55 research outputs found
1st Congress of the Croatian Society for Neurovascular Disorders, Croatian Medical Association, and 2nd Congress of the Croatian Society for Stroke Prevention
Healthy lifestyle and prevention of stroke postgraduate course organizers inter-university center Dubrovnik, Academy of Medical Sciences of Croatia, and Croatian Stroke Society
25th Anniversary of Laboratory of Cerebrovascular Diagnostics, University Department of Neurology, Sestre milosrdnice University Hospital, Zagreb, Croatia
Osnove neuropsihologije i neurologije ponaŔanja (The Basis of Neuropsychology and Behavioral Neurology)
Recovery of Recurrent Transient Neurogenic Stuttering due to Functional Neuroplasticity
Although epilepsy symptoms are well established, there are only several described cases of post seizure speech fluency impairments. Epileptic activity may interfere with speech but speech impairments have the ability to recover because of neural plasticity that has been widely investigated in epilepsy popula- tion. In the available literature there is only one case report of transient neurogenic stuttering de- scribed. In this case report we describe a recovery of a 33-year-old male patient with recurrent transient neurogenic stuttering after focal idiopathic seizures due to functional neuroplasticity
Cholesterol ā The Lower the Better?
Odnos razine serumskoga kolesterola i rizika za moždani udar složen je, opreÄan i prisutan u Å”irokom rasponu serumskih razina ukupnoga kolesterola, LDL-a i HDL-a. RazliÄite tvari razliÄitog mehanizma djelovanja, ali s istim ciljem snižavanja razine serumskog LDL-a, statini, ezetimib i PCSK9 inhibitori snizuju incidenciju ishemijskoga moždanog udara, Å”to izravno upuÄuje na uzroÄno-posljediÄnu povezanost snižavanja serumske razine LDL-a i sprjeÄavanja nastanka moždanog udara. Upozorenja o moguÄemu poveÄanom riziku za hemoragijski moždani udar na temelju rezultata SPARCL istraživanja i statistiÄki neznaÄajno poveÄanje rizika naznaÄeno u rezultatima IMPROVE-IT, FOURIER i Cholesterol Treatment Trialist metaanalize moguÄe upuÄuju kako bi znaÄajno snižavanje LDL-C-a moglo uzrokovati hemoragijski moždani udar u posebno ranjivoj podskupini bolesnika, osobito u žena i bolesnika s loÅ”e reguliranom arterijskom hipertenzijom. S obzirom na to da je hemoragijski moždani udar u usporedbi s ishemijskim moždanim udarom rijedak, zabrinutost zbog moguÄega poveÄanog rizika za hemoragijski moždani udar ne smije zasjeniti dobrobit od primjene lijekova za snižavanje LDL-C-a i boljeg ishoda vaskularnih bolesti u bolesnika lijeÄenih ovom terapijom. Nužno je utvrditi stratifikaciju razliÄitih kategorija bolesnika s obzirom na riziÄne Äimbenike, kao i s obzirom na spol i životnu dob, te primijeniti individualan pristup i personalizaciju lijeÄenja, kako u primarnoj tako i u sekundarnoj prevenciji moždanog udara.The correlation between serum cholesterol levels to stroke risk is complex and contradictory, and exists in a whole scope of serum levels of total cholesterol, LDL and HDL. Different substances with different action mechanisms, but with a shared goal of lowering serum LDL levels, statins, ezetimibe and PCSK9 inhibitors, reduce the incidence of IS (ischemic stroke), which directly suggests a cause-and-effect link between lowering serum LDL levels and preventing stroke. Warnings of a possible increased risk of hemorrhagic stroke (HS) based on the results of the SPARCL study and a statistically insignificant increase in risk indicated in the IMPROVE-IT and FOURIER results, as well as Cholesterol Treatment Trialist meta-analyses may suggest that a significant reduction in LDL-C could cause HS in a particularly vulnerable subgroup of patients, especially in women and patients with poorly regulated arterial hypertension. As HS is rare compared to IS, concerns about potential increased risk of HS should not overshadow the benefits of LDL-C-lowering drugs and better vascular effects in patients treated with this therapy. It is necessary to determine the stratification of different patient categories in terms of risk factors as well as gender and age, and apply an individual approach and personalised treatment in both primary and secondary prevention of stroke
Recovery of Recurrent Transient Neurogenic Stuttering due to Functional Neuroplasticity
Although epilepsy symptoms are well established, there are only several described cases of post seizure speech fluency impairments. Epileptic activity may interfere with speech but speech impairments have the ability to recover because of neural plasticity that has been widely investigated in epilepsy popula- tion. In the available literature there is only one case report of transient neurogenic stuttering de- scribed. In this case report we describe a recovery of a 33-year-old male patient with recurrent transient neurogenic stuttering after focal idiopathic seizures due to functional neuroplasticity
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