Final Report of the Phase III Archaeological Investigations at the Dr. Upton Scott House (18AP18), Annapolis, Anne Arundel County, Maryland, 1998-1999

In the summers of 1998 and 1999, the Archaeology in Annapolis project carried out archaeological investigation at the eighteenth century Dr. Upton Scott House site (18AP18)located at 4 Shipwright Street in the historic district of Annapolis, Anne Arundel County, Maryland. The Upton Scott House is significant as one of only a few Georgian houses with remnants of its original plantation-inspired landscape still visible (Graham 1998:147). Investigation was completed in agreement with the owners of the historic property, Mr. and Mrs. Paul Christian, who were interested in determining the condition and arrangement of Dr. Upton Scott’s well-documented pleasure gardens. Betty Cosans’ 1972 Archaeological Feasibility Report, the first real archaeological study of the Upton Scott House site, guided the research design and recovery efforts. Cosans determined that testing and survey in the back and side yards of the Scott property would yield important information on the use and history of the property, including that of Scott’s famous gardens. Excavation units and trenches were placed within three separate areas of backyard activity on the site which included Area One: extant brick stables in the southwest of the property; Area Two: the brick foundations of a small outbuilding located in the northwest area of the site; and Area Three: the area of Scott’s formal gardens. The research design included an interest in recovering evidence of African-American spiritual practice and domestic life at the site. Also of significant importance was an analysis of Scott’s garden beds, concerning the order and layout. Also sought was an understanding of the change in perception and use of the backyard by the various owners of the property

Some demographic characteristics of an autopsied population

The ways in which a series of autopsied hospital patients may or may not differ from other hospital deaths and from deaths in the general population are necessarily of concern to investigators conducting studies based upon postmortem observations, as well as to those concerned with epidemiological and sociological aspects of hospitalization and autopsy. In an effort to investigate this problem, certain demographic characteristics of a population of adults autopsied during a 4-year period at a large general teaching hospital were examined. This population was compared with its parent population, all deaths that occurred at this hospital, and with the population from which the latter, in turn, was derived, all deaths in the northeastern metropolitan county served by this hospital. The variables analyzed were age, sex, nativity, race, marital status, size of residence, place, religious preference, and cause of death.The composition of the autopsied population indicated that it had been significantly affected by various selective factors. Age exhibited perhaps the most striking effects: as age at death decreased, the likelihood increased that a person who died in this county had been hospitalized and autopsied at the institution under study. This trend was especially marked among females. Subsequent analyses were therefore adjusted to control the effects of age and sex.Certified cause of death also was found to be highly subject to selective factors. In particular, the proportions of all deaths in the county from heart disease that occurred and were autopsied at this hospital were strikingly smaller than those of any other of the causal categories employed.With respect to religion, there was suggestive evidence that deceased hospital patients who had indicated a Jewish preference were considerably less likely to be autopsied than those who had designated a Protestant group. Catholics appeared somewhat less likely to be autopsied than Protestants.Other differences found were that the foreign-born were somewhat more likely to be hospitalized at this institution than the native-born, but less likely to be autopsied. Negroes, the divorced, and residents of other states and of places in the state with less than 10,000 inhabitants were more likely to be hospitalized and autopsied at this hospital than those in other categories of race, marital status, and place of residence.In general, deaths at the hospital differed more from deaths in the general population than the autopsied deaths differed from all deaths at the hospital.These findings indicate a few of the kinds of selection that may be found in the composition of autopsied and hospital death populations. They are interpreted as pointing up the need for giving special attention to the effects of selective factors on populations used in autopsy-based research. More specifically, it is hoped that these analyses may illustrate a practicable means by which the extent of selection in a particular autopsy series may be gauged. Usually it should be possible to examine the distributions of variables that may be relevant to a particular study, to compare these with what is known regarding their distributions in other populations, and to control, by special analyses, the effects of such variables as appear to require this with at least sufficient precision to permit extending tentative inferences beyond the immediate study material. Where a unique contribution can be provided by postmortem observations, their use appears justified in the study of many disease problems with the qualification that appropriate care be given to the exploration and control of potential sources of bias.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/32070/1/0000114.pd

Inter-scan reproducibility of coronary calcium measurement using Multi Detector-Row Computed Tomography (MDCT)

Purpose: To assess inter-scan reproducibility of coronary calcium measurements obtained from Multi Detector-Row CT (MDCT) images and to evaluate whether this reproducibility is affected by different measurement protocols, slice thickness, cardiovascular risk factors and/or technical variables. Design: Cross-sectional study with repeated measurements. Materials and methods: The study population comprised 76 healthy women. Coronary calcium was assessed in these women twice in one session using 16-MDCT (Philips Mx 8000 IDT 16). Images were reconstructed with 1.5 mm slice thickness and 3.0 mm slice thickness. The 76 repeated scans were scored. The Agatston score, a volume measurement and a mass measurement were assessed. Reproducibility was determined by estimation of mean, absolute, relative difference, the weighted kappa value for agreement and the Intra-class correlation coefficient (ICCC). Results: Fifty-five participants (72.4%) had a coronary calcification of more than zero in Agatston (1.5 mm slice thickness). The reproducibility of coronary calcium measurements between scans in terms of ranking was excellent with Intra-class correlation coefficients of >0.98, and kappa values above 0.80. The absolute difference in calcium score between scans increased with increasing calcium levels, indicating that measurement error increases with increasing calcium levels. However, no relation was found between the mean difference in scores and calcium levels, indicating that the increase in measurement error is likely to result in random misclassification in calcium score. Reproducibility results were similar for 1.5 mm slices and for 3.0 mm slices, and equal for Agatston, volume and mass measurements. Conclusion: Inter-scan reproducibilility of measurement of coronary calcium using images from MDCT is excellent, irrespective of slice thickness and type of calcium parameter

