88 research outputs found

    Preference Formation, School Dissatisfaction and Risky Behavior of Adolescents

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    School dissatisfaction is an important component of the subjective well-being of adolescents associated with "risky behavior" like drug use, unprotected sex, norm violations and illegal behavior. We extend the standard human capital model to joint human investment (education) and disinvestment (risky behavior). Based on this model, we develop a general dynamic framework to analyze the preference formation of children and behavioral change at school. Once an educational norm is set by adults, children can rationally deviate from this norm, while staying at school, after experiencing bad surprises like a school failure. The same type of dynamic equation can be used in a sequence to predict education, satisfaction with school, and a host of risky behavior. We test these assumptions with a unique panel data set on American adolescents attending middle or high school. School dissatisfaction is found to have a significant positive effect upon nine different types of risky behavior.Education; Satisfaction; Risky behavior; Preference formation; Economic behavior of children

    Dynamical modeling of bi-layer Aluminium adhesive tape for laser shock applications

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    The presented work covers the response of Aluminium tape (Al tape) under high strain rate of deformation (order of 106s−1) using laser shock. High power laser (J) with a short pulse duration (ns) is used to create laser shock within the water confinement regime on two Al tape configurations in order to apply low and high pressure (order of MPa and GPa). Al tape has been modeled using Johnson-Cook (J-C) material model for the Al layer, and Steinberg–Cochran–Guinan (SCG) material model (elastic with pressure dependence) for the adhesive layer, both material models are coupled with Grüneisen equation of state. The Al tape model has been validated by comparing the simulated Back Face Velocity (BFV) of the target with the measured one by the Velocity Interferometer System for Any Reflector (VISAR). In addition, the validated material model is used to conduct the sensitivity studies about the transmitted pressure depending on the acoustical impedance of the target and adhesive thickness. Moreover, location and magnitude of maximum tensile stress within the target are calculated in function of the adhesive thickness of the Al tape. Finally, it has been proved that using one laser beam configuration, maximum tensile zone could appears close to the front face by increasing the adhesive thickness

    Laser shock peening: toward the tse of pliable polid polymers for confinement

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    This paper presents the first extensive study of the performances of solid polymers used as confinement materials for laser shock applications such as laser shock peening (LSP) as opposed to the exclusively used water-confined regime up to now. The use of this new confinement approach allows the treatment of metal pieces needing fatigue behavior enhancement but located in areas which are sensitive to water. Accurate pressure determination in the polymer confinement regime was performed by coupling finite element simulation and experimental measurements of rear free-surface velocity using the velocity interferometer system for any reflector (VISAR). Pressure could reach 7.6 and 4.6 GPa for acrylate-based polymer and cross-linked polydimethylsiloxane (PDMS), respectively. At 7 and 4.7 GW/cm2, respectively, detrimental laser breakdown limited pressure for acrylate and PDMS. These results show that the pressures produced were also as high as in water confinement, attaining values allowing the treatment of all types of metals with LSP and laying the groundwork for future determination of the fatigue behavior exhibited by this type of treated materials

    Search for the standard model Higgs boson at LEP

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    DMTs and Covid-19 severity in MS: a pooled analysis from Italy and France

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    We evaluated the effect of DMTs on Covid-19 severity in patients with MS, with a pooled-analysis of two large cohorts from Italy and France. The association of baseline characteristics and DMTs with Covid-19 severity was assessed by multivariate ordinal-logistic models and pooled by a fixed-effect meta-analysis. 1066 patients with MS from Italy and 721 from France were included. In the multivariate model, anti-CD20 therapies were significantly associated (OR = 2.05, 95%CI = 1.39–3.02, p < 0.001) with Covid-19 severity, whereas interferon indicated a decreased risk (OR = 0.42, 95%CI = 0.18–0.99, p = 0.047). This pooled-analysis confirms an increased risk of severe Covid-19 in patients on anti-CD20 therapies and supports the protective role of interferon

    Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome associated with COVID-19: An Emulated Target Trial Analysis.

