Perceived Quality of Life Is Related to a Healthy Lifestyle and Related Outcomes in Spanish Children and Adolescents: The Physical Activity, Sedentarism, and Obesity in Spanish Study

The PASOS study was funded by Fundación PROBITAS and the Gasol Foundation. Additional funds were received from the FC Barcelona Foundation, Banco Santander, IFA, Vienna, and the Fundación Deporte Joven (no references are applicable). M.M.M., M.R.M., M.G.G., M.M., I.L., J.A.T. and C.B. were funded by CIBEROBN (CB12/03/30038) and H.S. and S.G. by the CIBERESP (CB22/03/00058) of the Institute of Health Carlos III (ISCIII), co-funded by the European Regional Development Fund.[Abstract]: Background: Maintaining a healthy lifestyle is crucial for safeguarding the well-being and quality of life perception, appropriate growth, and development of children and adolescents, while also mitigating the risk of future adult-onset diseases. Objective: To assess associations between perceived quality of life and healthy lifestyle and related outcomes in Spanish children and adolescents. Methods: Cross-sectional analysis of 8–16-year-old children and adolescents (n = 3534) were included in the nationwide study of Physical Activity, Sedentarism, and Obesity in Spanish Youth (PASOS). Data were collected through (1) questionnaires on health-related quality of life (HRQoL), healthy lifestyle outcomes (dietary intake, physical fitness, sleep, and screen time), and (2) anthropometric measurements for weight status assessment. Data were analysed by logistic regression, using the health-related quality of life (HRQoL) as the grouping variable. Results: Participants with a lower HRQoL were those with a lower adherence to the MedDiet and lower achievement of the recommended daily intake of fruit and vegetables. They were also less likely to follow the recommendations for screen time and sleep (with the exception of the weekend) compared to participants with a higher HRQoL. Participants with a lower HRQoL showed a lower healthy weight status and poorer physical fitness than those with a higher HRQoL. Conclusions: Healthy eating habits, healthy weight status (normal weight), appropriate sleep time, physical fitness, and limited screen time play a crucial role in the perceived quality of life in children and adolescentsCIBEROBN; CB12/03/30038CIBERESP; CB22/03/0005

La clase de Educación Física como referencia para identificar actividades vigorosas con acelerometría en niños de 8 y 9 años

The World Health Organization recommends that children and adolescents incorporate vigorous intensity activities but does not define how much vigorous physical activity (VPA) is necessary or what should be the duration of the activity sessions. Objective: To define the proportion of VPA in the most active physical education classes (PEC) to identify vigorous intensity physical activity sessions (i.e., activities). Methods: The PEC of 490 children (8-9 years old) were evaluated using accelerometry. The health-enhancing PEC were identified through the VPA performed and the weight status of the children. The 66.7 percentile of the VPA performed in the PEC by the children was calculated. Results: The average proportion of VPA of the health-enhancing PEC, and that performed by the most active schoolchildren (66.7 percentile) in the total PEC, show similar results. In boys, a VPA proportion of 16.3% and 16.1% was observed, respectively, and in girls 12.0% and 12.8%. Conclusion: The use of bouts of ≥60 minutes with ≥16.7% and 12.5% of VPA in boys and girls, respectively, is proposed to identify vigorous activity sessions with accelerometry.La Organización Mundial de la Salud recomienda que los niños y adolescentes incorporen actividades de intensidad vigorosa, pero no define cuánta actividad física vigorosa (VPA) es necesaria ni cuál debe ser la duración de las sesiones de actividad. Objetivo: Definir la proporción de VPA en las clases de educación física (CEF) más activas para identificar sesiones de actividad física (es decir, actividades) de intensidad vigorosa. Métodos: Se evaluaron mediante accelerometría las CEF de 490 escolares (8-9 años). Se identificaron las CEF consideradas saludablemente activas a través de la VPA realizada y el estado ponderal de los escolares. Se calculó el percentil 66,7 de la VPA realizada en las CEF por los escolares. Resultados: La proporción de VPA media de las CEF saludablemente activas, y la realizada por los escolares más activos (percentil 66,7) en el total de CEF, muestran resultados similares. En los niños se observó una proporción de VPA de 16,3% y 16,1%, y en las niñas del 12,0% y 12,8%, respectivamente. Conclusión: Se propone el uso de bouts de ≥60 minutos con ≥16,7% y 12,5% de VPA en niños y en niñas, respectivamente, para identificar sesiones de actividades vigorosas con acelerometría

