12 research outputs found

    PG119 PATIENT RELEVANT ASPECTS OF DIAGNOSTIC QUESTIONNAIRES AND THEIR SUBSCALES IN GASTRO-OESOPHAGEAL REFLUX DISEASE (GERD)

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    Analysis of the acoustic characteristics and optimization potential of road surfaces - One focus within the project "Quiet Road Traffic 3"

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    The development of silent road surfaces demands a detailed analysis of the tire/road interaction mechanisms basically determining the noise radiation of flowing traffic. Such an analysis is of significant importance to identify and characterize the relevant effects which affect the acoustic properties of the pavements. This paper reviews the approaches pursued within the interdisciplinary research project "Quiet Road Traffic 3" including an adequate expansion of the SPERoN model for the quantitative prediction of the tire/road noise. A variety of novel materials and road constructions is investigated to validate the model, to design optimized pavements, and to explore their application potential. The practical use of the results will be finally checked by implementing and monitoring test tracks. The research activities cover asphalt as well as concrete construction techniques and focus in particular on measures to reduce the noise nuisance in agglomerations. In total, the approaches within the project "Quiet Road Traffic 3" are intended to lower the road traffic noise level by 4 to 6 dB(A) as compared to the current state of the art

    Analysis of the acoustic characteristics and optimization potential of road surfaces - One focus within the project "Quiet Road Traffic 3"

    No full text
    The development of silent road surfaces demands a detailed analysis of the tire/road interaction mechanisms basically determining the noise radiation of flowing traffic. Such an analysis is of significant importance to identify and characterize the relevant effects which affect the acoustic properties of the pavements. This paper reviews the approaches pursued within the interdisciplinary research project "Quiet Road Traffic 3" including an adequate expansion of the SPERoN model for the quantitative prediction of the tire/road noise. A variety of novel materials and road constructions is investigated to validate the model, to design optimized pavements, and to explore their application potential. The practical use of the results will be finally checked by implementing and monitoring test tracks. The research activities cover asphalt as well as concrete construction techniques and focus in particular on measures to reduce the noise nuisance in agglomerations. In total, the approaches within the project "Quiet Road Traffic 3" are intended to lower the road traffic noise level by 4 to 6 dB(A) as compared to the current state of the art

    Generation of a human induced pluripotent stem cell line (HMGUi002-A) from a healthy male individual.

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    Induced pluripotent stem cells (iPSCs) can be used to generate different somatic cell types in vitro, including insulin-producing pancreatic beta-cells. Here, we have generated iPSCs from a healthy male individual using an episomal reprogramming method. The resulting iPSCs are integration-free, have a normal karyotype and are pluripotent in vitro and in vivo. Furthermore, we show that this iPSC line can be differentiated into pancreatic lineage cells. Taken together, this iPSC line will be useful to test differentiation protocols towards beta-cell as well as other cell types and will also serve as a control for drug development and disease modelling studies

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