645 research outputs found

    Cognitive Analytic Therapy in People with Learning Disability: An investigation into the common reciprocal roles found within this client group

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    Developments over the last twenty years have shown that, contrary to previous opinion, people with learning disabilities can benefit from psychotherapy (Sinason 1992; Kroese, Dagnan & Loumidia, 1997). Cognitive Analytic Therapy (CAT) has been adapted for use with a learning disability population (Ryle 2002). CAT collaboratively examines the Reciprocal Roles (RRs) a client plays in relationships. These are impacted by clients’ experiences of the world. The aim of this research is to identify which RRs may become apparent in working with people with learning disabilities. The therapy notes of participants (n=16) who had undergone CAT were examined and analysed using content analysis. Twenty-two different RRs were found. Four common Reciprocal Roles and two common idealised Reciprocal Roles were identified. Other observations about the data are presented. The limitations and clinical implications of the study are discussed

    The use of SIFT-MS in profiling the faecal volatile metabolome in horses with colic: a pilot study

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    SIFT-MS is used for the first time in profiling the volatile organic profile in faecal headspace in two groups of horses admitted to an equine hospital, one group with acute intestinal disease (colic) affecting the large colon, plus a control group of similarly managed horses admitted for non-gastrointestinal/metabolic reasons (e.g. acute orthopaedic injury). Compounds in faecal headspace which show statistically significant concentration differences between the groups are acetone and methanol. In addition, some ions at various m/z values show significantly different ion counts between the groups. Further information may be gleaned by using multivariate statistics in evaluating the differences between the two horse groups. Principal components analysis (PCA) and orthogonal partial least squares discriminant analysis (OPLS-DA) were evaluated for reducing the dimensionality of the SIFT-MS data, and OPLS-DA was found to be best at discriminating between the groups, particularly with SIFT-MS data acquired using the H3O+ precursor ion. Analysis of these data also show the significance of ammonia as a discriminating ion. These results show that SIFT-MS may potentially be used on the headspace of horse faecal samples for detecting altered microbial fermentation associated with acute intestinal disease of the colon

    Diabetes status and post-load plasma glucose concentration in relation to site-specific cancer mortality: findings from the original Whitehall study

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    ObjectiveWhile several studies have reported on the relation of diabetes status with pancreatic cancer risk, the predictive value of this disorder for other malignancies is unclear. Methods: The Whitehall study, a 25year follow-up for mortality experience of 18,006 men with data on post-challenge blood glucose and self-reported diabetes, allowed us to address these issues. Results: There were 2158 cancer deaths at follow-up. Of the 15 cancer outcomes, diabetes status was positively associated with mortality from carcinoma of the pancreas and liver, while the relationship with lung cancer was inverse, after controlling for a range of potential covariates and mediators which included obesity and socioeconomic position. After excluding deaths occurring in the first 10years of follow-up to examine the effect of reverse causality, the magnitude of the relationships for carcinoma of the pancreas and lung was little altered, while for liver cancer it was markedly attenuated. Conclusions: In the present study, diabetes status was related to pancreatic, liver, and lung cancer risk. Cohorts with serially collected data on blood glucose and covariates are required to further examine this area

    Recent topics of mesic atoms and mesic nuclei -- ϕ\phi mesic nuclei exist ?--

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    We study ϕ\phi-meson production in nuclei to investigate the in-medium modification of the ϕ\phi-meson spectral function at finite density. We consider (pˉ,ϕ{\bar p},\phi), (γ,p\gamma,p) and (π,n\pi^-,n) reactions to produce a ϕ\phi-meson inside the nucleus and evaluate the effects of the medium modifications to reaction cross sections. The structures of the bound states, ϕ\phi-mesic nuclei, are also studied. For strong absorptive interaction cases, we need to know the spectrum shape in a wide energy region to deduce the properties of ϕ\phi.Comment: Talk given at EXA08, Vienna, September 2008. To be published in the Proceedings, Hyperfine Interactions. 6 pages, 6 figure

    Pion-Lambda-Sigma Coupling Extracted from Hyperonic Atoms

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    The latest measurements of the atomic level width in Sigma-hyperonic Pb atom offer the most accurate datum in the region of low-energy Sigma-hyperon physics. Atomic widths are due to the conversion of Sigma-nucleon into Lambda-nucleon. In high angular momentum states this conversion is dominated by the one-pion exchange. A joint analysis of the data of the scattering of negative-Sigma on proton converting into a Lambda and a neutron and of the atomic widths allows to extract a pseudovector pion-hyperon-Sigma coupling constant of 0.048 with a statistical error of +-0.005 and a systematic one of +-0.004. This corresponds to a pseudoscalar coupling constant of 13.3 with a statistical uncertainty of 1.4 and a systematic one of 1.1.Comment: 12 pages, 1 figure, Use of Revtex.st

    Vacuum polarization radiative correction to the parity violating electron scattering on heavy nuclei

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    The effect of vacuum polarization on the parity violating asymmetry in the elastic electron-nucleus scattering is considered. Calculations are performed in the high-energy approximation with an exact account for the electric field of the nucleus. It is shown that the radiative correction to the parity violating asymmetry is logarithmically enhanced and the value of the correction is about -1%.Comment: 6 pages, 3 figures, REVTex

    Semiclassical Distorted Wave Model Analysis of the (π,K+)(\pi^-,K^+) Σ\Sigma Formation Inclusive Spectrum

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    (π,K+)(\pi^-,K^+) hyperon production inclusive spectra with pπ=1.2p_\pi =1.2 GeV/c measured at KEK on 12^{12}C and 28^{28}Si are analyzed by the semiclassical distorted wave model. Single-particle wave functions of the target nucleus are treated using Wigner transformation. This method is able to account for the energy and angular dependences of the elementary process in nuclear medium without introducing the factorization approximation frequently employed. Calculations of the (π+,K+)(\pi^+,K^+) Λ\Lambda formation process, for which there is no free parameter since the Λ\Lambda s.p. potential is known, demonstrate that the present model is useful to describe inclusive spectra. It is shown that in order to account for the experimental data of the Σ\Sigma^- formation spectra a repulsive Σ\Sigma-nucleus potential is necessary whose magnitude is not so strong as around 100 MeV previously suggested.Comment: 12 pages, 10 figures, accepted in Phys. Rev.

    Defining urban clusters to detect agglomeration economies

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    Agglomeration economies are a persistent subject of debate in regional science and city planning. Their definition turns on whether or not larger cities are more efficient than smaller ones. Here, we complement existing discussions on agglomeration economies by providing a sensitivity analysis of estimated externalities to the definitions of urban agglomeration. We regress wages versus population and jobs over thousands of different definitions of cities in France, based on an algorithmic aggregation of spatial units. We also search for evidence of larger inequalities in larger cities. This paper therefore focuses on the spatial and economic complexity of the mechanisms defining agglomeration within and between cities

    First measurement of kaonic helium-3 X-rays

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    The first observation of the kaonic 3He 3d - 2p transition was made using slow K- mesons stopped in a gaseous 3He target. The kaonic atom X-rays were detected with large-area silicon drift detectors using the timing information of the K+K- pairs of phi-meson decays produced by the DAFNE e+e- collider. The strong interaction shift of the kaonic 3He 2p state was determined to be -2+-2 (stat)+-4 (syst) eV.Comment: Accepted for publication in Phys. Lett.
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