Report on consumer receipts data and sample-derived data in exposome research. Public deliverable 2.2

The scope of this paper is on exposome research in the context of the right to health and how the results of exposome research can contribute to a just society while, at the same time, the methods by which exposome research is performed adhere to applicable legal and ethical standards. Section 2 outlines exposome research as an approach to health research that aims to move away from approaches which focus on isolating and assessing singular exposures or risk factors, instead taking an integrated approach to the assessment and impact of exposures in their totality and full complexity. Section 3 defines health and dissects this definition in the right to health care and the right to health protection, the latter being public health. Section 3 further goes on to distinguish public health from the more individually focused 'medicine'. Exposome research is ultimately focused on public health. Section 4 outlines the context in which exposome research is placed within the confines of this paper, namely how the objectives of exposome research can contribute to a just society. Section 4.3 gives an overview of the themes and issues that play a role in the ethically and legally compliant methods of exposome research. Section 5 then gives concrete recommendations on the methods of exposome research and how these should foster trust and enhance participant engagement. Section 6 focuses on a consumer cohort as a concrete example of exposome research and looks at how the ethical and legal challenges were dealt with in this particular use case. The authors also give recommendations on how participant engagement as it is described in the paper could in the future be enhanced in this consumer cohort