Magnetic resonance imaging findings in dogs with thoracolumbar intervertebral disk disease: 69 cases (1997-2005)

Besalti, Omer/0000-0002-7819-9094;WOS: 000235977300025PubMed: 16536704Objective-To determine magnetic resonance imaging (MRI) abnormalities in dogs with intervertebral disk disease (IVDD) and develop a classification scheme for IVDD in dogs based on MRI findings. Design-Retrospective case series. Animals-69 dogs. Procedure-Medical records of dogs admitted because of thoracolumbar IVDD in which MRI of T9 through L7 had been performed were reviewed. Results-A total of 759 intervertebral disk spaces were examined. Of these, 342 (45.1%) were classified as having a normal MRI appearance; the remaining 417 (54.9%) had various types of IVDD. Disk degeneration was identified in 276 disk spaces in 56 dogs, bulging of the intervertebral disk was identified in 37 disk spaces in 24 dogs, disk protrusion was identified in 54 disk spaces in 32 dogs, and disk extrusion was identified in 50 disk spaces in 48 dogs. Cartilage endplate changes were identified in 35 vertebrae in 17 dogs, and increased signal intensity of the spinal cord was identified in 21 dogs. Conclusions and Clinical Relevance-Four types of IVDD (disk degeneration, bulging of the intervertebral disk, disk protrusion, and disk extrusion) were identified on the basis of MRI findings in dogs with thoracolumbar IVDD. We recommend that a standardized nomenclature be adopted for the various types of thoracolumbar IVDD in dogs

The Effect of Chronic Otitis Externa-Media on Brainstem Auditory Evoked Potentials in Dogs

WOS: 000263226200018The objective of the study was to present normative Brainstem Auditory Evoked Potentials (BAEP) data elicited by both air-conducted clicks (30 100 dBHL) and bone conducted clicks (100 1.30 dBHL) for healthy dogs, and dogs with chronic otitis externa-media (COEM). The data were analyzed to acquire reference values in 55 normal dogs and to estimate the degree of hearing, impairment associated with the disease. Filly-four dogs with COLM were divided into two degrees of security. The first one included dogs with severe (n 16), and the second with moderate COFM (n 38). The recognisability wave V was found higher than the others at every stimulation level. Wave VII was not seen by the bone-conducted click at all stimulation levels. and also in cases with severe COLM by the air.-conducted click. Recognisability of wave V was seen more than 50%, at 60 dBHL in severe COEM. This ratio was seen at 30 dBHL in moderate COLM. In healthy dogs, the latencies of waves (I VII) were compared between the left and the right side, and there were no significant differences between each side except tiff I shorter latency of wave VI. In conclusion, COEM caused increasing latency rather than total deafness, and BAFP can be suggested as an ancillary diagnostic tool in car disorders.TUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [VHAG 2003]This study was supported by TUBITAK as VHAG 2003

The evaluation of renal allo and autotransplantation results in cats

WOS: 000180152200023For the first time in Turkey, renal autotransplantation in 7 cats and renal allotransplantation in 7 cats having blood-crossmatch-compatible donors were performed. Immunosuppression was maintained by a prednisolone-cyclosporin combination in the renal allotransplantation group. All cats in the renal allotransplantation group died during the operation or between 3 and 72 h postoperatively. Two cats in the renal autotransplantation group survived approximately 2 years. Hyperacute or acute rejection findings were not encountered according to perioperative observations, laboratory findings or histopathological evaluations of renal allografts. The results of histopathological evaluations of renal allografts indicated acute tubular necrosis (ATN) findings caused by renal hypoperfusion due to hypotension. The reason for ATN was considered to be a result of hypotension that invasive methods could not control

Serum biochemistry and native protein electrophoresis in diarrheic calves with arthritis

In this study, serum biochemistry and native protein electrophoresis in newborn calves with diarrhea and arthritis, were performed in order to evaluate the changes along with clinical findings for their possible application in the diagnosis and prognosis of disease. Based on clinical examination, animals were allotied into two groups comprising either diseased or healthy animals. Urea, creatinine, ALT, AST, LDH, albumin, total protein, glucose, total cholesterol, uric acid and iron levels were determined in the sera. Serum protein native polyacrilamide gel electrophoresis (nPAGE) was performed followed by protein band ratio estimation supported with densitometry at 596 nm. Differences between the average mean of healthy and diseased animals were compared statistically (Kruskal-Walley test). In this study a decrease in serum glucose and cholesterol values (p<0.001), increase in urea, LDH levels and α1-and α2-globulin levels (p<0.01 and p<0.05 respectively) were found to be associated with the disease. As a result, the observed significant changes in biochemical parameters and clinical investigation in calves, suggesting acute inflammation causing the decrease in glucose and increase in α-globulins, may be of prognostic value