Análisis del tráfico de red en la ETSINF: Estudio del potencial para el ahorro energético

[ES] El progresivo crecimiento del tráfico que circula por la red y la incorporación de dispositivos de mayor potencia implican un consumo energético elevado, de gran impacto económico y ambiental. Por ello, el uso eficiente de las redes de comunicación y la reducción del consumo energético son temas clave en los últimos años. En este trabajo se ha analizado el tráfico de red en la ETSINF con el objetivo de definir el patrón de comunicación de cada puerto del switch principal, caracterizar los periodos de inactividad y estimar, en forma de porcentaje, el potencial para el ahorro energético. Se han elaborado códigos que sistematizan la captura de datos del tráfico, dibujan las gráficas volumen de datos/tiempo, definen y representan mediante histogramas los periodos de inactividad, calculan el porcentaje de actividad de los puertos y determinan la energía consumida por cada puerto. Finalmente se ha estimado el margen para ahorro de energía de cada puerto y el global del switch a lo largo del periodo de estudio, llegando a la conclusión de que el potencial de ahorro es significativo, por lo que debería valorarse hacer un estudio más amplio extensivo a todos los switches secundarios y a lo largo de todo un año.[EN] The progressive growth of the Internet traffic and the incorporation of higher power devices involve high energy consumption, of great economic and environmental impact. Therefore, the efficient use of communication networks and the reduction of energy consumption are key issues in recent years. In this work, the network traffic in the ETSINF is analyzed in order to define the communication pattern of each port of the main switch, to characterize idle periods and to estimate, as a percentage, the potential for energy saving. Codes have been developed that systematize the traffic data capture, graph the data volume/time, define and represent by means of histograms the idle periods, calculate the percentage of activity of each port and determine the energy consumed by each port. Finally, the energy saving margin of each port and the global of the switch have been estimated throughout the period of study, concluding that the energy saving potential is significant. For this reason, it should be considered to perform a study extended to all the secondary switches and throughout a whole year.Pedrón Basset, D. (2017). Análisis del tráfico de red en la ETSINF: Estudio del potencial para el ahorro energético. http://hdl.handle.net/10251/88836.TFG

Análisis del comportamiento del fenómeno Backdraft en recintos confinados

[ES] El Backdraft consiste en la reavivación de un incendio confinado, el cual estaba falto de  comburente y se le aporta una fuente suficiente para alcanzar el límite superior de  inflamabilidad, provocando una bola de fuego consecuencia de una deflagración en el interior  del recinto. Esta situación puede generar graves accidentes en incendios que aparentemente  estaban apagados. En ese contexto, en este trabajo se pretende mediante el uso de las nuevas  tecnologías de diseño y simulación, analizar este fenómeno de combustión en recintos  confinados denominado Backdraft, para estudiar su comportamiento, su potencia y su  peligrosidad, con la finalidad de encontrar medidas preventivas tanto de detección como de  extinción. [CA] El Backdraft consisteix en la reanimació de un incendi confinat, el qual estava mancat de  comburent i se li aporta una font suficient com per arribar el límit superior de inflamabilitat,  provocant una bola de foc a conseqüència de una deflagració en el interior del recinte.  Aquesta situació pot generar accidents graus als incendis que aparentment estaven apagats.  En aquest context, en aquest treball es pretén mitjançant l’ús de les noves tecnologies de  disseny i simulació, analitzar aquest fenomen de combustió en recintes confinats denominat  Backdraft, per a estudiar el seu comportament, la seua potencia i perillositat, amb la finalitat  de trobar mides preventives tant de detecció com de extinció. [EN] Backdraft phenomena consist on the revival of a confined fire, which was devoid of oxidizer  and a source of fresh air is provided, reaching the upper limit of flammability, causing a fireball  resulting from a deflagration inside the enclosure. This situation can lead to serious fire  accidents that would were apparently extinguished. In this context, the aim of this work is to  analyze that combustion phenomena in confined spaces called Backdraft, through the use of  new design and simulation technologies to study its behavior, its potential and its  dangerousness, in order to find preventive measures both detection and extinction. Basset Tomás, D. (2017). Análisis del comportamiento del fenómeno Backdraft en recintos confinados. http://hdl.handle.net/10251/78517.TFG

