Investigating the mass of the intermediate mass black hole candidate HLX-1 with the SLIMBH model

In this paper we present a comprehensive study of the mass of the intermediate mass black hole candidate HLX-1 in the galaxy ESO 243-49. We analyse the continuum X-ray spectra collected by Swift, XMM-Newton, and Chandra with the slim disc model, SLIMBH, and estimate the black hole mass for the full range of inclination (inc = 0{\deg} - 85{\deg}) and spin (a* = 0 - 0.998). The relativistic SLIMBH model is particularly suited to study high luminosity disc spectra as it incorporates the effects of advection, such as the shift of the inner disc edge towards smaller radii and the increasing height of the disc photosphere (including relativistic ray-tracing from its proper location rather than the mid-plane of the disc). We find for increasing values of inclination that a zero spin black hole has a mass range of 6,300 - 50,900 M_sun and a maximally spinning black hole has a mass between 16,900 - 191,700 M_sun. This is consistent with previous estimates and reinforces the idea that HLX-1 contains an intermediate mass black hole.Comment: updated version, published in Astronomy and Astrophysic

The Cool Accretion Disk in ESO 243-49 HLX-1: Further Evidence of an Intermediate Mass Black Hole

With an inferred bolometric luminosity exceeding 10^42 erg/s, HLX-1 in ESO 243-49 is the most luminous of ultraluminous X-ray sources and provides one of the strongest cases for the existence of intermediate mass black holes. We obtain good fits to disk-dominated observations of the source with BHSPEC, a fully relativistic black hole accretion disk spectral model. Due to degeneracies in the model arising from the lack of independent constraints on inclination and black hole spin, there is a factor of 100 uncertainty in the best-fit black hole mass M. Nevertheless, spectral fitting of XMM-Newton observations provides robust lower and upper limits with 3000 Msun < M < 3 x 10^5 Msun, at 90% confidence, placing HLX-1 firmly in the intermediate-mass regime. The lower bound on M is entirely determined by matching the shape and peak energy of the thermal component in the spectrum. This bound is consistent with (but independent of) arguments based solely on the Eddington limit. Joint spectral modelling of the XMM-Newton data with more luminous Swift and Chandra observations increases the lower bound to 6000 Msun, but this tighter constraint is not independent of the Eddington limit. The upper bound on M is sensitive to the maximum allowed inclination i, and is reduced to M < 10^5 Msun if we limit i < 75 deg.Comment: 10 pages, 7 figures, accepted for publication in Ap

X-ray Variability and Hardness of ESO 243-49 HLX-1: Clear Evidence for Spectral State Transitions

The ultra-luminous X-ray (ULX) source ESO 243-49 HLX-1 currently provides the strongest evidence for the existence of intermediate mass black holes. We conduct an ongoing monitoring campaign with the Swift X-ray Telescope and found that HLX-1 showed two fast rise and exponential decay with increases in the count rate of a factor ~40 separated by 375+/-13 days. We obtained new XMM-Newton and Chandra dedicated pointings that were triggered at the lowest and highest luminosities, respectively. The unabsorbed luminosities ranged from 1.9x10^40 to 1.25x10^42 erg/s. We confirm here the detection of spectral state transitions from HLX-1 reminiscent of Galactic black hole binaries: at high luminosities, the X-ray spectrum showed a thermal state dominated by a disk component with temperatures of 0.26 keV at most, and at low luminosities the spectrum is dominated by a hard power law with a photon index in the range 1.4-2.1, consistent with a hard state. The source was also observed in a steep power law state. In the thermal state, the luminosity of the disk component appears to scale with the fourth power of the inner disk temperature which supports the presence of an optically thick, geometrically thin accretion disk. The low fractional variability (rms of 9+/-9%) in this state also suggests the presence of a dominant disk. The spectral changes and long-term variability of the source cannot be explained by variations of the beaming angle and are not consistent with the source being in a super-Eddington accretion state. HLX-1 is thus an unusual ULX as it is similar to Galactic black hole binaries, which have non-beamed and sub-Eddington emission, but with luminosities 3 orders of magnitude higher. In this picture, a lower limit on the mass of the black hole of >9000 M_sun can be derived, and the disk temperature in the thermal state also suggests the presence of a black hole of a few 10^3 M_sun.Comment: accepted for publication in ApJ (October 10, 2011, v740-1); 11 figures, 13 pages with emulateapj styl

Genomic Hotspots for Adaptation: The Population Genetics of Müllerian Mimicry in the Heliconius melpomene Clade

