Management and Good Laboratory Practice Central Animal Facility

This report describes the realisation and implementation of working procedures in compliance with Good Laboratory Practice, as performed by the Central Animal Facility of Division II Pharmacology and Toxicology. This report froms a basis for a quality system with the pivot aim to meet Sterlab requirements.RIV

Management and Good Laboratory Practice at the Division Biological Evaluation of Drug effects of the Central Animal Laboratory

The department BES (Biological Evaluation of Drug Effects) carries out animal studies for RIVM laboratories, whose commitment to GLP makes it necessary for BES also to comply with GLP. Compliance is assured by means of a quality system laid down in a quality handbook quaranteeing the consistent quality of the department products. The elements of the BES quality system are documented in this report under the following headings: - quality targets and management organisation - survey of areas of competence and of stoff qualifications - equipment inventory - goods and services available - standard operating procedures. Furthermore a general servey is presented of those co-operative arrangements necessary for optimal departmental organization.RIV