37 research outputs found
Public-common partnerships, autogestion, and the right to the city
The chapter will proceed through providing a critical engagement with Lefebvre's theorization of autogestion and the Right to the City, suggesting that it offers an entry point for conceptualizing a politics of self-government that is both in, against and beyond the state. The chapter outlines our proposed new model of ownership and governance which seeks to embody such a directional strategy, the Public-Common Partnership (PCP). We argue that PCPs offer a strategic approach that sets in motion processes that work to shift the boundaries of social and political possibility, developing a politics of the common that takes the question of the state seriously
Carry on camping? The British Camp for Climate Action as a political refrain
The chapter engages with the notion of âpolitical refrain', adapted from the work of Gilles Deleuze and Felix Guattari, to offer some reflections on the strengths and limitations of protest camps in the action repertoire available to social movements. In the present study, âcamping' was a recurring thematic for British environmental protest, especially in the mobilisations of the Camp for Climate Action. Camps played more than a simple organisational role and signified a desire to prefigure alternative social and ecological configurations. The camp-form, however, took on a logic of its own, locking the protest movement into repertoire dependency, which signified the problematic tension between organisational continuity and tactical innovation. Unable to resolve this tension, and with British climate activism so fundamentally tied to the imaginary of the protest camp, the emergence of a new political praxis was prevented
Politicising proximity: radical municipalism as a strategy in crisis
Altres ajuts: Economic and Social Research Council (ES/S012435/1: WISERD Civil Society: Changing perspectives on Civic Stratification and Civil Repair) ; Leverhulme Trust (ECF-2018-477: Reimagining the City: New Municipalism and the future of economic democracy)As new municipalism comes of age, prefixes proliferate: from democratic and autonomist to post-growth and care municipalisms. How do all these variegations relate to each other and to the wider movement of which they claim a part? What does all this conceptual creativity amount to, epistemologically and politically? How can we distill the most salient lessons for the further development of theory and practice in the years ahead? This article is our attempt to answer such questions and to define more precisely the contours of this emerging field of praxis. First, we delineate within new municipalism the target of our analytical gaze -radical municipalism. Radical municipalism is not simply progressive policies happening in cities, and should not be conflated with pragmatic, entrepreneurial or state-centric perspectives. Rather, we argue it is a speculative hypothesis about how systemic transformation might be wrought through coordinated action at the urban or municipal scale, understood as a strategic entry-point for counter-hegemonic strug- gle. Key here is proximity and the politicisation and socialisation of proximate relations of encoun- ter and assembly. Second, we delve deeper into what we identify as four salient dimensions marking this terrain - economic reorganisation, democratisation of political decision-making, fem- inisation of politics, ecological transformation - as a multi-dimensional lens through which to introduce, and situate within the wider literature, the 15 articles that comprise this double special issue. Throughout these contributions to the theory and practice of municipalist strategy, the issue of crisis looms large: both historically, as an animating spur to action and opportunity for political intervention, and operationally, as a structuring condition and limiting factor of a strategy arguably in crisis itself. Finally, we reflect on the epistemological, methodological and political implications of pursuing radical municipalist strategies in the current conjuncture
Placing the Foundational Economy: An emerging discourse for post-neoliberal economic development
Emerging in the mid-2010s, the Foundational Economy has been heralded as âa compelling counter-project against neoliberalismâ and âan alternative pathway ⊠[for] progressive political renewalâ. Grounded in a review of cross-disciplinary debates, this paper introduces the concept of the Foundational Economy and places it in relation to heterodox geographic theories of socio-economic development such as the âsocial economyâ and âdiverse economiesâ literature. Whilst there are clear overlaps, the concept of the Foundational Economy can be distinguished through its commitment to (a) a zonal perspective; (b) a focus on maximalist social innovations; and (c) the reconstitution of citizenship. In radical combination, it is argued that the lens of the Foundational Economy facilitates âa trenchant critique and denaturalization of current conditions, in tandem with creative explorations of the political economy of alternativesâ. The paper concludes by reflecting on current oversights and future research trajectories for Foundational Economy research
Placing the Foundational Economy: An emerging discourse for post-neoliberal economic development