Wing patterning in Heliconius butterflies is a longstanding example of both Müllerian mimicry and phenotypic radiation under strong natural selection. The loci controlling such patterns are “hotspots” for adaptive evolution with great allelic diversity across different species in the genus. We characterise nucleotide variation, genotype-by-phenotype associations, linkage disequilibrium, and candidate gene expression at two loci and across multiple hybrid zones in Heliconius melpomene and relatives. Alleles at HmB control the presence or absence of the red forewing band, while alleles at HmYb control the yellow hindwing bar. Across HmYb two regions, separated by ∼100 kb, show significant genotype-by-phenotype associations that are replicated across independent hybrid zones. In contrast, at HmB a single peak of association indicates the likely position of functional sites at three genes, encoding a kinesin, a G-protein coupled receptor, and an mRNA splicing factor. At both HmYb and HmB there is evidence for enhanced linkage disequilibrium (LD) between associated sites separated by up to 14 kb, suggesting that multiple sites are under selection. However, there was no evidence for reduced variation or deviations from neutrality that might indicate a recent selective sweep, consistent with these alleles being relatively old. Of the three genes showing an association with the HmB locus, the kinesin shows differences in wing disc expression between races that are replicated in the co-mimic, Heliconius erato, providing striking evidence for parallel changes in gene expression between Müllerian co-mimics. Wing patterning loci in Heliconius melpomene therefore show a haplotype structure maintained by selection, but no evidence for a recent selective sweep. The complex genetic pattern contrasts with the simple genetic basis of many adaptive traits studied previously, but may provide a better model for most adaptation in natural populations that has arisen over millions rather than tens of years

The Athena X-ray Integral Field Unit: a consolidated design for the system requirement review of the preliminary definition phase

The Athena X-ray Integral Unit (X-IFU) is the high resolution X-ray spectrometer, studied since 2015 for flying in the mid-30s on the Athena space X-ray Observatory, a versatile observatory designed to address the Hot and Energetic Universe science theme, selected in November 2013 by the Survey Science Committee. Based on a large format array of Transition Edge Sensors (TES), it aims to provide spatially resolved X-ray spectroscopy, with a spectral resolution of 2.5 eV (up to 7 keV) over an hexagonal field of view of 5 arc minutes (equivalent diameter). The X-IFU entered its System Requirement Review (SRR) in June 2022, at about the same time when ESA called for an overall X-IFU redesign (including the X-IFU cryostat and the cooling chain), due to an unanticipated cost overrun of Athena. In this paper, after illustrating the breakthrough capabilities of the X-IFU, we describe the instrument as presented at its SRR, browsing through all the subsystems and associated requirements. We then show the instrument budgets, with a particular emphasis on the anticipated budgets of some of its key performance parameters. Finally we briefly discuss on the ongoing key technology demonstration activities, the calibration and the activities foreseen in the X-IFU Instrument Science Center, and touch on communication and outreach activities, the consortium organisation, and finally on the life cycle assessment of X-IFU aiming at minimising the environmental footprint, associated with the development of the instrument. Thanks to the studies conducted so far on X-IFU, it is expected that along the design-to-cost exercise requested by ESA, the X-IFU will maintain flagship capabilities in spatially resolved high resolution X-ray spectroscopy, enabling most of the original X-IFU related scientific objectives of the Athena mission to be retained. (abridged).Comment: 48 pages, 29 figures, Accepted for publication in Experimental Astronomy with minor editin

The Athena X-ray Integral Field Unit: a consolidated design for the system requirement review of the preliminary definition phase

The Athena X-ray Integral Unit (X-IFU) is the high resolution X-ray spectrometer studied since 2015 for flying in the mid-30s on the Athena space X-ray Observatory. Athena is a versatile observatory designed to address the Hot and Energetic Universe science theme, as selected in November 2013 by the Survey Science Committee. Based on a large format array of Transition Edge Sensors (TES), X-IFU aims to provide spatially resolved X-ray spectroscopy, with a spectral resolution of 2.5 eV (up to 7 keV) over a hexagonal field of view of 5 arc minutes (equivalent diameter). The X-IFU entered its System Requirement Review (SRR) in June 2022, at about the same time when ESA called for an overall X-IFU redesign (including the X-IFU cryostat and the cooling chain), due to an unanticipated cost overrun of Athena. In this paper, after illustrating the breakthrough capabilities of the X-IFU, we describe the instrument as presented at its SRR (i.e. in the course of its preliminary definition phase, so-called B1), browsing through all the subsystems and associated requirements. We then show the instrument budgets, with a particular emphasis on the anticipated budgets of some of its key performance parameters, such as the instrument efficiency, spectral resolution, energy scale knowledge, count rate capability, non X-ray background and target of opportunity efficiency. Finally, we briefly discuss the ongoing key technology demonstration activities, the calibration and the activities foreseen in the X-IFU Instrument Science Center, touch on communication and outreach activities, the consortium organisation and the life cycle assessment of X-IFU aiming at minimising the environmental footprint, associated with the development of the instrument. Thanks to the studies conducted so far on X-IFU, it is expected that along the design-to-cost exercise requested by ESA, the X-IFU will maintain flagship capabilities in spatially resolved high resolution X-ray spectroscopy, enabling most of the original X-IFU related scientific objectives of the Athena mission to be retained. The X-IFU will be provided by an international consortium led by France, The Netherlands and Italy, with ESA member state contributions from Belgium, Czech Republic, Finland, Germany, Poland, Spain, Switzerland, with additional contributions from the United States and Japan.The French contribution to X-IFU is funded by CNES, CNRS and CEA. This work has been also supported by ASI (Italian Space Agency) through the Contract 2019-27-HH.0, and by the ESA (European Space Agency) Core Technology Program (CTP) Contract No. 4000114932/15/NL/BW and the AREMBES - ESA CTP No.4000116655/16/NL/BW. This publication is part of grant RTI2018-096686-B-C21 funded by MCIN/AEI/10.13039/501100011033 and by “ERDF A way of making Europe”. This publication is part of grant RTI2018-096686-B-C21 and PID2020-115325GB-C31 funded by MCIN/AEI/10.13039/501100011033