Differences in carotid arterial morphology and composition between individuals with and without obstructive coronary artery disease: A cardiovascular magnetic resonance study

Objective: We sought to determine differences with cardiovascular magnetic resonance (CMR) in the morphology and composition of the carotid arteries between individuals with angiographically-defined obstructive coronary artery disease (CAD, = 50% stenosis, cases) and those with angiographically normal coronaries (no lumen irregularities, controls). Methods and results: 191 participants (50.3% female; 50.8% CAD cases) were imaged with a multi-sequence, carotid CMR protocol at 1.5T. For each segment of the carotid, lumen area, wall area, total vessel area (lumen area + wall area), mean wall thickness and the presence or absence of calcification and lipid-rich necrotic core were recorded bilaterally. In male CAD cases compared to male controls, the distal bulb had a significantly smaller lumen area (60.0 [plus or minus] 3.1 vs. 79.7 [plus or minus] 3.2 mm[super]2, p less than 0.001) and total vessel area (99.6 [plus or minus] 4.0 vs. 119.8 [plus or minus] 4.1 mm[super]2; p less than 0.001), and larger mean wall thickness (1.25 [plus or minus] 0.03 vs. 1.11 [plus or minus] 0.03 mm; p = 0.002). Similarly, the internal carotid had a smaller lumen area (37.5 [plus or minus] 1.8 vs. 44.6 [plus or minus] 1.8 mm[super]2; p = 0.006) and smaller total vessel area (64.0 [plus or minus] 2.3 vs. 70.9 [plus or minus] 2.4 mm[super]2; p = 0.04). These metrics were not significantly different between female groups in the distal bulb and internal carotid or for either gender in the common carotid. Male CAD cases had an increased prevalence of lipid-rich necrotic core (49.0% vs. 19.6%; p = 0.003), while calcification was more prevalent in both male (46.9% vs. 17.4%; p = 0.002) and female (33.3% vs. 14.6%; p = 0.031) CAD cases compared to controls. Conclusion: Males with obstructive CAD compared to male controls had carotid bulbs and internal carotid arteries with smaller total vessel and lumen areas, and an increased prevalence of lipid-rich necrotic core. Carotid calcification was related to CAD status in both males and females. Carotid CMR identifies distinct morphological and compositional differences in the carotid arteries between individuals with and without angiographically-defined obstructive CAD.Carotid Atherosclerosis (MRI) Progression Study (CAMPS, HL076378) and Cardiovascular Research Training Program (T-32, HL07838); and the General Clinical Research Center at the Wake Forest University School of Medicine (M01 RR-07122)

The epidemiology of coronary heart disease : A review

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/31999/1/0000041.pd

Phase Ill Investigations for the Banneker-Douglass Museum Expansion, The Courthouse Site (18AP63), 86-90 Franklin Street, , Annapolis, Maryland, 2001

Phase III archaeological excavations for the Banneker-Douglass Museum Expansion Project were conducted over a six-week period in July and August of 2001. Archaeology in Annapolis undertook the project at the request of the Maryland Commission on African American History and Culture and by the Maryland Department of Housing and Community Development. The open lot on the north side of the Museum is part of the larger Courthouse Site (18AP63), a multi component site in the historic district of Annapolis. Previous archaeology for the Banneker-Douglass Project determined this area to be eligible for inclusion in the National Register of Historic Places under Criterion D (archaeological significance). A new addition to the Banneker-Douglass Museum will impact all remaining cultural contexts. As no other alternatives are available, archaeology was planned to mitigate these losses. Known to have once held four separate dwellings built during the mid 19th century, the property was occupied until the structures were tom down in the 1970s. During the late 19th century, the area grew to become part of Annapolis' African-American community. Previous archaeology found intact cultural remains from this period including two different households' privies, a sheet midden, and other structural features. Current excavations pursued the retrieval and analyses of these contexts to increase the understanding of site formation processes and to provide additional information and insights into Annapolis' African-American community- its households, material culture, and adaptations. The development and everyday workings of African-American communities during the period of Jim Crow segregation have not been well documented. Examination of the built environment provides new insight into how and when this community developed. Ceramic, glass, and faunal analyses provide material comparable to other post Civil War African-American sites in Annapolis. This comparison allows the acknowledgment of the inevitable differences present within the African-American community-while also pursuing the nature of a common identity built around race and place