Urinary Calculi: Review of Classification Methods and Correlations with Etiology

Current physical and chemical methods available for urinary stones analysis are critically reviewed. No one method is sufficient to provide all the clinically useful information on the structure and composition of the stones. We show that a combination of refined morphological and structural examination of stone with optical microscopy, complemented by compositional analysis using infrared spectroscopy of the core, cross-section and surface of calculi, provides a precise and reliable method for identifying the structure and crystalline composition, and permits quantification of stone components while being highly cost effective. Using such morphoconstitutional studies leads to a classification of urinary stones in seven distinctive types and twenty-one subtypes among monohydrate (whewellite) and dihydrate (weddellite) calcium oxalates, phosphates, uric acid, urates, protein, and cystine calculi. Furthermore, all of the recognized sub-types exhibit correlations with specific pathophysiologic conditions. We conclude that such morphoconstitutional refined analysis and classification of urinary calculi is of interest to properly identify the type of stone disease and provides clues to etiopathogeny

Methodological Aspects of Spontaneous Crystalluria Studies in Calcium Stone Formers

Despite nearly a half-century of study, the clinical value of spontaneous crystalluria (Cx) examinations in calcium stone formers (CaSF) is still uncertain. The analytical complexity of urine particle study is largely responsible for this situation. As a result, there is no consensus regarding technical methods in Cx with several techniques for urine sampling and three different instruments currently used for particle study, namely, particle counting (PC), light microscopy (LM) and petrographic microscopy (PM). In this work, we first examined urine sampling and instrument methods regarding their appropriateness for Cx studies. Then we performed a comparative analysis of Cx studies in CaSF. Despite many technical and clinical discrepancies, several studies agree that the frequency of all particles and of the weddellite and whewellite calcium oxalate (CaOx) crystalline phases are increased in CaSF as compared to normal subjects (NS). Particle sizes and aggregation ratio are also often increased. Altogether, these results reinforce the need for an efficient method for Cx studies in these patients. Examining each technique leads us to conclude that most particle parameters can be studied by direct LM observation of freshly voided urine samples, i.e., urine samples without any separation steps. For clinical applications, several examinations should be performed, first to define the specific Cx characteristics in a patient, then for the study of treatment efficiency on Cx control, and finally, during the patient follow-up. Due to Cx variability in each patient, the frequency of Cx examinations during each phase needs to be determined in long-term comparative prospective studies of CaSF

Developing a predictive environment-based model for mapping biological soil crust patterns at the local scale in the Sahel

Several studies have demonstrated the great range of possibilities offered by remote sensing in identifying, estimating and mapping biological soil crust (BSC) patterns, i.e. a feature recognised to play major functions in drylands. However those techniques are suitable mainly where BSC patterns are abundant ( > 30%) and vegetation cover low ( 75%. Predicted values were obtained with an overall accuracy of 77.7% (kappa = 0.54), classifying the model as good and discriminant. This work is the first step in assessing the local scale ecological functions of BSC. Further work is needed for extrapolation at the regional scale in order to provide a useful tool for ecological surveys and for predictions of soil surface dynamics related to global changes in dryland areas

A predictive model of spatial distribution of biological soil crust in the Sahel from local to regional scale [abstract]

EGU.European Geosciences Union General Assembly, Vienne, AUT, 22-/04/2012 - 27/04/201