65 research outputs found

    Open- and closed-system characteristics of a tilted plutonic system, Klamath Mountains, California

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    The Wooley Creek batholith and Slinkard pluton are adjacent plutons with identical U-Pb zircon ages of 161 +4/−2 Ma. The plutons dip toward each other, which suggests that they are connected in the subsurface. Geologic and thermochemical evidence shows that the Slinkard pluton is the structurally lowest part of the system and the Wooley Creek batholith the structurally highest, with a total structural relief of at least 15 km. The wall rocks adjacent to the highest level of the Wooley Creek batholith are intruded by mafic to felsic dikes derived from the subjacent pluton. The Slinkard pluton is predominantly quartz diorite but grades from two-pyroxene diorite to sparse muscovite-biotite granite and shows little evidence of contamination except near contacts. The Wooley Creek batholith grades upward from two-pyroxene gabbro to biotite-hornblende granite and has a central zone in which injected mafic magma was trapped and mixed. Major and trace element data are consistent with closed-system fractionation of the Slinkard pluton and lower (adjacent) Wooley Creek batholith, but with open-system differentiation of the upper Wooley Creek batholith and roof-zone dikes. Andesitic roof-zone dikes show trace element enrichment similar to the central mixed zone of the Wooley Creek batholith and may have differentiated at that central level of the system

    Timing of sedimentation, metamorphism, and plutonism in the Helgeland Nappe Complex, north-central Norwegian Caledonides

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    The Helgeland Nappe Complex consists of a sequence of imbricated east-dipping nappes that record a history of Neoproterozoic- Ordovician, sedimentary, metamorphic, and magmatic events. A combination of U-Pb dating of zircon and titanite by laser-ablation- inductively coupled plasma-mass spectrometry plus chemostratigraphic data on marbles places tight constraints on the sedimentary, tectonic, and thermal events of the complex. Strontium and carbon isotope data have identifi ed Neoproterozoic marbles in the Lower Nappe, the Horta nappe, and Scandian-aged infolds in the Vikna region. The environment of deposition of these rocks was a continental shelf, presumably of Laurentia. Detrital zircon ages from the Lower Nappe are nearly identical to those of Dalradian sedimentary rocks in Scotland. Cambrian rifting caused development of one or more ophiolitefl oored basins, into which thick sequences of Early Ordovician clastic and carbonate sediments were deposited. On the basis of ages of the youngest zircons, deposition ended after ca. 481 Ma. These basin units are now seen as the Skei Group, Sauren-Torghatten Nappe, and Middle Nappe, as well as the stratigraphically highest part of the Horta nappe and possibly of the Upper Nappe. The provenance of these sediments was partly from the Lower Nappe, on the basis of detrital zircon age populations in metasandstones and cobbles from proximal conglomerates. However, the source of Cambrian-Ordovician zircons in all of the Early Ordovician basins is enigmatic. Crustal anatexis of the Lower and Upper Nappes occurred ca. 480 Ma, followed by imbrication of the entire nappe sequence. By ca. 478 Ma, the Horta nappe was overturned and was at the structural base of the nappe sequence, where it underwent migmatization and was the source of S-type magmas. Diverse magmatic activity followed ca. 465 Ma, 450-445 Ma, and 439-424 Ma. Several plutons in the youngest age range contain inherited 460-450 Ma zircons. These zircons are interpreted to refl ect a deep crustal zone in which mafi c magmas caused melting, mixing, and hybridization from 460 to 450 Ma. Magmatic reheating of this zone, possibly associated with crustal thickening, resulted in voluminous, predominantly tonalitic magmatism from 439 to 424 Ma

    The Grand Tour of the Ruby-East Humboldt Metamorphic Core Complex, Northeastern Nevada: Part 1-Introduction & Road Log

