23,247 research outputs found
Securing a Quantum Key Distribution Network Using Secret Sharing
We present a simple new technique to secure quantum key distribution relay
networks using secret sharing. Previous techniques have relied on creating
distinct physical paths in order to create the shares. We show, however, how
this can be achieved on a single physical path by creating distinct logical
channels. The technique utilizes a random 'drop-out' scheme to ensure that an
attacker must compromise all of the relays on the channel in order to access
the key
Extending the Reach of QKD Using Relays
One of the obstacles to deployment of QKD solutions has been the distance
limitation. Solutions using relays have been proposed but these rely on
link-by-link key establishment. We present a new technique to extend the
distance of a quantum key distribution channel using an active relay. Each
relay acts as an intercept/resend device and allows the establishment of an
end-to-end key. It has been argued that such relays cannot be used to extend
the distance, but we show that with a suitable adaptation of the protocol the
effective key distribution distance can be increased
Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model
<b>Background and Purpose</b><p></p>
cAMP and pharmacological inhibition of PDE4, which degrades it, are promising therapeutic targets for the treatment of spinal cord injury (SCI). Using our previously described in vitro SCI model, we studied the mechanisms by which cAMP modulators promote neurite outgrowth and myelination using enantiomers of the PDE4-specific inhibitor rolipram and other modulators of downstream signalling effectors.<p></p>
<b>Experimental Approach</b><p></p>
Rat mixed neural cell myelinating cultures were cut with a scalpel and treated with enantiomers of the PDE4-specific inhibitor rolipram, Epac agonists and PKA antagonists. Neurite outgrowth, density and myelination were assessed by immunocytochemistry and cytokine levels analysed by qPCR.<p></p>
<b>Key Results</b><p></p>
Inhibition of the high-affinity rolipram-binding state (HARBS), rather than the low-affinity rolipram binding state (LARBS) PDE4 conformer promoted neurite outgrowth and myelination. These effects were mediated through the activation of Epac and not through PKA. Expression of the chemokine CXCL10, known to inhibit myelination, was markedly elevated in astrocytes after Rho inhibition and this was blocked by inhibition of Rho kinase or PDE4.<p></p>
<b>Conclusions and Implications</b><p></p>
PDE4 inhibitors targeted at the HARBS conformer or Epac agonists may provide promising novel targets for the treatment of SCI. Our study demonstrates the differential mechanisms of action of these compounds, as well as the benefit of a combined pharmacological approach and highlighting potential promising targets for the treatment of SCI. These findings need to be confirmed in vivo
Retrodiction as a tool for micromaser field measurements
We use retrodictive quantum theory to describe cavity field measurements by
successive atomic detections in the micromaser. We calculate the state of the
micromaser cavity field prior to detection of sequences of atoms in either the
excited or ground state, for atoms that are initially prepared in the excited
state. This provides the POM elements, which describe such sequences of
measurements.Comment: 20 pages, 4(8) figure
Temperature dependence of the average electron-hole pair creation energy in Al0.8Ga0.2As
The temperature dependence of the average energy consumed in the creation of an electron-hole pair in the wide bandgap compound semiconductor Al 0.8Ga0.2As is reported following X-ray measurements made using an Al0.8Ga0.2As photodiode diode coupled to a low-noise charge-sensitive preamplifier operating in spectroscopic photon counting mode. The temperature dependence is reported over the range of 261 K-342 K and is found to be best represented by the equation ε AlGaAs 7.327-0.0077 T, where εAlGaAs is the average electron-hole pair creation energy in eV and T is the temperature in K. © 2013 © 2013 Author(s)
Quantum local-field corrections and spontaneous decay
A recently developed scheme [S. Scheel, L. Knoll, and D.-G. Welsch, Phys.
Rev. A 58, 700 (1998)] for quantizing the macroscopic electromagnetic field in
linear dispersive and absorbing dielectrics satisfying the Kramers-Kronig
relations is used to derive the quantum local-field correction for the standard
virtual-sphere-cavity model. The electric and magnetic local-field operators
are shown to be consistent with QED only if the polarization noise is fully
taken into account. It is shown that the polarization fluctuations in the local
field can dramatically change the spontaneous decay rate, compared with the
familiar result obtained from the classical local-field correction. In
particular, the spontaneous emission rate strongly depends on the radius of the
local-field virtual cavity.Comment: 7 pages, using RevTeX, 4 figure
On the Quantum Phase Operator for Coherent States
In papers by Lynch [Phys. Rev. A41, 2841 (1990)] and Gerry and Urbanski
[Phys. Rev. A42, 662 (1990)] it has been argued that the phase-fluctuation
laser experiments of Gerhardt, B\"uchler and Lifkin [Phys. Lett. 49A, 119
(1974)] are in good agreement with the variance of the Pegg-Barnett phase
operator for a coherent state, even for a small number of photons. We argue
that this is not conclusive. In fact, we show that the variance of the phase in
fact depends on the relative phase between the phase of the coherent state and
the off-set phase of the Pegg-Barnett phase operator. This off-set
phase is replaced with the phase of a reference beam in an actual experiment
and we show that several choices of such a relative phase can be fitted to the
experimental data. We also discuss the Noh, Foug\`{e}res and Mandel [Phys.Rev.
A46, 2840 (1992)] relative phase experiment in terms of the Pegg-Barnett phase
taking post-selection conditions into account.Comment: 8 pages, 8 figures. Typographical errors and misprints have been
corrected. The outline of the paper has also been changed. Physica Scripta
(in press
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