946 research outputs found
Device independent quantum key distribution secure against coherent attacks with memoryless measurement devices
Device independent quantum key distribution aims to provide a higher degree
of security than traditional QKD schemes by reducing the number of assumptions
that need to be made about the physical devices used. The previous proof of
security by Pironio et al. applies only to collective attacks where the state
is identical and independent and the measurement devices operate identically
for each trial in the protocol. We extend this result to a more general class
of attacks where the state is arbitrary and the measurement devices have no
memory. We accomplish this by a reduction of arbitrary adversary strategies to
qubit strategies and a proof of security for qubit strategies based on the
previous proof by Pironio et al. and techniques adapted from Renner.Comment: 13 pages. Expanded main proofs with more detail, miscellaneous edits
for clarit
Six new species of Utricularia (Lentibulariaceae) from Northern Australia
Six new species of Utricularia (Lentibulariaceae) are recognised from northern Australia. Descriptions of the new species Utricularia albertiana R.W.Jobson & Baleeiro, U. bidentata R.W.Jobson & Baleeiro, U. hamata R.W.Jobson & M.D.Barrett, U. magna R.W.Jobson & M.D.Barrett, U. papilliscapa R.W.Jobson & M.D.Barrett, and U. limmenensis R.W.Jobson (Lentibulariaceae) are provided. Diagnostic features for all six species are illustrated, and distribution, habitat, and conservation status are discussed
The Role of Spokesperson in Ambiguous and Complex Crises: The CDC and Anthrax
This study evaluates the role of spokespersons in complex organizations facing ambiguous crises. Specifically, the Centers for Disease Control and Prevention’s (CDC) response to the anthrax crisis in 2001 is offered as a case study. A content analysis of the print media coverage of the anthrax crisis reveals that many claiming affiliation with the CDC spoke on behalf of the organization, resulting in what appeared to be a fragmented CDC message. The study concludes that the CDC’s failure to provide a central spokesperson contributed to the ambiguity of the situation
Motion analysis of match-play in elite U12 to U16 age-group soccer players
The aim of this study was to quantify the motion demands of match-play in elite U12 to U16 age-group soccer players. Altogether, 112 players from two professional soccer clubs at five age-group levels (U12–U16) were monitored during competitive matches (n=14) using a 5 Hz non-differential global positioning system (NdGPS). Velocity thresholds were normalized for each age-group using the mean squad times for a flying 10 m sprint test as a reference point. Match performance was reported as total distance, high-intensity distance, very high-intensity distance, and sprint distance. Data were reported both in absolute (m) and relative (m min-1) terms due to a rolling substitute policy. The U15 (1.35±0.09 s) and U16 (1.31±0.06 s) players were significantly quicker than the U12 (1.58±0.10 s), U13 (1.52±0.07 s), and U14 (1.51±0.08 s) players in the flying 10 m sprint test (P U12, U13, U14), high-intensity distance (U16 > U12, U13, U14, U15), very high-intensity distance (U16 4 U12, U13), and sprint distance (U16 > U12, U13) than their younger counterparts (P<0.05). When the data are considered relative to match exposure, few differences are apparent. Training prescription for youth soccer players should consider the specific demands of competitive match-play in each age-group
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Repurposing Albendazole: new potential as a chemotherapeutic agent with preferential activity against HPV-negative head and neck squamous cell cancer.
Albendazole is an anti-helminthic drug that has been shown to exhibit anti-cancer properties, however its activity in head and neck squamous cell cancer (HNSCC) was unknown. Using a series of in vitro assays, we assessed the ability of albendazole to inhibit proliferation in 20 HNSCC cell lines across a range of albendazole doses (1 nM-10 ÎĽM). Cell lines that responded to treatment were further examined for cell death, inhibition of migration and cell cycle arrest. Thirteen of fourteen human papillomavirus-negative HNSCC cell lines responded to albendazole, with an average IC50 of 152 nM. In contrast, only 3 of 6 human papillomavirus-positive HNSCC cell lines responded. Albendazole treatment resulted in apoptosis, inhibition of cell migration, cell cycle arrest in the G2/M phase and altered tubulin distribution. Normal control cells were not measurably affected by any dose tested. This study indicates that albendazole acts to inhibit the proliferation of human papillomavirus-negative HNSCC cell lines and thus warrants further study as a potential chemotherapeutic agent for patients suffering from head and neck cancer
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Poverty, Disease, and the Ecology of Complex Systems
Understanding why some human populations remain persistently poor remains a significant challenge for both the social and natural sciences. The extremely poor are generally reliant on their immediate natural resource base for subsistence and suffer high rates of mortality due to parasitic and infectious diseases. Economists have developed a range of models to explain persistent poverty, often characterized as poverty traps, but these rarely account for complex biophysical processes. In this Essay, we argue that by coupling insights from ecology and economics, we can begin to model and understand the complex dynamics that underlie the generation and maintenance of poverty traps, which can then be used to inform analyses and possible intervention policies. To illustrate the utility of this approach, we present a simple coupled model of infectious diseases and economic growth, where poverty traps emerge from nonlinear relationships determined by the number of pathogens in the system. These nonlinearities are comparable to those often incorporated into poverty trap models in the economics literature, but, importantly, here the mechanism is anchored in core ecological principles. Coupled models of this sort could be usefully developed in many economically important biophysical systems—such as agriculture, fisheries, nutrition, and land use change—to serve as foundations for deeper explorations of how fundamental ecological processes influence structural poverty and economic development
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