93 research outputs found
Affect and Performance across Double-Elimination Tournaments: A Field Study of Super Smash Bros Competitors
Esports provide an opportunity to study the relationship between affect and competitive performance in highly structured yet ecologically valid environments. In this study, we examine self-ratings of affect, performance pressure, and self-other focus within 90 competitors over the course of 327 sets of games in national-level Super Smash Bros tournaments. Within competitors, higher arousal is associated with loss in the next tournament set, even when controlling for known predictors of outcome such as competitor and opponent skill levels, time, and the random effect of competitor. Mediation analyses suggest that perceived performance pressure does not cause increased arousal leading to loss, nor does increased arousal lead to elevated self-focus. In all, esports competitors may benefit from emotion regulation skills training to down-regulate arousal and optimize performance. To conclude we consider the role of double-elimination tournament structure in shaping the affective experiences of competitors
Do dimensional psychopathology measures relate to creative achievement or divergent thinking?
11 pagesPrevious research provides disparate accounts of the putative association between creativity and psychopathology, including schizotypy, psychoticism, hypomania, bipolar disorder, ADHD, and autism spectrum disorders. To examine these association, healthy, non-clinical participants completed several psychopathology-spectrum measures, often postulated to associate with creativity: the Schizotypal Personality Questionnaire, the Psychoticism scale, the Personality Inventory for DSM-5, the Hypomanic Personality Scale, the Attention Deficit/Hyperactivity Disorder scale, the Beck Depression Inventory, and the Autism-Spectrum Quotient. The goal of Study 1 was to evaluate the factor structure of these dimensional psychopathology measures and, in particular, to evaluate the case for a strong general factor(s). None of the factor solutions between 1 and 10 factors provided a strong fit with the data based on the most commonly used metrics. The goal of Study 2 was to determine whether these psychopathology scales predict, independently, two measures of creativity: 1. a measure of participants' real-world creative achievements, and 2. divergent thinking, a laboratory measure of creative cognition. After controlling for academic achievement, psychoticism and hypomania reliably predicted real-world creative achievement and divergent thinking scored with the consensual assessment technique. None of the psychopathology-spectrum scales reliably predicted divergent thinking scored with the manual scoring method. Implications for the potential links between several putative creative processes and risk factors for psychopathology are discussed
Heat flow model for pulsed laser melting and rapid solidification of ion implanted GaAs
Some of the authors thank for the support of the Center for Nanoscale Systems (CNS) at Harvard University is acknowledged. Harvard-CNS is a member of the National Nanotechnology Infrastructure Network (NNIN), which is supported by the National Science Foundation under NSF award No. ECS-0335765. K. M. Yu and J. W. Beeman were supported by the Director, Office of Science, Office of Basic Energy Sciences, Materials Sciences and Engineering Division, of the U.S. Department of Energy under Contract No. DE-AC02-05CH11231.Some of the authors thank for the support of the Center for Nanoscale Systems (CNS) at Harvard University is acknowledged. Harvard-CNS is a member of the National Nanotechnology Infrastructure Network (NNIN), which is supported by the National Science Foundation under NSF award No. ECS-0335765. K. M. Yu and J. W. Beeman were supported by the Director, Office of Science, Office of Basic Energy Sciences, Materials Sciences and Engineering Division, of the U.S. Department of Energy under Contract No. DE-AC02-05CH11231
Triggering Receptor Expressed on Myeloid Cell 2 R47H Exacerbates Immune Response in Alzheimer\u27s Disease Brain.