The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases

The SIB Swiss Institute of Bioinformatics (www.isb-sib.ch) provides world-class bioinformatics databases, software tools, services and training to the international life science community in academia and industry. These solutions allow life scientists to turn the exponentially growing amount of data into knowledge. Here, we provide an overview of SIB's resources and competence areas, with a strong focus on curated databases and SIB's most popular and widely used resources. In particular, SIB's Bioinformatics resource portal ExPASy features over 150 resources, including UniProtKB/Swiss-Prot, ENZYME, PROSITE, neXtProt, STRING, UniCarbKB, SugarBindDB, SwissRegulon, EPD, arrayMap, Bgee, SWISS-MODEL Repository, OMA, OrthoDB and other databases, which are briefly described in this article

European common frog (Rana temporaria) recolonized Switzerland from multiple glacial refugia in northern Italy via trans‐ and circum‐Alpine routes

The high mountain ranges of Western Europe had a profound effect on the biotic recolonization of Europe from glacial refugia. The Alps present a particularly interesting case because they form an absolute barrier to dispersal for most taxa, obstructing recolonization from multiple refugia in northern Italy. Here, we investigate the effect of the European Alps on the phylogeographic history of the European common frog Rana temporaria. Based on partial cytochrome b and COXI sequences from Switzerland, we find two mitochondrial lineages roughly north and south of the Alpine ridge, with contact zones between them in eastern and western Switzerland. The northern haplogroup falls within the previously identified Western European haplogroup, while the southern haplogroup is unique to Switzerland. We find that the lineages diverged ~110 kya, at approximately the onset of the last glacial glaciation; this indicates that they are from different glacial refugia. Phylogenetic analyses suggest that the northern and southern haplogroups colonized Switzerland via trans- and circum-Alpine routes from at least two separate refugia in northern Italy. Our results illustrate how a complex recolonization history of the central European Alps can arise from the semi-permeable barrier created by high mountains

Les communautés microbiennes associées à la semence de haricot - A mécanisme d'adaptation locale des plantes?

peer reviewedThe effects of crop genotype and cultivation site on microbial communities associated to seed of Phaseolus vulgaris were assessed on 33 seed lots. These seed lots were obtained by multiplying 5 initial seed lots of different cultivars in two contrasting environments for 2 years in 3 replicates. An additional commercial control lot was introduced the second year. The diversity of fungal and bacterial communities was analyzed by high-throughput sequencing of the bacterial 16S rRNA gene and the fungal ITS1 region, respectively. Results showed that the structure of the fungal and the bacterial communities is significantly affected by the cultivation site

Carbon nanotubes alter agrosystem multifunctionality

International audienceSince the discovery of the potential of carbon nanotubes (CNTs) in agriculture to improve crop yield, many studies have been conducted to understand which effects CNTs could have on agrosystem components. However, to date, very little is known about their impacts on ecosystem functions such as biogeochemical cycles or primary production and consequently on the multifunctionality of agrosystems. In this study, we aimed at understanding the impact of CNTs in microcosms including soil bacteria and a crop plant (maize) with a special focus on H2O, C and N cycles as well as crop nutrition and resistance. After a 6-week exposure, bacterial concentration was increased by 82% in soils exposed to 10 mg kg−1; in parallel, the organic matter decomposition rate was also significantly enhanced. An increase of nitrifier abundance was quantified with archaeal amoA gene copy numbers reaching +144% in soils exposed to 10 mg kg−1 of CNTs.Maize exposed to 0.1 mg kg−1 of CNTs had in average 34%, 18% and 12% lower chlorophyll, tannin and phenolic compounds, respectively but no impact was detected on the biomass production. Maize plants were water-stressed after exposure to 10 mg kg−1 of CNTs with a significant 17% increase of the dry matter compared to unexposed maize. CNT exposure also led to a significant decrease of H2O flux in the system.As a result, the multifunctionality of the agrosystem was significantly decreased at 0.1 mg kg−1. Structural equation modeling suggested that CNT impact on bacteria population in general, and on bacteria implied in denitrification and CO2 emission were the main factors influencing the multifunctionality index