The Relationship between Cytokines and Toxoplasma Infection in Heart Disease Patients

Toxoplasmosis is the general term for infection and disease in man and animal caused by a parasite called Toxoplasma gondii, this disease is prevalent among different categories of people, Heart disease are one of them. Because of the dormancy status of T. gondii, there is ambiguity and variation in the immunity of patients. This study aimed to investigate the immune status of heart disease patients infected with toxoplasmosis. Two hundred and fifty samples of both heart disease patients and controls had been tested by ELISA technique to detect anti-Toxoplasma Abs (IgG and IgM). The positive samples with toxoplasmosis were tested to detect the level of interleukins (IL-10, IL-12 and IL-17).       The result of this study revealed the prevalence of toxoplasmosis among heart disease patient in about (43.33% IgG and 0.66% IgM). The results of interleukins appeared high level of IL-12 (82.85 pg./ml) in heart disease patients infected with toxoplasmosis when compared with control (60.97 pg./ml) with significant difference between them at p?0.05, while there was no significant difference in IL-10 between patients and controls. The results also showed decreased level of IL-17 in patients with heart disease. The increased level of IL-12 in patient with heart disease infected with toxoplasmosis indicate to the activity of cell mediated immunity in those patients and may be lead to provoke an inflammatory status in the heart valves and muscle then worse heart disease to be sever and need complicated treatment

The Relationship between Cytokines and Toxoplasma Infection in Heart Disease Patients

Toxoplasmosis is the general term for infection and disease in man and animal caused by a parasite called Toxoplasma gondii, this disease is prevalent among different categories of people, Heart disease are one of them. Because of the dormancy status of T. gondii, there is ambiguity and variation in the immunity of patients. This study aimed to investigate the immune status of heart disease patients infected with toxoplasmosis. Two hundred and fifty samples of both heart disease patients and controls had been tested by ELISA technique to detect anti-Toxoplasma Abs (IgG and IgM). The positive samples with toxoplasmosis were tested to detect the level of interleukins (IL-10, IL-12 and IL-17).       The result of this study revealed the prevalence of toxoplasmosis among heart disease patient in about (43.33% IgG and 0.66% IgM). The results of interleukins appeared high level of IL-12 (82.85 pg./ml) in heart disease patients infected with toxoplasmosis when compared with control (60.97 pg./ml) with significant difference between them at p≤0.05, while there was no significant difference in IL-10 between patients and controls. The results also showed decreased level of IL-17 in patients with heart disease. The increased level of IL-12 in patient with heart disease infected with toxoplasmosis indicate to the activity of cell mediated immunity in those patients and may be lead to provoke an inflammatory status in the heart valves and muscle then worse heart disease to be sever and need complicated treatment

Investigation of infection of intestinal parasites Entamoeba histolytica and Giardia lamblia among patients which attending of the Health Centers of Gharraf City / Thi- Qar province

The intestinal parasites of Entamoeba hstolytica and Giardia lamblia are among the major causes of diarrhea throughout the world.The current study was conducted from October 2015 to February 2016 to investigate the spread of intestinal parasites Entamoeba histolytica and Giardia lamblia for patients who have been referred to the Gharraf Model Center and the Main Graff center , which suffer from intestinal disorders. The study included 488 stool samples for patients of different ages and both sexes (males and females). The number of samples required for examination was 228 and 46.72% compared with 260 negative samples for examination and 53.27%. The positive results were 202 for  Entamoeba histolytica parasites by 5, 88% compared with 20 and 8.7% of the Giardia lamblia parasite and 2.6 % for Entamoeba hstolytica and Giardia lamblia.The study showed no significant differences between males and females. The highest rates of parasitic infection in the largest of the 15-year age group, which reached 49.12%. The highest incidence of the city population was 65.75% compared with the Rusticate population 34.21%. 

Investigation of infection of intestinal parasites Entamoeba histolytica and Giardia lamblia among patients which attending of the Health Centers of Gharraf City / Thi- Qar province

The intestinal parasites of Entamoeba hstolytica and Giardia lamblia are among the major causes of diarrhea throughout the world.The current study was conducted from October 2015 to February 2016 to investigate the spread of intestinal parasites Entamoeba histolytica and Giardia lamblia for patients who have been referred to the Gharraf Model Center and the Main Graff center , which suffer from intestinal disorders. The study included 488 stool samples for patients of different ages and both sexes (males and females). The number of samples required for examination was 228 and 46.72% compared with 260 negative samples for examination and 53.27%. The positive results were 202 for  Entamoeba histolytica parasites by 5, 88% compared with 20 and 8.7% of the Giardia lamblia parasite and 2.6 % for Entamoeba hstolytica and Giardia lamblia.The study showed no significant differences between males and females. The highest rates of parasitic infection in the largest of the 15-year age group, which reached 49.12%. The highest incidence of the city population was 65.75% compared with the Rusticate population 34.21%.