Combined Body Mass Index and Waist-To-Height Ratio and Its Association With Lifestyle and Health Factors Among Spanish Children: The PASOS Study

[Abstract] Background and Aims: The World Health Organization recommended simultaneous measurement of body mass index (BMI) and waist circumference (WC) and suggested joint use to predict disease risks. The aim of this study was to assess the prevalence of BMI and waist-toheight ratio (WHtR) categories among Spanish children and adolescents, as well as their associations with several lifestyle factors. Methods: Cross-sectional analysis of 8–16-year-old children and adolescents (n = 3772) were included in the PASOS nationwide representative study. Children/adolescents and their mothers/female caregivers answered a questionnaire on lifestyle and health factors. Child/adolescent anthropometrics were measured. Four combined BMI-WHtR disease risk categories were built. Results: A third of participants showed combined BMI-WHtR categories with high disease risk (12.3% ‘increased risk’, 9.7% ‘high risk’, 14.3% ‘very high risk’). Participants in the ‘very high risk’ group were less likely to be females (odds ratio 0.63; 95% CI: 0.52–0.76) and adolescents (0.60; 95% CI: 0.49–0.72), to practice _60 min/day of moderate-vigorous physical activity (MVPA) (0.73; 95% CI: 0.57–0.93), and to watch <120 min/day of total screen time on weekdays (0.61; 95% CI: 0.49–0.76). Mothers of participants in the ‘very high risk’ group were less likely to have a high educational level, be in the overweight or normal range, have never smoked or were former smokers, and watch <120 min/day of total screen time on weekends. Participants in the ‘increased’ and ‘high risk’ categories had mothers with normal weight and _60 min/day of MVPA. Participants in the ’high risk’ group did not achieve _60 min/day of MVPA and showed lower adherence to the Mediterranean diet. Conclusions: Adherence to a healthy lifestyle in children and adolescents, but also in their mothers/female caregivers during offspring’s childhood and adolescence, is associated with low BMI-WHtR disease risk

Lifestyle behaviors clusters in a nationwide sample of Spanish children and adolescents: PASOS study

[Abstract]: BACKGROUND: Youth is a vulnerable period. To classify lifestyle behaviors and its relationship with health-related outcomes of Spanish children and adolescents. METHODS: Cross-sectional study including 3261 children aged 7.5–17.5 y (52.8% females). Physical activity (PA), screen-time, sleep time, adherence to Mediterranean diet (MD), weight status (WS) by validated methods. Cluster analysis was run considering chronological age. RESULTS: Six clusters were identified: C1: high screen time, low adherence to MD and sleep time (n = 431,13.20%); C2: high WS, medium adherence to MD,high sleep time, and low screen time (n = 466,14.30%); C3: young group with low screen time and high PA, adherence to MD and sleep (n = 537,16.40%); C4: worst profile regarding adherence to MD, PA, WS and sleep time (n = 609,18.70%); C5: low screen time and PA, high sleep time (n = 804,24.70%); C6: high PA and screen time, low WS (n = 414,12.70%). Mean absolute values were statistically different among PA levels, screen and sleep time, adherence to MD, age, and WS (all p < 0.001). CONCLUSIONS: The most prevalent pattern was low levels of PA, MD, and screen time, and high sleep time. The second most prevalent was characterized by very low levels of PA, sleep time, and adherence to MD, and high screen time, and WS in adolescents

Relación entre las horas de sueño y la frecuencia de consumo de alimentos en niños y niñas en Andalucía en 2015

