Metallurgical characterization of the fracture of several high strength aluminum alloys

The fracture behavior for structural aluminum alloys (2024, 6061, 7075, and 7178) was examined in selected heat treatments. The investigation included tensile, shear, and precracked notch-bend specimens fractured at ambient temperature under monotonic loading. Specimens were obtained from thin sheets and thick plates and were tested in longitudinal and transverse orientations at different strain rates. Microstructures of alloys were examined using the optical microscope and the scanning electron microscope with associated energy dispersive X ray chemical analysis. Several different types of second phase particles, some not reported by other investigators, were identified in the alloys. Fracture morphology was related to microstructural variables, test variables, and type of commercial product. Specimen orientation examined in the present investigation had little effect on fracture morphology. Test strain rate changes resulted in some change in shear fracture morphology, but not in fracture morphology of tensile specimens

A radiographic study of mandibular nutrient canals in patients with periodontal diseases

Nutrient canals are intra-osseous spaces or channels containing nerves and blood vessels. They are observed more frequently in the mandibular anterior region as radiolucent horizontal lines of varying widths, usually situated interproximally and inferiorly to the teeth. The aims of this investigation were to evaluate radiographically the presence of nutrient canals in 500 patients with periodontitis and 500 controls, to correlate their presence with severity of bone loss and trabecular bone pattern and to correlate the type of trabecular bone pattern to the age of the patient, bone loss and number of nutrient canals

Mindfulness and Acceptance during Transitions in Emerging Adults (The MATE Study)

Master's thesisEmerging adulthood is a developmental stage which involves personal, social, familial, cultural, biological, and psychological aspects of life. Significant decisions about career, life-partners, finances, education are made during this time. Studies suggest going through these transitions can lead to significant psychological distress. Studies also show that perceived social support can buffer the impact of these transitions on mental health outcomes. The current study assesses the moderating effects of psychological inflexibility and cognitive reactivity, constructs from ACT and MBCT, on the relationships between psychological distress, problematic drinking behavior, and perceived social support in emerging adults. Data were collected from 106 first-year college students from a small Midwest university. Participants completed self-report measures of distress, social support, cognitive reactivity, and psychological inflexibility. Psychological inflexibility and cognitive reactivity were positively associated with psychological distress and problematic drinking behavior, whereas psychological inflexibility and cognitive reactivity were negatively associated with perceived social support. Analyses of the potential moderating effects of psychological inflexibility and cognitive reactivity were not significant. The results suggest that developing mindfulness-based psychotherapy techniques uniquely directed towards the emerging adult population can be advantageous.https://deepblue.lib.umich.edu/bitstream/2027.42/145608/1/Bhandarkar - Mindfulness and Acceptance during Transitions in Emerging Adults (The MATE Study).pdf13Description of Bhandarkar - Mindfulness and Acceptance during Transitions in Emerging Adults (The MATE Study).pdf : Master's Thesi

IN00035 Indor Charter of the Time of Skandagupta

Bhandarkar, Devadatta Ramakrishna, Bahadur Chand Chhabra, and Govind Swamirao Gai, Inscriptions of the Early Gupta Kings (New Delhi: Archaeological Survey of India, 1981): 311-312

The chemistry of certain Amaryllidaceae alkaloids

The chemistry of alkaloids of the galanthamine group is reviewed. Oxidation of galanthamine with chromic acid or manganese dioxide to give narwedine and a minor product is described. On the basis of chemical and spectral data this minor product is shown to be keto-aldehyde containing a newly formed pyrrolidine ring. The structure of the phenolic alleloid chlidanthine of the galanthamine group has been determined by NO-dimethylation to give (-)-galanthamine methyl ether methiodide which was in turn prepared from (-)-galanthaminne via (-)-epigalanthamine. The relative stereochemistry of the pair of epimeric allylic alcohols derived from Pummerer's ketone has been determined. The conversion of these alcohols into allylic chlorides with thionyl chloride and with trisdimethylaminophosphine and carbon tetrachloride has been studied in detail. The biosynthesis of chlidanthine has been studied. Tritium-labelled (±)-narwedine, (±)-galanthamine and (±)-epigalanthamine were fed to Chlidanthus fragrans plants. Biosynthetic conversion of tritiated galanthamine and narwedine into chlidanthine was observed. Additionally. narwedine was efficiently converted into galanthamine thus confirming the long-suspected precursor–product relationship of these alkaloids. The observed lack of incorporation of (±)-epigalanthamine into chlidanthine served to confirm the relative configuration of the latter alkaloid

Computational Analysis of Dengue and Chikungunya Viral Gene Sequences To Elucidate Their Transmission and/or Symptoms Similarity

Dengue (DENV) and Chikungunya (CHIKV) viruses are enveloped positive-strand RNA mosquito-borne viruses that have been disseminated worldwide. Both the viruses are dissimilar in many aspects like genome organization and expression, particle size and taxonomical status except two similar aspects i.e. mode of transmission and the disease pathogenecity. Reports are indicating the co-infection of the both the viruses in a same patient. In view of similarities and/or dissimilarities between these two viruses, we indented to identify the existence of homology between any two gene sequences of which one from each virus. For this study we have analyzed all the structural and non structural nucleotide sequences of DENV type 1 (ACCESSION no. NC_001477) and CHIKV IND-06-Guj strain (ACCESSION no. JF272477) using the computational techniques. The results indicated that there is no homology between structural genes of both viruses. But analysis of the non-structural genes revealed that DENV NS4B and CHIKV nsp2 is showing the considerable homology. It is reported that DENV NS4B is involved in maintaining the replication balance in mosquito and human hosts. Hence we predict based on our results, CHIKV nsp2 which is showing homology with the DENV NS4B also serving same purpose in case of CHIKV. Further functional analysis of DENV NS4B and CHIKV nsP2 revealed the information that both have role in IFN inhibition and likely to have an important role in viral pathogenesis. Identification of common or shared epitopes on these polypeptides could lead to the development of an immunogen which could serve as vaccine candidate for both the viruses

IN00041 Sarnath Buddha Image Inscription 1 of the Time of Budhagupta

Bhandarkar, Devadatta Ramakrishna, Bahadur Chand Chhabra, and Govind Swamirao Gai, Inscriptions of the Early Gupta Kings (New Delhi: Archaeological Survey of India, 1981): 334

Repair of distal hypospadias: cosmetic or reconstructive

Objective: Hypospadias is one of the most common congenital anomalies of male genitalia and is usually repaired in the first 2 years of life. Regarding distal forms of hypospadias, however, controversies surrounding the need for surgical repair may lead to delayed referral secondary to symptoms. This article reviews the authors’ experience in boys who presented with symptoms secondary to an untreated distal hypospadias. / Materials and methods: The authors reviewed their prospectively maintained database and included all children who were secondarily referred because of symptoms due to untreated distal hypospadias in the last 5 years. The data were reviewed and analysed. / Results: Seventeen patients were identified. The median age at referral was 118 months. Symptoms at presentation included poor stream, straining during voiding, incontinence, and unhappiness related to cosmesis. Surgical correction included meatoplasty or tubularised incised plate urethroplasty. The choice between foreskin reconstruction or circumcision was based on parental preference. / Conclusion: The authors have presented a cohort of children with untreated distal hypospadias associated with functional and cosmetic problems. Both could be underestimated at birth, leading to problems in late childhood. Viewing repair of distal hypospadias as a purely cosmetic surgery is to disregard the nature of the anomaly and its associated implications