Integration and Reintegration: Comparing pathways to citizenship through asylum and criminal justice

The development of scholarship related to particular categories of people who are subject to different forms of social control often results in subfields that become or remain isolated from each other. As an example, theory and research relating to the reintegration of ex-offenders and the integration of asylum seekers have developed almost completely independently. However, both processes involve people who are marginalized and stigmatized through legal and social processes, and policies and practices in the two fields share somewhat similar concepts and goals. This article therefore seeks to identify insights through a critical comparison of these two areas of research, theory and practice, with the intention of enriching our understanding of both. This comparison highlights that the frameworks reviewed here enable us to move beyond a narrow focus on service user’s behaviours, needs or risks, and into an examination of questions of identity, belonging and justice

Precancerous Stem Cells Have the Potential for both Benign and Malignant Differentiation

Cancer stem cells (CSCs) have been identified in hematopoietic and solid tumors. However, their precursors—namely, precancerous stem cells (pCSCs) —have not been characterized. Here we experimentally define the pCSCs that have the potential for both benign and malignant differentiation, depending on environmental cues. While clonal pCSCs can develop into various types of tissue cells in immunocompetent mice without developing into cancer, they often develop, however, into leukemic or solid cancers composed of various types of cancer cells in immunodeficient mice. The progress of the pCSCs to cancers is associated with the up-regulation of c-kit and Sca-1, as well as with lineage markers. Mechanistically, the pCSCs are regulated by the PIWI/AGO family gene called piwil2. Our results provide clear evidence that a single clone of pCSCs has the potential for both benign and malignant differentiation, depending on the environmental cues. We anticipate pCSCs to be a novel target for the early detection, prevention, and therapy of cancers

Smooth Parametric Surfaces and n-Sided Patches

CAGD is reviewed. In particular, we are concerned with how parametric surface patches for CAGD can be pieced together to form a smooth Ck surface. The theory is applied to the problem of filling an n-sided hole occurring within a smooth rectangular patch complex. A number of solutions to this problem are surveyed. 1

Inflation persistence during periods of structural change: an assessment using Greek data

CPI inflation, Persistence, Structural change, E31, E37,