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    RATIONALE: Whether COVID patients may benefit from extracorporeal membrane oxygenation (ECMO) compared with conventional invasive mechanical ventilation (IMV) remains unknown. OBJECTIVES: To estimate the effect of ECMO on 90-Day mortality vs IMV only Methods: Among 4,244 critically ill adult patients with COVID-19 included in a multicenter cohort study, we emulated a target trial comparing the treatment strategies of initiating ECMO vs. no ECMO within 7 days of IMV in patients with severe acute respiratory distress syndrome (PaO2/FiO2 <80 or PaCO2 ≥60 mmHg). We controlled for confounding using a multivariable Cox model based on predefined variables. MAIN RESULTS: 1,235 patients met the full eligibility criteria for the emulated trial, among whom 164 patients initiated ECMO. The ECMO strategy had a higher survival probability at Day-7 from the onset of eligibility criteria (87% vs 83%, risk difference: 4%, 95% CI 0;9%) which decreased during follow-up (survival at Day-90: 63% vs 65%, risk difference: -2%, 95% CI -10;5%). However, ECMO was associated with higher survival when performed in high-volume ECMO centers or in regions where a specific ECMO network organization was set up to handle high demand, and when initiated within the first 4 days of MV and in profoundly hypoxemic patients. CONCLUSIONS: In an emulated trial based on a nationwide COVID-19 cohort, we found differential survival over time of an ECMO compared with a no-ECMO strategy. However, ECMO was consistently associated with better outcomes when performed in high-volume centers and in regions with ECMO capacities specifically organized to handle high demand. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/)

    ETUDE OSTEOMORPHOMETRIQUE DU COXAL ET DU SACRUM CHEZ DES RACES DE CHIENS PREDISPOSES A LA DYSPLASIE DE LA HANCHE, APPLICATION A LA CREATION D'UNE NOUVELLE PLAQUE DE TRIPLE OSTEOTOMIE DU BASSIN

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    La triple ostéotomie du bassin est une opération complexe qui gagnerait à être standardisée. Ses principales complications sont le lâchage d'implants et le rétrécissement de la filière pelvienne. L'objectif de notre étude était de créer une nouvelle plaque de triple ostéotomie adaptable à tout chien de race prédisposée à la dysplasie, en s'assurant d'ancrer deux vis dans le sacrum pour limiter le lâchage d'implants. Cette étude porta sur trois races de chiens prédisposées à la dysplasie, le labrador, le berger allemand et le rottweiler. La population étudiée était constituée de douze chiens , à raison de quatre spécimens par race. L'étude ostéomorphométrique du coxal et du sacrum a révélé une variabilité importante, directement dépendante de la race, la surface du corps sacral présente une variation allant de 181 mm' à 304 mm' dans l'échantillon étudié. De plus, à cette variation importante s'ajoute l'absence de portion commune de corps sacral à l'ensemble de l'échantillon. L'absence de bassin standard et de projection commune de corps sacral compromet la réalisation d'une plaque standard de triple ostéotomie du bassin.MAISONS-ALFORT-Ecole Vétérin (940462302) / SudocSudocFranceF

    Preference Formation, School Dissatisfaction <br />and Risky Behavior of Adolescents

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    International audienceSchool dissatisfaction is an important component of the subjective well-being of adolescents associated with "risky behavior" like drug use, unprotected sex, norm violations and illegal behavior. We extend the standard human capital model to joint human investment (education) and disinvestment (risky behavior). Based on this model, we develop a general dynamic framework to analyze the preference formation of children and behavioral change at school. Once an educational norm is set by adults, children can rationally deviate from this norm, while staying at school, after experiencing bad surprises like a school failure. The same type of dynamic equation can be used in a sequence to predict education, satisfaction with school, and a host of risky behavior. We test these assumptions with a unique panel data set on American adolescents attending middle or high school. School dissatisfaction is found to have a significant positive effect upon nine different types of risky behavior
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