Case report 223. Benign fibrous histiocytoma.

Case report 223. Benign fibrous histiocytoma

Primary central (medullary) fibrosarcoma of bone

Eighty cases of primary fibrosarcoma of bone from the Rizzoli Institute are reviewed. There was a slight male predominance with a wide patient age distribution. Roentgenologically, low grade fibrosarcomas had generally well-defined margins and a 'soap-bubble' appearance. High grade tumors appeared permeative and more aggressive. Histologically, the majority of tumors were high grade (3 and 4). Prognosis correlated well with the grade of the tumor. The 10-year survival rate was 83% for low grade sarcomas and 34% for high grade tumors. Local recurrence was a bad prognostic sign

Preoperative chemotherapy by intra-arterial infusion for osteosarcoma of the extremities. Local results of a pilot study including 50 patients

Preoperative chemotherapy by intra-arterial infusion for osteosarcoma of the extremities. Local results of a pilot study including 50 patients