Connecting Clump Sizes in Turbulent Disk Galaxies to Instability Theory

In this letter we study the mean sizes of Halpha clumps in turbulent disk galaxies relative to kinematics, gas fractions, and Toomre Q. We use 100~pc resolution HST images, IFU kinematics, and gas fractions of a sample of rare, nearby turbulent disks with properties closely matched to z~1.5-2 main-sequence galaxies (the DYNAMO sample). We find linear correlations of normalized mean clump sizes with both the gas fraction and the velocity dispersion-to-rotation velocity ratio of the host galaxy. We show that these correlations are consistent with predictions derived from a model of instabilities in a self-gravitating disk (the so-called "violent disk instability model"). We also observe, using a two-fluid model for Q, a correlation between the size of clumps and self-gravity driven unstable regions. These results are most consistent with the hypothesis that massive star forming clumps in turbulent disks are the result of instabilities in self-gravitating gas-rich disks, and therefore provide a direct connection between resolved clump sizes and this in situ mechanism.Comment: Accepted to Apj Letter

Differential expression of the RTP/Drg1/Ndr1 gene product in proliferating and growth arrested cells

AbstractUsing a differential display method to identify differentiation-related genes in human myelomonocytic U937 cells, we cloned the cDNA of a gene identical to Drg1 and homologous to other recently discovered genes, respectively human RTP and Cap43 and mouse Ndr1 and TDD5 genes. Their open reading frames encode proteins highly conserved between mouse and man but which do not share homology with other know proteins. Conditions in which mRNAs are up-regulated suggest a role for the protein in cell growth arrest and terminal differentiation. We raised antibodies against a synthetic peptide reproducing a characteristic sequence of the putative polypeptide chain. These antibodies revealed a protein with the expected 43 kDa molecular mass, up-regulated by phorbol ester, retinoids and 1,25-(OH)2 vitamin D3 in U937 cells. It was increased in mammary carcinoma MCF-7 cells treated by retinoids and by the anti-estrogen ICI 182,780 but not by 4-hydroxytamoxifen. The mouse Drg1 homologous protein was up-regulated by retinoic acid in C2 myogenic cells. The diversity of situations in which expression of RTP/Drg1/Ndr1 has now been observed shows that it is widely distributed and up-regulated by various agents. Here we show that ligands of nuclear transcription factors involved in cell differentiation are among the inducers of this novel protein

High tempo music prolongs high intensity exercise

Music has been shown to reduce rating of perceived exertion, increase exercise enjoyment and enhance exercise performance, mainly in low-moderate intensity exercises. However, the effects of music are less conclusive with high-intensity activities. The purpose of this with-participant design study was to compare the effects of high tempo music (130 bpm) to a no-music condition during repeated high intensity cycling bouts (80% of peak power output (PPO)) on the following measures: time to exercise end-point, rating of perceived exertion (RPE), heart rate (HR), breathing frequency, ventilatory kinetics and blood lactate (BL). Under the music condition, participants exercised 10.7% longer (p = 0.035; Effect size (ES) = 0.28) (increase of 1 min) and had higher HR (4%; p = 0.043; ES = 0.25), breathing frequency (11.6%; p < 0.001; ES = 0.57), and RER (7% at TTF; p = 0.021; ES = 1.1) during exercise, as measured at the exercise end-point. Trivial differences were observed between conditions in RPE and other ventilatory kinetics during exercise. Interestingly, 5 min post-exercise termination, HR recovery was 13.0% faster following the music condition (p < 0.05) despite that music was not played during this period. These results strengthen the notion that music can alter the association between central motor drive, central cardiovascular command and perceived exertion, and contribute to prolonged exercise durations at higher intensities along with a quicken HR recovery

Comparison of rainforest butterfly assemblages across three biogeographical regions using standardized protocols