The R47H variant in the microglial triggering receptor expressed on myeloid cell 2 (TREM2) receptor is a strong risk factor for Alzheimer\u27s disease (AD). To characterize processes affected by R47H, we performed an integrative network analysis of genes expressed in brains of AD patients with R47H, sporadic AD without the variant, and patients with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), systemic disease with early-onset dementia caused by loss-of-function mutations in TREM2 or its adaptor TYRO protein tyrosine kinase-binding protein (TYROBP). Although sporadic AD had few perturbed microglial and immune genes, TREM2 R47H AD demonstrated upregulation of interferon type I response and pro-inflammatory cytokines accompanied by induction of NKG2D stress ligands. In contrast, PLOSL had distinct sets of highly perturbed immune and microglial genes that included inflammatory mediators, immune signaling, cell adhesion, and phagocytosis. TREM2 knockout (KO) in THP1, a human myeloid cell line that constitutively expresses the TREM2- TYROBP receptor, inhibited response to the viral RNA mimetic poly(I:C) and phagocytosis of amyloid-beta oligomers; overexpression of ectopic TREM2 restored these functions. Compared with wild-type protein, R47H TREM2 had a higher stimulatory effect on the interferon type I response signature. Our findings point to a role of the TREM2 receptor in the control of the interferon type I response in myeloid cells and provide insight regarding the contribution of R47H TREM2 to AD pathology
Overview and status of EXCLAIM, the experiment for cryogenic large-aperture intensity mapping
The EXperiment for Cryogenic Large-Aperture Intensity Mapping (EXCLAIM) is a
balloon-borne far-infrared telescope that will survey star formation history
over cosmological time scales to improve our understanding of why the star
formation rate declined at redshift z < 2, despite continued clustering of dark
matter. Specifically,EXCLAIM will map the emission of redshifted carbon
monoxide and singly-ionized carbon lines in windows over a redshift range 0 < z
< 3.5, following an innovative approach known as intensity mapping. Intensity
mapping measures the statistics of brightness fluctuations of cumulative line
emissions instead of detecting individual galaxies, thus enabling a blind,
complete census of the emitting gas. To detect this emission unambiguously,
EXCLAIM will cross-correlate with a spectroscopic galaxy catalog. The EXCLAIM
mission uses a cryogenic design to cool the telescope optics to approximately
1.7 K. The telescope features a 90-cm primary mirror to probe spatial scales on
the sky from the linear regime up to shot noise-dominated scales. The telescope
optical elements couple to six {\mu}-Spec spectrometer modules, operating over
a 420-540 GHz frequency band with a spectral resolution of 512 and featuring
microwave kinetic inductance detectors. A Radio Frequency System-on-Chip
(RFSoC) reads out the detectors in the baseline design. The cryogenic telescope
and the sensitive detectors allow EXCLAIM to reach high sensitivity in spectral
windows of low emission in the upper atmosphere. Here, an overview of the
mission design and development status since the start of the EXCLAIM project in
early 2019 is presented.Comment: SPIE Astronomical Telescopes + Instrumentation. arXiv admin note:
substantial text overlap with arXiv:1912.0711
Experiment for cryogenic large-aperture intensity mapping: instrument design
The experiment for cryogenic large-aperture intensity mapping (EXCLAIM) is a balloon-borne telescope designed to survey star formation in windows from the present to z = 3.5. During this time, the rate of star formation dropped dramatically, while dark matter continued to cluster. EXCLAIM maps the redshifted emission of singly ionized carbon lines and carbon monoxide using intensity mapping, which permits a blind and complete survey of emitting gas through statistics of cumulative brightness fluctuations. EXCLAIM achieves high sensitivity using a cryogenic telescope coupled to six integrated spectrometers employing kinetic inductance detectors covering 420 to 540 GHz with spectral resolving power R = 512 and angular resolution ≈4 arc min. The spectral resolving power and cryogenic telescope allow the survey to access dark windows in the spectrum of emission from the upper atmosphere. EXCLAIM will survey 305 deg2 in the Sloan Digital Sky Survey Stripe 82 field from a conventional balloon flight in 2023. EXCLAIM will also map several galactic fields to study carbon monoxide and neutral carbon emission as tracers of molecular gas. We summarize the design phase of the mission
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