33 research outputs found
An efficient shoot regeneration system for medicinally important Elephantopus scaber Linn.
Full text linkOrganogenesis from in vitro-derived leaf and internode explants of Hoya wightii ssp. palniensis -a vulnerable species of Western Ghats
Full text linkADVERSE DRUG REACTIONS AMONG PATIENTS IN DEPARTMENT OF MEDICINE A TERTIARY CARE TEACHING HOSPITAL , KOLLAM
No full textBackground: Pharmacovigilance practices are still in infancy in India, more so in South India. ADRs are often under reported probably due to the patient overload, insufficient staff , unawareness of methods of ADR reporting, over the counter medications etc. The risks are on the higher spectrum in adults and elderly due to the association of comorbidities, self medication, combination of indigenous systems of medicines and modern medicine and so on. The present study was carried out with the objectives to analyse the adverse drug reactions among patients in the general medicine department , Government Medical College, Kollam to determine the prevalence and nature of adverse drug reactions and to assess the causality, severity and preventability of the ADRs.
Design and Methods:
In this cross sectional study done in Department of Medicine , Government medical college, Kollam , 1000 patients of either sex were analysed using CDSCO ADR reporting forms and the approved scales for causality, severity and preventability.
Results:
Among 1000 patients studied, the prevalence of ADRs were 7.6%. Most common system involved were dermatological (41%) followed by cardiovascular (18%) and gastrointestinal and neurology (16 % each). Majority of the ADRs came under probable (48.7%) with a Naranjo score of 5 (40.8%), of moderate severity (65.8%) and not preventable (71.1%).
Conclusion:
ADRs pose a major problem needing hospital stay or prolonging the duration of stay. Developing an ongoing adverse drug reaction reporting system with continuous motivation and creating awareness among the healthcare professionals for reporting suspected adverse drug reactions will help to continue reporting and improving the patient safety. Improved communication of health care professionals with the pharmacovigilance centres should be promoted for better patient healthcare.
Keywords : Adverse drug reaction, Medicine, Pharmacovigilance, ADR reporting, Patient safet
In vitro regeneration approaches for restoration of Ceropegia mohanramii—an endemic and critically endangered asclepiad
No full textIn vitro regeneration, production, and storage of artificial seeds in Ceropegia barnesii, an endangered plant
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Combinatorial Approach Through In Vitro Regeneration and Phytochemical Profiling of Ceropegia media (Huber) Ans.: A Potential Way Forward in the Conservation of an Endangered Medicinal Plant from the Western Ghats in India
No full textAn efficient micropropagation system for Tylophora indica: an endangered, medicinally important plant
No full textAn efficient in vitro regeneration of Ceropegia noorjahaniae: an endemic and critically endangered medicinal herb of the Western Ghats
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