Introducción: La frecuencia de consumo de alimentos y bebidas en los niños depende de diferentes patrones de comportamiento. Objetivos:Evaluar el efecto de la duración del sueño de los niños sobre la frecuencia de consumo de alimentos, y describir las frecuencias de consumo según su estado ponderal y el nivel de educación familiar. Método: Se estudiaron 2721 niños y niñas de 6 a 9 años del Estudio ALADINO 2015 en Andalucía. Se recogieron el número de horas de sueño y la frecuencia semanal de consumo de 24 grupos de alimentos. Se calculó el estado ponderal mediante el índice de masa corporal, con los estándares de crecimiento de la OMS, se recogió el nivel educativo de los padres y madres. Las frecuencias medias de consumo de alimentos se calcularon según la duración del sueño (mayor o menor que la media diaria). Se ajustaron modelos de regresión logística para evaluar las asociaciones independientes de las horas de sueño sobre las frecuencias de consumo de alimentos (variables resultado), ajustando por edad, sexo, nivel de educación de los padres, estado ponderal y disponibilidad de medios de ocio pasivo en la habitación. Resultados: Dormir suficiente número de horas se asocia con mayor probabilidad de consumir fruta (OR:1,23;IC95%:1,06-1,42) y verdura (OR:1,19;IC95%:1,01-1,40), y menor probabilidad de consumir refrescos azucarados (OR:0,80;IC95%:0,67-0,97), zumos con azúcar (OR:0,79;IC95%:0,64-0,99), snacks salados (OR:0,46;IC95%:0,33-0,65), chocolates o caramelos (OR:0,71;IC95%:0,55-0,92), y galletas y bollos (OR:0,70;IC95%:0,58-0,84). El consumo de frutas y verduras medio semanal es mayor en niños sin sobrepeso y en hijos de padres con mayor nivel educativo. Conclusiones: Una duración de sueño adecuada está asociada con mayor consumo de frutas y verduras, y menos alimentos con alta densidad de energía. Mejorar la higiene del sueño es fundamental para mejorar los hábitos alimentarios, y especialmente en niños con sobrepeso, y de menor nivel educativoUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Trends in Adherence to the Mediterranean Diet in Spanish Children and Adolescents across Two Decades.

Unhealthy dietary habits determined during childhood may represent a risk factor to many of the chronic non-communicable diseases (NCDs) in adulthood. Mediterranean Diet (MD) adherence in children and adolescents (8–16 years) living in Spain was investigated using the KIDMED questionnaire in a comparative analysis of two cross-sectional nationwide representative studies: enKid (1998–2000, n = 1001) and PASOS (2019–2020, n = 3540). Taking into account the educational level of pupils, as well as the characteristics of the place of living, a significant association was found between a KIDMED score ≥ 8 (optimal MD adherence) and primary education as well as residency in an area of <50,000 inhabitants, while living in the southern regions was associated with non-optimal MD adherence (p < 0.001). Participants of the 2019–2020 study showed an increase in the consumption of dairy products (31.1% increase), pasta/rice (15.4% increase), olive oil (16.9% increase), and nuts (9.7% increase), as well as a decreased sweets and candies intake (12.6% reduction). In contrast, a significantly lower MD adherence was found when comparing the 2019–2020 (mean ± SE: 6.9 ± 0.04) and the 1998–2000 study (7.37 ± 0.08); p < 0.001), due to less consumption of fish (20.3% reduction), pulse (19.4% reduction), and fruits (14.9% reduction), and an increased intake of commercial goods/pastries or fast-food intake (both 19.4% increase). The lowest adherence was recorded for adolescents also in the most recent study, where 10.9% of them presented a KIDMED score ≤ 3. This study shows that eating habits are deteriorating among Spanish children and adolescents. Such findings point out the urgency of undertaking strong measures to promote the consumption of healthy, sustainable, and non-ultra-processed food, such as those available in an MD, not only at a scientific and academic level, but also at a governmental onePartial funding for open access charge: Universidad de Málag

Combined body mass index and waist-to-height ratio and its association with lifestyle and health factors among Spanish children: the PASOS study

Background and Aims: The World Health Organization recommended simultaneous measurement of body mass index (BMI) and waist circumference (WC) and suggested joint use to predict disease risks. The aim of this study was to assess the prevalence of BMI and waist-to-height ratio (WHtR) categories among Spanish children and adolescents, as well as their associations with several lifestyle factors. Methods: Cross-sectional analysis of 8–16-year-old children and adolescents (n = 3772) were included in the PASOS nationwide representative study. Children/adolescents and their mothers/female caregivers answered a questionnaire on lifestyle and health factors. Child/adolescent anthropometrics were measured. Four combined BMI-WHtR disease risk categories were built. Results: A third of participants showed combined BMI-WHtR categories with high disease risk (12.3% ‘increased risk’, 9.7% ‘high risk’, 14.3% ‘very high risk’). Participants in the ‘very high risk’ group were less likely to be females (odds ratio 0.63; 95% CI: 0.52–0.76) and adolescents (0.60; 95% CI: 0.49–0.72), to practice ≥60 min/day of moderate-vigorous physical activity (MVPA) (0.73; 95% CI: 0.57–0.93), and to watch <120 min/day of total screen time on weekdays (0.61; 95% CI: 0.49–0.76). Mothers of participants in the ‘very high risk’ group were less likely to have a high educational level, be in the overweight or normal range, have never smoked or were former smokers, and watch <120 min/day of total screen time on weekends. Participants in the ‘increased’ and ‘high risk’ categories had mothers with normal weight and ≥60 min/day of MVPA. Participants in the ’high risk’ group did not achieve ≥60 min/day of MVPA and showed lower adherence to the mediterranean diet. Conclusions: Adherence to a healthy lifestyle in children and adolescents, but also in their mothers/female caregivers during offspring’s childhood and adolescence, is associated with low BMI-WHtR disease risk.The PASOS study was funded by Fundación PROBITAS and the Gasol Foundation. Additional funds were received from the Barça Foundation, Banco Santander, IFA, Vienna and the Fundación Deporte Joven (no references are applicable). J.A.T., C.B., M.M.G., and M.d.M.B. were funded by CIBEROBN (CB12/03/30038) of the Institute of Health Carlos III (ISCIII), and co-funded by the European Regional Development Fund