Insects, like most other organisms, are more diverse in tropical than in temperate regions, but standardized comparisons of diversity among tropical regions are rare. Disentangling the effects of ecological, evolutionary, and biogeographic factors on community diversity requires standardized protocols and long-term studies. We compared the abundance and diversity of butterflies using standardised ‘Pollard walk’ transect counts in the understory of closed-canopy lowland rainforests in Panama (Barro Colorado Island, BCI), Thailand (Khao Chong, KHC) and Papua New Guinea (Wanang, WAN). We observed 1792, 1797 and 3331 butterflies representing 128, 131 and 134 species during 230, 231 and 120 transects at BCI, KHC and WAN, respectively. When corrected for length and duration of transects, butterfly abundance and species richness were highest at WAN and KHC, respectively. Although high butterfly abundance at WAN did not appear to result from methodological artefacts, the biological meaning of this observation remains obscure. The WAN site appeared as floristically diverse as KHC, but supported lower butterfly diversity. This emphasizes that factors other than plant diversity, such as biogeographic history, may be crucial for explaining butterfly diversity. The KHC butterfly fauna may be unusually species rich because the site is at a biogeographic crossroads between the Indochinese and Sundaland regions. In contrast, WAN is firmly within the Australian biogeographic region and relatively low species numbers may result from island biogeographic processes. The common species at each of the three sites shared several traits: fruit and nectar feeders were equally represented, more than half of common species fed on either epiphytes or lianas as larvae, and their range in wing sizes was similar. These observations suggest that Pollard walks in different tropical rainforests target similar assemblages of common species, and, hence, represent a useful tool for long-term monitoring of rainforest butterfly assemblages.Organismic and Evolutionary Biolog

A novel algorithmic approach to generate consensus treatment guidelines in adult Acute Myeloid Leukaemia

Induction therapy for acute myeloid leukaemia (AML) has changed with the approval of a number of new agents. Clinical guidelines can struggle to keep pace with an evolving treatment and evidence landscape and therefore identifying the most appropriate front-line treatment is challenging for clinicians. Here, we combined drug eligibility criteria and genetic risk stratification into a digital format, allowing the full range of possible treatment eligibility scenarios to be defined. Using exemplar cases representing each of the 22 identified scenarios, we sought to generate consensus on treatment choice from a panel of nine aUK AML experts. We then analysed >2500 real-world cases using the same algorithm, confirming the existence of 21/22 of these scenarios and demonstrating that our novel approach could generate a consensus AML induction treatment in 98% of cases. Our approach, driven by the use of decision trees, is an efficient way to develop consensus guidance rapidly and could be applied to other disease areas. It has the potential to be updated frequently to capture changes in eligibility criteria, novel therapies and emerging trial data. An interactive digital version of the consensus guideline is available

Dynamically Controlling Image Integration Onboard the Star-Planet Activity Research CubeSat (SPARCS)

The Star-Planet Activity Research CubeSat (SPARCS) is a 6U CubeSat astronomical observatory underdevelopment and will be entirely dedicated to the photometric monitoring of the flaring activity of M dwarfs at near-UV (258 nm – 308 nm) and far-UV (153 nm–171 nm) wavelengths. The SPARCS science pay load is composed of a 9-cm telescope that projects a 40’ field-of-view onto two UV-optimized delta-doped charge-coupled devices (CCDs), which are controlled by a dedicated payload processor board. Given that M dwarf flares in the UV are expected to be capable of reaching amplitudes ∼14,000 times above their quiescent flux, with durations that can be as short as a couple of minutes, the SPARCS payload processor is designed to be able to dynamically adjust the imaging system’s integration times and gains on the fly to reduce CCD pixel saturation issues when flaring events are detected. The SPARCS payload processor is a BeagleBone Black (BBB) with a protective Pumpkin Motherboard Module 2, and runs a custom fully Python-based software to perform active detector thermal control, manage science observations, and apply near-real time image processing to autonomously adjust the exposure times and gains of the detectors upon flare detection. Here we present the approach adopted for that automated dynamic exposure control, as well as its pre-flight tests and performance using simulated M dwarf light curves and full-frame images in the two SPARCS passbands