African Religious Integration In Florida During The First Spanish Period

This thesis is an examination of the unique conditions for African-descended slaves in St. Augustine, Florida, during the First Spanish Period. St. Augustine was an important garrison at a remote point in the Spanish Empire at the edge of a hostile frontier. As such, economics were less a priority than defense. Slaves, therefore, received different treatment here than in English colonies or even other Spanish colonies. Due to the threat of Protestantism, religious adherence was more important as a test of loyalty than ethnicity and slaves and freed-people were able to integrate better than in other Spanish holdings. In order to explore this integration, the meticulous records of the St. Augustine clergy are used. Infant baptism rates are used to show the influence of Spanish culture as well as at least a semblance of adherence on the part of African-descended people. The baptism of adults, meanwhile, and the role of the godparent are examined to show integration and the complex nature of this unique religious phenomenon

Neuropsychological function in patients with a single gene mutation associated with autosomal dominant nocturnal frontal lobe epilepsy

Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) is a nonlesional condition associated with mutation of the gene coding for the α4 nicotinic acetylcholine receptor (nAChR). The nAChR modulates aspects of memory and attention. We examined the neuropsychological phenotype of ADNFLE, with a particular emphasis on understanding the impact on frontal lobe functions. We used standard clinical tests as well as focused measures of frontal lobe function in a well-defined group of patients with ADNFLE. Their performance was compared with that of a group of age-, sex-, and education-matched control participants. Patients with ADNFLE showed impairments on tasks requiring cognitive flexibility against a background of well-preserved intellectual abilities. In accord with existing research, verbal memory impairments were identified in the patient group; the level of impairment on these tasks correlated with disease-related factors. In our study of ADNFLE associated with one mutation, cognitive flexibility appears to be the core cognitive deficit