Emerging in the mid-2010s, the Foundational Economy has been heralded as âa compelling counter-project against neoliberalismâ and âan alternative pathway ⊠[for] progressive political renewalâ. Grounded in a review of cross-disciplinary debates, this paper introduces the concept of the Foundational Economy and places it in relation to heterodox geographic theories of socio-economic development such as the âsocial economyâ and âdiverse economiesâ literature. Whilst there are clear overlaps, the concept of the Foundational Economy can be distinguished through its commitment to (a) a zonal perspective; (b) a focus on maximalist social innovations; and (c) the reconstitution of citizenship. In radical combination, it is argued that the lens of the Foundational Economy facilitates âa trenchant critique and denaturalization of current conditions, in tandem with creative explorations of the political economy of alternativesâ. The paper concludes by reflecting on current oversights and future research trajectories for Foundational Economy research
Research Report: North Wales Growth Deal
This report was produced in November 2022 as part of research undertaken by the Wales Institute of Social and Economic Research and Data (WISERD) as part of its ESRC Centre research programme. Fifteen remote interviews were conducted in English or Welsh (depending on the participantâs choice) by three researchers (Dr Beel, Prof IR Jones, Dr Russell). A range of potential participants were identified in dialogue with Alwen Williams the Programme Director of the North Wales Growth Deal (NWGD), from which we sampled a cross-section of interviewees, supplemented by interviews with a small number of political leaders. Whilst the interviewees will remain anonymous, they included: lead officers for economy, regeneration and development, local authority chief executives, NWGD team members, chief executives/managing director of NWGD partners, and local authority leaders. The interviews were supplemented with a limited review of reports and minutes associated with the NWGD. The interview schedule had been co-developed with members of the NWGD team and were conducted with a semi-structured approach. The interviews were transcribed and analysed using qualitative data processing software (NVivo). Interview transcripts can be made available on request by interviewees. These interviews were conducted as part of a wider research project focused on the role of regional economic development policy in supporting the strengthening of the Foundational Economy. The research was given ethical approval by the Cardiff University School of Social Sciences Research Ethics Committee (Reference Number: SREC/4077
Impact of molecular genetic methods on the initiation of chemotherapy in multiple drug resistant tuberculosis patients in Arkhangelsk Region
In the Arkhangelsk Region, the prevalence of multiple drug-resistant tuberculosis is one of the highest in the world. In 2016, the portion of multiple drug resistant tuberculosis made 33.1% among new cases and 59.5% among relapses. Using new molecular genetic diagnostic techniques allows reducing the time for diagnostics of tuberculosis and drug resistance and should result in the earlier start of adequate treatment.
The goal of the study is to assess the impact of new diagnostic molecular genetic methods on the time period from the first referral for medical care till the start of MDR-TB treatment. It was assumed that the introduction of molecular genetic tests would lead to early initiation of treatment in MDR TB patients (the research project of the International Union Against Tuberculosis and Lung Diseases and Tuberculosis Control Program of Arkhangelsk Region on The PROVE-IT LPA; Policy Relevant Outcomes from Validating Evidence on Impact of Line Probe Assays).
Subjects and Methods. The results of the diagnostic procedure using cultures were compared with the results of the procedure based on molecular genetic tests aimed to detect MDR-TB. 295 MDR TB patients were enrolled into the study, of them, 163 had culture and 132 had molecular genetic tests.
Results. The use of molecular genetic tests in smear-positive patients (AFB+) resulted in the reduction of the time period before initiation of MDRTB treatment by 50 and 66 days (median) versus culture by BacTAlert and absolute concentration on Lowenstein-Jensen medium respectively (p <0.001).
Patients with a negative smear (AFB-), in whom MDR TB was detected by molecular genetic methods started treatment by 78 days earlier (median) versus patients who had culture (Lowenstein-Jensen, p < 0.001). Despite the significant reduction in the time period, even using molecular genetic methods, it took 24 days for cases with AFB+ and 62 days for cases with AFB- to be notified and start treatment of MDR TB
The Use of Molecular Genetic Diagnostic Tests to Improve MDR TB Treatment Outcomes in Arkhangelsk Region
The use of molecular genetic tests as a part of tuberculosis patients examination made it possible to reduce the time for TB diagnosis and determination of drug resistance (DR) of M. tuberculosis (MTB) in Arkhangelsk Region. Early detection of multiple drug resistant tuberculosis (MDR TB) made it possible to prescribe the adequate chemotherapy regimen promptly and thus to improve treatment outcomes.
The objective of the study: to evaluate the results of treatment of MDR TB patients in whom MDR TB was diagnosed by molecular genetic tests. It was assumed that the introduction of molecular genetic tests would result in improved treatment outcomes in MDR TB patients [(the research project of the International Union Against Tuberculosis and Lung Diseases and Tuberculosis Control Program of Arkhangelsk Region of the PROVE-IT LPA (Policy Relevant Outcomes from Validating Evidence on Impact of Line Probe Assays)].
Subjects: 295 MDR TB patients detected in Arkhangelsk Region were enrolled in the study. MDR TB was detected by molecular genetic tests in the main group (132 patients) and by culture in the control group (163 patients). Patients from both groups received the standard chemotherapy regimen. Chemotherapy outcomes were compared in both groups.