Determinants of adherence to the Mediterranean diet in Spanish children and adolescents: the PASOS study

[Abstract]: A progressive shift away from traditional healthy dietary patterns, such as the Mediterranean diet (MedDiet), has been observed in recent decades. The aim of this study was to assess determinants of optimal adherence to the MedDiet in Spanish children and adolescents. A cross-sec-tional analysis was included in the PASOS nationwide representative study in Spain. Participants were 3607 children and adolescents; 8–16 years old. Primary and secondary outcome measures of weight and height were measured. Adherence to the MedDiet, physical activity, and sedentary behavior in children and adolescents, as well as parental physical activity and dietary habits, were assessed. Optimal adherence to the MedDiet was observed in 45.5% of primary school students and 34.8% of secondary school students (OR: 0.65; 95%CI: 0.56–0.75). Optimal adherence to the MedDiet was higher in children/adolescents meeting daily recommended moderate and vigorous physical activity (OR: 2.39, 95%CI: 1.97–2.89) and in those meeting daily recommended screen time on week-days (OR: 2.05, 95%CI: 1.77–2.38) and weekends (OR: 1.76, 95%CI: 1.48–2.10). Participants with optimal adherence to the MedDiet were more likely to have mothers with a high-level education and high-tercile of SDQS, mothers who never smoked or were former smokers, and mothers who met the recommended physical activity and screen time. It can be concluded that a low prevalence of optimal adherence to the MedDiet was found among current Spanish children and adolescents. Optimal adherence to the MedDiet was associated with reaching the recommendations on physical activity and screen time, with the highest maternal educational level, and healthier maternal life-style

Epidemiología básica. Material docente para prácticas en ciencias de la salud

Material docente teórico práctico para apoyar la enseñanza de la epidemiología. Consta de 4 unidades, cada una de ellas con una introducción teórica y unos ejercicios basados en artículos publicados en inglés en revistas científicas

COVID-19 Severity and Survival over Time in Patients with Hematologic Malignancies: A Population-Based Registry Study

Mortality rates for COVID-19 have declined over time in the general population, but data in patients with hematologic malignancies are contradictory. We identified independent prognostic factors for COVID-19 severity and survival in unvaccinated patients with hematologic malignancies, compared mortality rates over time and versus non-cancer inpatients, and investigated post COVID-19 condition. Data were analyzed from 1166 consecutive, eligible patients with hematologic malignancies from the population-based HEMATO-MADRID registry, Spain, with COVID-19 prior to vaccination roll-out, stratified into early (February–June 2020; n = 769 (66%)) and later (July 2020–February 2021; n = 397 (34%)) cohorts. Propensity-score matched non-cancer patients were identified from the SEMI-COVID registry. A lower proportion of patients were hospitalized in the later waves (54.2%) compared to the earlier (88.6%), OR 0.15, 95%CI 0.11–0.20. The proportion of hospitalized patients admitted to the ICU was higher in the later cohort (103/215, 47.9%) compared with the early cohort (170/681, 25.0%, 2.77; 2.01–3.82). The reduced 30-day mortality between early and later cohorts of non-cancer inpatients (29.6% vs. 12.6%, OR 0.34; 0.22–0.53) was not paralleled in inpatients with hematologic malignancies (32.3% vs. 34.8%, OR 1.12; 0.81–1.5). Among evaluable patients, 27.3% had post COVID-19 condition. These findings will help inform evidence-based preventive and therapeutic strategies for patients with hematologic malignancies and COVID-19 diagnosis.Depto. de MedicinaFac. de MedicinaTRUEFundación Madrileña de Hematología y HemoterapiaFundación Leucemia y LinfomaAsociación Madrileña de Hematología y Hemoterapiapu