843 research outputs found
Letter from William Bebb to James B. Finley
Gov. Bebb has just received Finley\u27s letter of the 21st. The evidence of Piles\u27 repentance and reformation seems to be strong and he regrets that his attention was not specially directed to Piles\u27 case before he left Columbus. He will return about the 10th of May and will embrace the earliest opportunity to examine the case. Abstract Number - 1071https://digitalcommons.owu.edu/finley-letters/2055/thumbnail.jp
The emerging role of nimotuzumab in the treatment of non-small cell lung cancer
Current non-small cell lung cancer (NSCLC) chemotherapy and radiotherapy regimens, although showing definite survival benefit, still leave patients with a disappointing 15% 5-year overall survival rate. Because of the need to improve traditional outcomes, research has focused on identifying specific tumorigenic pathways that may serve as therapeutic targets. The most successful strategies to date are those aimed at the epidermal growth factor receptor (EGFR), which is found to be upregulated in 40%–80% of NSCLC. Several tyrosine kinase inhibitors and monoclonal antibodies (mAbs) have been developed that inhibit the EGFR receptor and have demonstrated clinical benefit in trials as single agents and in combination regimens. Here we discuss one such agent, the mAb nimotuzumab, the background of its development, its clinical experience in NSCLC thus far, and the rationale for expanding its use to other NSCLC treatment settings
Lysimachia quadriflora Sims
https://thekeep.eiu.edu/herbarium_specimens_byname/6553/thumbnail.jp
Phyla lanceolata (Michx.) Greene
https://thekeep.eiu.edu/herbarium_specimens_byname/19024/thumbnail.jp
Implementing Systems Engineering Practices to the Zips Aero Design Team
The Zips Aero Design Team is a college sponsored design team that competes each year through the American Institute of Aeronautics and Astronautics (AIAA) Design Build Fly (DBF) competition. The rules generally consist of 3 differing flight missions and a ground mission, with overarching requirements such as size, takeoff distance, and battery limitations. A complex set of rules such as these is meant to be difficult for even the best of teams to master, especially without proper organization and project management. This senior design report outlines the benefits of implementing systems engineering to the Zips Aero Design Team, through multiple avenues such as requirements management, design reviews, model-based systems engineering, manufacturing optimization, and more. The primary goal of this senior design project is to improve the functionality and culture of the Zips Aero Design Team through systems engineering integration, with a secondary goal of improving upon the AIAA DBF technical report score and competition final score as compared to previous years. Through implementation of these systems engineering practices, comments have been received on the 2022-2023 season being the team’s most successful year in many seasons. Overall, systems engineering has made a very positive impact on the Zips Aero Design Tea
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