Results. Treatment outcomes were better in the group (MGT group) where molecular genetic tests were used for drug susceptibility testing (p = 0.003) versus the comparison group where the culture was used. Effective treatment was documented more frequently (65.2%) in the MGT group versus the comparison group (44.8%). All-cause mortality was lower in the MGT group (7.6%) than in the comparison group (15.9%). There were no statistically significant differences between the groups in the time when sputum conversion (by smear and culture) was achieved.
Key words: tuberculosis, multiple drug resistant M. tuberculosis, molecular genetic diagnostic test
The mineral composition and spatial distribution of the dust ejecta of NGC 6302
We have analysed the full ISO spectrum of the planetary nebula NGC 6302 in
order to derive the mineralogical composition of the dust in the nebula. We use
an optically thin dust model in combination with laboratory measurements of
cosmic dust analogues. We find two main temperature components at about 100 and
50 K respectively, with distinctly different dust compositions. The warm
component contains an important contribution from dust without strong infrared
resonances. In particular the presence of small warm amorphous silicate grains
can be excluded. The detection of weak PAH bands also points to a peculiar
chemical composition of the dust in this oxygen-rich nebula. The cool dust
component contains the bulk of the mass and shows strong emission from
crystalline silicates, which contain about 10 percent of the mass. In addition,
we identify the 92 micron band with the mineral calcite, and argue that the 60
micron band contains a contribution from the carbonate dolomite. We present the
mass absorption coefficients of six different carbonate minerals. The geometry
of the dust shell around NGC 6302 is studied with mid-infrared images obtained
with TIMMI2. We argue that the cool dust component is present in a
circumstellar dust torus, while the diffuse emission from the warm component
originates from the lobes.Comment: 13 pages, 10 figures, accepted for publication in A&
The impact of a line probe assay based diagnostic algorithm on time to treatment initiation and treatment outcomes for multidrug resistant TB patients in Arkhangelsk region, Russia
BACKGROUND: In the Arkhangelsk region of Northern Russia, multidrug-resistant (MDR) tuberculosis (TB) rates in new cases are amongst the highest in the world. In 2014, MDR-TB rates reached 31.7% among new cases and 56.9% among retreatment cases. The development of new diagnostic tools allows for faster detection of both TB and MDR-TB and should lead to reduced transmission by earlier initiation of anti-TB therapy. STUDY AIM: The PROVE-IT (Policy Relevant Outcomes from Validating Evidence on Impact) Russia study aimed to assess the impact of the implementation of line probe assay (LPA) as part of an LPA-based diagnostic algorithm for patients with presumptive MDR-TB focusing on time to treatment initiation with time from first-care seeking visit to the initiation of MDR-TB treatment rather than diagnostic accuracy as the primary outcome, and to assess treatment outcomes. We hypothesized that the implementation of LPA would result in faster time to treatment initiation and better treatment outcomes. METHODS: A culture-based diagnostic algorithm used prior to LPA implementation was compared to an LPA-based algorithm that replaced BacTAlert and Löwenstein Jensen (LJ) for drug sensitivity testing. A total of 295 MDR-TB patients were included in the study, 163 diagnosed with the culture-based algorithm, 132 with the LPA-based algorithm. RESULTS: Among smear positive patients, the implementation of the LPA-based algorithm was associated with a median decrease in time to MDR-TB treatment initiation of 50 and 66 days compared to the culture-based algorithm (BacTAlert and LJ respectively, p<0.001). In smear negative patients, the LPA-based algorithm was associated with a median decrease in time to MDR-TB treatment initiation of 78 days when compared to the culture-based algorithm (LJ, p<0.001). However, several weeks were still needed for treatment initiation in LPA-based algorithm, 24 days in smear positive, and 62 days in smear negative patients. Overall treatment outcomes were better in LPA-based algorithm compared to culture-based algorithm (p = 0.003). Treatment success rates at 20 months of treatment were higher in patients diagnosed with the LPA-based algorithm (65.2%) as compared to those diagnosed with the culture-based algorithm (44.8%). Mortality was also lower in the LPA-based algorithm group (7.6%) compared to the culture-based algorithm group (15.9%). There was no statistically significant difference in smear and culture conversion rates between the two algorithms. CONCLUSION: The results of the study suggest that the introduction of LPA leads to faster time to MDR diagnosis and earlier treatment initiation as well as better treatment outcomes for patients with MDR-TB. These findings also highlight the need for further improvements within the health system to reduce both patient and diagnostic delays to truly optimize the impact of new, rapid diagnostics