1,204 research outputs found

    Weak solutions to problems involving inviscid fluids

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    We consider an abstract functional-differential equation derived from the pressure-less Euler system with variable coefficients that includes several systems of partial differential equations arising in the fluid mechanics. Using the method of convex integration we show the existence of infinitely many weak solutions for prescribed initial data and kinetic energy

    Phage displayed peptides/antibodies recognizing growth factors and their tyrosine kinase receptors as tools for anti-cancer therapeutics.

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    The basic idea of displaying peptides on a phage, introduced by George P. Smith in 1985, was greatly developed and improved by McCafferty and colleagues at the MRC Laboratory of Molecular Biology and, later, by Barbas and colleagues at the Scripps Research Institute. Their approach was dedicated to building a system for the production of antibodies, similar to a naĂŻve B cell repertoire, in order to by-pass the standard hybridoma technology that requires animal immunization. Both groups merged the phage display technology with an antibody library to obtain a huge number of phage variants, each of them carrying a specific antibody ready to bind its target molecule, allowing, later on, rare phage (one in a million) to be isolated by affinity chromatography. Here, we will briefly review the basis of the technology and the therapeutic application of phage-derived bioactive molecules when addressed against key players in tumor development and progression: growth factors and their tyrosine kinase receptors

    Monogenoidean parasites of fishes associated with coral reefs in the Ras Mohammed National Park, Egypt: preliminary results

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    AbstractA parasitological survey of the monogenoids of 14 species of common fishes associated with the local coral reefs of the Ras Mohammed National Park, National Parks of Egypt South Sinai Sector, Egypt, was carried out from May 2003 to May 2005. The monogenoids collected during the survey included 17 species: 8 previously described species, 7 new species in established genera, and 2 new species belonging to new genera

    The scaling behaviour of screened polyelectrolytes

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    We present a field-theoretic renormalization group (RG) analysis of a single flexible, screened polyelectrolyte chain (a Debye-H\"uckel chain) in a polar solvent. We point out that the Debye-H\"uckel chain may be mapped onto a local field theory which has the same fixed point as a generalised n→1n \to 1 Potts model. Systematic analysis of the field theory shows that the system is one with two interplaying length-scales requiring the calculation of scaling functions as well as exponents to fully describe its physical behaviour. To illustrate this, we solve the RG equation and explicitly calculate the exponents and the mean end-to-end length of the chain.Comment: 6 pages, 1 figure; changed title and slight modification to tex

    Crossover from Isotropic to Directed Percolation

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    Percolation clusters are probably the simplest example for scale--invariant structures which either are governed by isotropic scaling--laws (``self--similarity'') or --- as in the case of directed percolation --- may display anisotropic scaling behavior (``self--affinity''). Taking advantage of the fact that both isotropic and directed bond percolation (with one preferred direction) may be mapped onto corresponding variants of (Reggeon) field theory, we discuss the crossover between self--similar and self--affine scaling. This has been a long--standing and yet unsolved problem because it is accompanied by different upper critical dimensions: dcI=6d_c^{\rm I} = 6 for isotropic, and dcD=5d_c^{\rm D} = 5 for directed percolation, respectively. Using a generalized subtraction scheme we show that this crossover may nevertheless be treated consistently within the framework of renormalization group theory. We identify the corresponding crossover exponent, and calculate effective exponents for different length scales and the pair correlation function to one--loop order. Thus we are able to predict at which characteristic anisotropy scale the crossover should occur. The results are subject to direct tests by both computer simulations and experiment. We emphasize the broad range of applicability of the proposed method.Comment: 19 pages, written in RevTeX, 12 figures available upon request (from [email protected] or [email protected]), EF/UCT--94/2, to be published in Phys. Rev. E (May 1994

    Strong Deformation Effects in Hot Rotating 46Ti

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    Exotic-deformation effects in 46Ti nucleus were investigated by analysing the high-energy gamma-ray and the alpha-particle energy spectra. One of the experiments was performed using the charged-particle multi-detector array ICARE together with a large volume (4"x4") BGO detector. The study focused on simultaneous measurement of light charged particles and gamma-rays in coincidence with the evaporation residues. The experimental data show a signature of very large deformations of the compound nucleus in the Jacobi transition region at the highest spins. These results are compared to data from previous experiments performed with the HECTOR array coupled to the EUROBALL array, where it was found that the GDR strength function is highly fragmented, strongly indicating a presence of nuclei with very large deformation.Comment: 10 pages, 6 figures, Proceedings of the Zakopane Conference on Nuclear Physics, to be published in Acta Phys. Pol. B (2007

    GDR Feeding of the Highly-Deformed Band in 42Ca

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    The gamma-ray spectra from the decay of the GDR in the compound nucleus reaction 18O+28Si at bombarding energy of 105 MeV have been measured in an experiment using the EUROBALL IV and HECTOR arrays. The obtained experimental GDR strength function is highly fragmented, with a low energy (10 MeV) component, indicating a presence of a large deformation and Coriolis effects. In addition, the preferential feeding of the highly-deformed band in 42Ca by this GDR low energy component is observed.Comment: 6 pages, 2 figures, Proceedings of the Zakopane2004 Symposium, to be published in Acta Phys. Pol. B36 (2005

    Two-way multi-lane traffic model for pedestrians in corridors

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    We extend the Aw-Rascle macroscopic model of car traffic into a two-way multi-lane model of pedestrian traffic. Within this model, we propose a technique for the handling of the congestion constraint, i.e. the fact that the pedestrian density cannot exceed a maximal density corresponding to contact between pedestrians. In a first step, we propose a singularly perturbed pressure relation which models the fact that the pedestrian velocity is considerably reduced, if not blocked, at congestion. In a second step, we carry over the singular limit into the model and show that abrupt transitions between compressible flow (in the uncongested regions) to incompressible flow (in congested regions) occur. We also investigate the hyperbolicity of the two-way models and show that they can lose their hyperbolicity in some cases. We study a diffusive correction of these models and discuss the characteristic time and length scales of the instability

    Random Resistor-Diode Networks and the Crossover from Isotropic to Directed Percolation

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    By employing the methods of renormalized field theory we show that the percolation behavior of random resistor-diode networks near the multicritical line belongs to the universality class of isotropic percolation. We construct a mesoscopic model from the general epidemic process by including a relevant isotropy-breaking perturbation. We present a two-loop calculation of the crossover exponent ϕ\phi. Upon blending the ϵ\epsilon-expansion result with the exact value ϕ=1\phi =1 for one dimension by a rational approximation, we obtain for two dimensions ϕ=1.29±0.05\phi = 1.29\pm 0.05. This value is in agreement with the recent simulations of a two-dimensional random diode network by Inui, Kakuno, Tretyakov, Komatsu, and Kameoka, who found an order parameter exponent β\beta different from those of isotropic and directed percolation. Furthermore, we reconsider the theory of the full crossover from isotropic to directed percolation by Frey, T\"{a}uber, and Schwabl and clear up some minor shortcomings.Comment: 24 pages, 2 figure
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