Cross-stream transport of asymmetric particles driven by oscillating shear

We study the dynamics of asymmetric, deformable particles in oscillatory, linear shear flow. By simulating the motion of a dumbbell, a ring polymer, and a capsule we show that cross-stream migration occurs for asymmetric elastic particles even in linear shear flow if the shear rate varies in time. The migration is generic as it does not depend on the particle dimension. Importantly, the migration velocity and migration direction are robust to variations of the initial particle orientation, making our proposed scheme suitable for sorting particles with asymmetric material properties.Comment: 5 pages, 4 figure

MRI-Based Risk Assessment for Incomplete Resection of Brain Metastases

Recent studies demonstrated that gross total resection of brain metastases cannot always be achieved. Subtotal resection (STR) can result in an early recurrence and might affect patient survival. We initiated a prospective observational study to establish a MRI-based risk assessment for incomplete resection of brain metastases.Peer Reviewe

Ahnlichkeitsanalyse biologisch aktiver Molekiile mit durch Autokorrelationsvektoren trainierten selbstorganisierenden Karten

Topological autocorrelation vectors can be used to estimate similarities of molecular structures. In the following paper we examinedifferent data sets of increasing size and complexity with this measure of similarity. All data sets contain substances with known biologicalactivity on the dopaminergic and benzodiazepine receptors. These two different classes of biological active substances can be separated by self-organizing maps, a kind of neural network well suited for clustering and visualization of similarity. The method is implemented on a massively parallel SIMD computer (MasPar MP-1) which is able to perform this analysis for databases of several thousand substances