography-based taxonomy is inadequate, unnecessary, and potentially harmful for biological sciences

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    The question whether taxonomic descriptions naming new animal species without type specimen(s) deposited in collections should be accepted for publication by scientific journals and allowed by the Code has already been discussed in Zootaxa (Dubois & Nemésio 2007; Donegan 2008, 2009; Nemésio 2009a–b; Dubois 2009; Gentile & Snell 2009; Minelli 2009; Cianferoni & Bartolozzi 2016; Amorim et al. 2016). This question was again raised in a letter supported by 35 signatories published in the journal Nature (Pape et al. 2016) on 15 September 2016. On 25 September 2016, the following rebuttal (strictly limited to 300 words as per the editorial rules of Nature) was submitted to Nature, which on 18 October 2016 refused to publish it. As we think this problem is a very important one for zoological taxonomy, this text is published here exactly as submitted to Nature, followed by the list of the 493 taxonomists and collection-based researchers who signed it in the short time span from 20 September to 6 October 2016

    The effect of magnetic field dependent viscosity on thermosolutal convection in a ferromagnetic fluid saturating a porous medium,

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    The effect of the magnetic field dependent (MFD) viscosity on the thermal convection in a ferromagnetic fluid in the presence of a uniform vertical magnetic field is considered for a fluid layer in a porous medium, heated from below. For a ferromagnetic fluid layer between two free boundaries an exact solution is obtained, using a linear stability analysis. For the case of stationary convection, the medium permeability has a destabilizing effect, whereas the MFD viscosity has a stabilizing effect. In the absence of MFD viscosity, the destabilizing effect of magnetization is depicted, but in its presence the magnetization may have a destabilizing or stabilizing effect. The critical wave number and critical magnetic thermal Rayleigh number for the onset of instability is determined numerically for sufficiently large values of the magnetic parameter M 1 . Graphs are plotted to depict the stability characteristics. The principle of exchange of stabilities is valid for a ferromagnetic fluid heated from below and saturating a porous medium

    Deciphering the biochemical pathway and pharmacokinetic study of amyloid βeta-42 with superparamagnetic iron oxide nanoparticles (SPIONs) using systems biology approach

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    Alzheimer’s disease (AD) pathogenesis leads to the appearance of senile plaques due to the production and deposition of the β-amyloid peptide (Aβ). Superparamagnetic iron oxide nanoparticles (SPIONs) have potential role in the detection and imaging of Aβ plaques in AD. SPIONs have shown appropriate potential in the diagnosis and treatment of AD. In the present study, the pharmacokinetics of SPIONs and its effect in the biochemical pathway of AD were analyzed using collected information. During analysis, the interaction of SPIONs with amyloid beta-42 (Aβ42), a biomarker for AD progression, has been shown. Nodes represent the entities and edges represent the relation (interactions) of one node to another node. Aβ42 and their interaction with other entities making up biochemical network are involved in AD mechanism in presence of SPION. The kinetic simulation was done to investigate pharmacokinetics of SPIONs for AD, where concentration was assigned of nanoparticles and other entities were applied as a kinetic irreversible simple Michaelis–Menten or mass action kinetics. Simulation was done in presence and absence of SPIONs to investigate pharmacokinetic effect in AD and explore the mechanism of Aβ42 in presence of SPIONs. This study may lead to better understanding, which is required to target the metabolism of Aß42 peptide, a pivotal player in this pathology
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