Clinical and laboratory indicators in pregnant women with preeclampsia

The objective of this study is to compare clinical and laboratory indicators in pregnant women with preeclampsia (PE) compared with women with physiological pregnancy. The study group included 209 women with physiological pregnancy and 250 pregnant women with PE. We studied coagulogram data, biochemical blood analysis, and the level of systolic and diastolic blood pressure before and during pregnanc

Genetic determinants of complicated pregnancy

The connections of polymorphic variants of the gene of vasoactive hormones with the level of arterial pressure in pregnant women, depending on the development of preeclampsia (PE), have been studie

The study of the role of maternal and fetal risk factors in the development of placental insufficiency

The objectives were to study the role of maternal and fetal risk factors in the development of placental insufficiency (PI) and fetal growth retardation syndrome (FGRS

Approaches to the construction of simulation model of the process optimization of rare plants microclonal propagation

The authors present approaches to constructing an imitation model for the optimization of the process of rare plants microclonal reproduction (on the example of the Belgorod region), which allow to identify the most effective ways of explants sterilization, to define the optimal composition of nutrient media for regenerants growth (tube plants) and growth regulators (phytohormones) for propagation of mini-plant

Polymorphisms of genes and the risk of preeclampsia

They studied the relations of genetic polymorphisms with the risk of preeclampsia occurrence depending on hereditary complicatio

Genetic determinants of endometriosis and uterine myoma combinatin

The objective of the research was a bioinformatic study of the involvement of candidate genes in the formation of a combination of endometriosis with uterine myoma in wome

Low homology between 2019-nCoV Orf8 protein and its SARS-CoV counterparts questions their identical function

SARS-CoV accessory protein Orf8b is involved in suppressing interferon-mediated immune response of the infected cell and this might lead to supposition that the corresponding protein 2019-nCoV Orf8 shares the same role. But the tertiary structures of these proteins are still unknown, and the primary structures demonstrate very low homology and different calculating parameters. This time they both are affected by stabilizing selection and in natural viral populations do not tend to be deleted. The question whether in this case very different proteins could share the same function rises from the present dat

The effectiveness of glucocorticoid therapy in patients with chronic glomerulonephritis, depending on the polymorphic markers of cytokine genes

The paper presents the results of a study of interrelationships of polymorphic cytokine loci (rs1800629 TNFα, rs909253 Ltα, rs767455 TNFR1 and rs1800469 TGFβ-1) with the features of glucocorticoid therapy in patients with chronic glomerulonephriti

The Role of the Gene-Gene and Gene-Environment Interactions of Polymorphic Loci of Matrix Metalloproteinases in Forming the Risk of Ischemic Stroke on the Background of Arterial Hypertension in Men

To analyze the role of genetic polymorphisms of matrix metalloproteinase (MMP) genes and their gene-gene and gene-environment interactions in the formation of ischemic stroke (IS) in men with arterial hypertension (AH

Candidate genes and clinical-laboratory indices in pregnant women depending on the development of preeclampsia

The relationship between polymorphic variants of folate metabolism genes with clinical (blood pressure level before and at the end of pregnancy) and clinical and laboratory indicators (proteinuria, fibrinogen, total protein, urea and creatinine in the blood, activated partial thromboplastin time, thrombin time) were studied in pregnant women with preeclampsi