Search for eccentric black hole coalescences during the third observing run of LIGO and Virgo

Despite the growing number of confident binary black hole coalescences observed through gravitational waves so far, the astrophysical origin of these binaries remains uncertain. Orbital eccentricity is one of the clearest tracers of binary formation channels. Identifying binary eccentricity, however, remains challenging due to the limited availability of gravitational waveforms that include effects of eccentricity. Here, we present observational results for a waveform-independent search sensitive to eccentric black hole coalescences, covering the third observing run (O3) of the LIGO and Virgo detectors. We identified no new high-significance candidates beyond those that were already identified with searches focusing on quasi-circular binaries. We determine the sensitivity of our search to high-mass (total mass M>70 M⊙) binaries covering eccentricities up to 0.3 at 15 Hz orbital frequency, and use this to compare model predictions to search results. Assuming all detections are indeed quasi-circular, for our fiducial population model, we place an upper limit for the merger rate density of high-mass binaries with eccentricities 0<e≤0.3 at 0.33 Gpc−3 yr−1 at 90\% confidence level

Ultralight vector dark matter search using data from the KAGRA O3GK run

Among the various candidates for dark matter (DM), ultralight vector DM can be probed by laser interferometric gravitational wave detectors through the measurement of oscillating length changes in the arm cavities. In this context, KAGRA has a unique feature due to differing compositions of its mirrors, enhancing the signal of vector DM in the length change in the auxiliary channels. Here we present the result of a search for U(1)B−L gauge boson DM using the KAGRA data from auxiliary length channels during the first joint observation run together with GEO600. By applying our search pipeline, which takes into account the stochastic nature of ultralight DM, upper bounds on the coupling strength between the U(1)B−L gauge boson and ordinary matter are obtained for a range of DM masses. While our constraints are less stringent than those derived from previous experiments, this study demonstrates the applicability of our method to the lower-mass vector DM search, which is made difficult in this measurement by the short observation time compared to the auto-correlation time scale of DM

Myotonic dystrophy (Steinert disease): A morphologic and biochemical hair study

Background: Myotonic dystrophy is a systemic genetic disorder, with dominant transmittance, it is characterized by generalized progressive muscular abnormality. Although frontoparietal alopecia is one of the most common symptoms in myotonic dystrophy, it has not received much attention. Methods: We examined 25 subjects from two families: 10 patients were affected by Steinert disease and 15 were not. The various morphologic and biochemical hair alteratiOnS are reported. Results: All investigated subjects (affected or not) presented the same type of morphologic and biochemical hair alterations. Conclusions: These findings could be used to construct a hypothesis to explain the cause of the disease

Sediment composition, provenance, and Holocene paleoenvironmental evolution of the Southern Po River coastal plain (Italy)

Geochemistry, sediment provenance, and the Holocene paleoenvironmental evolution of the Southern Po River coastal plain (Italy) were examined based on the geochemical analysis of 279 sediment samples from 35 cores. The Holocene succession is subdivided into four major facies associations: back-barrier, transgressive barrier, shallow-marine, and beach-ridge deposits. Bulk chemical composition shows remarkable differences between facies associations, and the poly-modal behavior in the related frequency curves suggests distinct sources of sediment. Using MgO and Ni as geochemical tracers, changes in sediment provenance were assessed with the aim to reconstruct the Holocene paleoenvironmental evolution of the area. The Po River and the Apenninic rivers represented the main sources of sediment during the early stages of transgression and highstand sea-level conditions, whereas transgressive barrier and early shallow-marine facies associations exhibit a clear North Adriatic river (eastern Alpine) provenance. The Holocene paleoenvironmental evolution of the study area, between about 10 ky and the present, indicates the presence of a bypass zone in front of the Po River mouth between 9 and 6 ky BP. At that time, sediment supplied by the North Adriatic rivers was transported southward by the longshore drift, bypassed the weak Po River influx and accumulated close to the Apennines. Comparison between Holocene facies associations and current back-barrier and shallow-marine sediments confirms that the present-day basin circulation is similar to the one that acted during the last episode of sea-level rise

Capillaroscopy: a new application for the evaluation of vascular side-effects induced by chemotherapy

Background: Cancer survivors are rising up, but this better survival is accompanied by possible treatments side-effects. In particular, cardiovascular effects are commonly reported, even if vascular damage is not necessarily connected to clinical manifestations. Periungual microcyrcle evaluation through capillaroscopy could identify asymptomatic patients with high risk of cerebro-cardio- vascular disease. The aim of this pivotal study is to evaluate videocapillaroscopy in patients who undergo chemotherapy, in order to understand if it could represent in future a prognostic tool to predict the risk of cardio-cerebro-vascular events. Methods: We conducted an open-label, uncontrolled study. Patients affected by solid tumors were enrolled. Each subject underwent a clinical evaluation and a videocapillaroscopic examination. Results: We selected 25 patients. Mean age was 55.48 years. Time interval between the start of chemotherapy and capillaroscopy: average 41 months. From our analysis it emerges that ectasia and hemorrhages could be a possible markers of capillary insult caused by chemotherapy. Conclusions: Our study shows the presence of capillaroscopic features that may be peculiar in chemotherapy-induced endothelial damage. The individuation of capillaroscopic alteration specific for chemotherapy-induced endothelial injury could be an important tool to identify patients with high cardiovascular risk