From prescriptive programming of solid-state devices to orchestrated self-organisation of informed matter

Achieving real-time response to complex, ambiguous, high-bandwidth data is impractical with conventional programming. Only the narrow class of compressible input-output maps can be specified with feasibly sized programs. Present computing concepts enforce formalisms that are arbitrary from the perspective of the physics underlying their implementation. Efficient physical realizations are embarrassed by the need to implement the rigidly specified instructions requisite for programmable systems. The conventional paradigm of erecting strong constraints and potential barriers that narrowly prescribe structure and precisely control system state needs to be complemented with a new approach that relinquishes detailed control and reckons with autonomous building blocks. Brittle prescriptive control will need to be replaced with resilient self-organisation to approach the robustness and efficiency afforded by natural systems. Structure-function self-consistency will be key to the spontaneous generation of functional architectures that can harness novel molecular and nano materials in an effective way for increased computational power

A Framework for Modeling DNA Based Molecular Systems

Abstract. In this paper, we propose a framework for a discrete event simulator for simulating the DNA based nano-robotical systems. We describe a physical model that captures the conformational changes of the solute molecules. We also present methods to simulate various chemical reactions due to the molecular collisions, including hybridization, dehybridization and strand displacement. The feasibility of such a framework is demonstrated by some preliminary results. 1 Introduction and Related Work Recent research has explored DNA as a material for self-assembly of nanoscale object