Shielding Effectiveness Measurements using a Reverberation Chamber

Shielding effectiveness measurements have been performed using a reverberation chamber. The reverberation chamber methodology as we1l as the measurement setup is described and some results are given. Samples include glass reinforced plastic panels, aluminum panels with many holes, wire mesh, among others. The reverberation chamber setup gives very repeatable measurement results

Musical Women and Identity-Building in Early Independent Mexico (1821-1854)

This thesis investigates music in Mexico City, with an emphasis on women's relationship to Romanticism, education, consumption, domestic music-making and public performance. During the first decades after independence in 1821, Mexicans began the process of constructing an identity, which musically speaking meant an expansion of the secular musical world. Such construction involved the development of internal activity alongside a conditional receptivity to external influence in the form of the visits of Italian opera companies such as those of Manuel García and Max Maretzek, and travelling virtuosi such as pianist virtuoso Henri Herz, who brought new repertoire and performance practices to Mexican theatres and homes. As consumers and as musicians, women were at the centre of such developments. In Mexico, both European music and that of local musicians was disseminated by means of ladies’ journals and imported and locally-printed sheet music by foreign and Mexican composers, in order to supply a growing home market for amateurs. Abundant surviving repertoire for the home, the widespread availability of musical instruction as revealed through advertisements, and witness accounts of soirées and concerts in the theatre reveal a budding musical world that has hitherto been overlooked and which occurred during a period generally deemed of little importance in Mexican musical history. By investigating a key period in the social-cultural history of Mexican music, this thesis crafts a narrative of intersections between the musical life of Mexican women and the incipient construction of a musical-cultural identity

GAA Deficiency in Pompe Disease Is Alleviated by Exon Inclusion in iPSC-Derived Skeletal Muscle Cells

Pompe disease is a metabolic myopathy caused by deficiency of the acid α-glucosidase (GAA) enzyme and results in progressive wasting of skeletal muscle cells. The c.-32-13T>G (IVS1) GAA variant promotes exon 2 skipping during pre-mRNA splicing and is the most common variant for the childhood/adult disease form. We previously identified antisense oligonucleotides (AONs) that promoted GAA exon 2 inclusion in patient-derived fibroblasts. It was unknown how these AONs would affect GAA splicing in skeletal muscle cells. To test this, we expanded induced pluripotent stem cell (iPSC)-derived myogenic progenitors and differentiated these to multinucleated myotubes. AONs restored splicing in myotubes to a similar extent as in fibroblasts, suggesting that they act by modulating the action of shared splicing regulators. AONs targeted the putative polypyrimidine tract of a cryptic splice acceptor site that was part of a pseudo exon in GAA intron 1. Blocking of the cryptic splice donor of the pseudo exon with AONs likewise promoted GAA exon 2 inclusion. The simultaneous blocking of the cryptic acceptor and cryptic donor sites restored the majority of canonical splicing and alleviated GAA enzyme deficiency. These results highlight the relevance of cryptic splicing in human disease and its potential as therapeutic target for splicing modulation using AONs

Behavioral model for common mode filter and performance optimization aspects

A well designed common mode filter for motor drive application can significantly improve the level of electromagnetic interference generated by the cable and the motor housing. The subsequent design of this filter is strongly dependent on the actual in situ parameters of the motor drive and often leads to a "cut and try" process. To simplify this process a novel behavioral model for common mode choke (CMC) is proposed. The model can be used to show the influence of the designable parameters on the final performance of the choke placed in a circuit. The identification of the model uncertainties can be used to evaluate the upper and lower limits of the final attenuation

TEMPEST Zoning for Complex Platforms

The electromagnetic topology and electromagnetic zoning challenges for TEMPEST are compared to zoning as used in other pillars within the electromagnetic compatibility domain, like nuclear electromagnetic pulse, lightning and lightning electromagnetic pulses, and electromagnetic interference. The objectives are the same, but the development of procedures, requirements and methodology have been developed in separate pillars resulting in different approaches. However, this paper shows that the zoning is actually the same, and gives some recommendation for requirements and verification methods

Shielding Effectiveness of Cabinets using IEEE 299 and IEEE 299.1 and Effect of Loading

One major electromagnetic compatibility technique is shielding. It is the basic technique to create a barrier between different electromagnetic zones. Shielding effectiveness measurement procedures are compared, and applied to a cabinet. Flaws in measurement procedures and some suggestions for improvements are discussed. Loading a cabinet with equipment and the effect on shielding effectiveness is shown

Using an in-line uninterruptable power supply as TEMPEST 'filter' for naval vessels

A major objective of TEMPEST engineering is to separate equipment carrying classified (=RED) data from equipment carrying unclassified (=BLACK) data, to prevent unintentional radio or electrical signals, containing classified data, emission. RED/BLACK separation in the power supply system is in general achieved by adding TEMPEST filters, but on board naval vessels the power system is insulated and the use of filter capacitances is limited. Solid-state uninterruptable power supplies (UPS) create isolation, because of the AC/DC and DC/AC conversion and associated internal filtering. Measurements have been performed on an operational UPS to determine the a-symmetrical, symmetrical and non-symmetrical isolation. The results obtained from the UPS tested show very good isolation which, combined with the already installed power line filters inside equipment, will be more than adequate to achieve the required isolation for RED/BLACK separatio