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    The purpose of this geological excursion is to provide an overview of the multiphase developmental history of the Ruby Mountains and East Humboldt Range, northeastern Nevada. Although these mountain ranges are commonly cited as a classic example of a Cordilleran metamorphic core complex developed through large-magnitude, mid-Tertiary crustal extension, a preceding polyphase Mesozoic contractional history is also well preserved in the ranges. An early phase of this history involved Late Jurassic two-mica granitic magmatism, high-temperature but relatively low-pressure metamorphism, and polyphase deformation in the central Ruby Mountains. In the northern Ruby Mountains and East Humboldt Range, a Late Cretaceous history of crustal shortening, metamorphism, and magmatism is manifested by fold-nappes (involving Archean basement rocks in the northern East Humboldt Range), widespread migmatization, injection of monzogranitic and leucogranitic magmas, all coupled with sillimanite-grade metamorphism. Following Late Cretaceous contraction, a protracted extensional deformation partially overprinted these areas during the Cenozoic. This extensional history may have begun as early as the Late Cretaceous or as late as the mid-Eocene. Late Eocene and Oligocene magmatism occurred at various levels in the crust yielding mafic to felsic orthogneisses in the deep crust, a composite granitic pluton in the upper crust, and volcanic rocks at the surface. Movement along a west-rooted, extensional shear zone in the Oligocene and early Miocene led to core-complex exhumation. The shear zone produced mylonitic rocks about 1 km thick at deep crustal levels, and an overprint of brittle detachment faulting at shallower levels as unroofing proceeded. Megabreccias and other synextensional sedimentary deposits are locally preserved in a tilted, upper Eocene through Miocene stratigraphic sequence. Neogene magmatism included the emplacement of basalt dikes and eruption of rhyolitic rocks. Subsequent Basin and Range normal faulting, as young as Holocene, records continued tectonic extension

    Effect of a web-based chronic disease management system on asthma control and health-related quality of life: study protocol for a randomized controlled trial

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    <p>Abstract</p> <p>Background</p> <p>Asthma is a prevalent and costly disease resulting in reduced quality of life for a large proportion of individuals. Effective patient self-management is critical for improving health outcomes. However, key aspects of self-management such as self-monitoring of behaviours and symptoms, coupled with regular feedback from the health care team, are rarely addressed or integrated into ongoing care. Health information technology (HIT) provides unique opportunities to facilitate this by providing a means for two way communication and exchange of information between the patient and care team, and access to their health information, presented in personalized ways that can alert them when there is a need for action. The objective of this study is to evaluate the acceptability and efficacy of using a web-based self-management system, My Asthma Portal (MAP), linked to a case-management system on asthma control, and asthma health-related quality of life.</p> <p>Methods</p> <p>The trial is a parallel multi-centered 2-arm pilot randomized controlled trial. Participants are randomly assigned to one of two conditions: a) MAP and usual care; or b) usual care alone. Individuals will be included if they are between 18 and 70, have a confirmed asthma diagnosis, and their asthma is classified as not well controlled by their physician. Asthma control will be evaluated by calculating the amount of fast acting beta agonists recorded as dispensed in the provincial drug database, and asthma quality of life using the Mini Asthma Related Quality of Life Questionnaire. Power calculations indicated a needed total sample size of 80 subjects. Data are collected at baseline, 3, 6, and 9 months post randomization. Recruitment started in March 2010 and the inclusion of patients in the trial in June 2010.</p> <p>Discussion</p> <p>Self-management support from the care team is critical for improving chronic disease outcomes. Given the high volume of patients and time constraints during clinical visits, primary care physicians have limited time to teach and reinforce use of proven self-management strategies. HIT has the potential to provide clinicians and a large number of patients with tools to support health behaviour change.</p> <p>Trial Registration</p> <p>Current Controlled Trials <a href="http://www.controlled-trials.com/ISRCTN34326236">ISRCTN34326236</a>.</p

    Acupuncture and chiropractic care for chronic pain in an integrated health plan: a mixed methods study

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    <p>Abstract</p> <p>Background</p> <p>Substantial recent research examines the efficacy of many types of complementary and alternative (CAM) therapies. However, outcomes associated with the "real-world" use of CAM has been largely overlooked, despite calls for CAM therapies to be studied in the manner in which they are practiced. Americans seek CAM treatments far more often for chronic musculoskeletal pain (CMP) than for any other condition. Among CAM treatments for CMP, acupuncture and chiropractic (A/C) care are among those with the highest acceptance by physician groups and the best evidence to support their use. Further, recent alarming increases in delivery of opioid treatment and surgical interventions for chronic pain--despite their high costs, potential adverse effects, and modest efficacy--suggests the need to evaluate real world outcomes associated with promising non-pharmacological/non-surgical CAM treatments for CMP, which are often well accepted by patients and increasingly used in the community.</p> <p>Methods/Design</p> <p>This multi-phase, mixed methods study will: (1) conduct a retrospective study using information from electronic medical records (EMRs) of a large HMO to identify unique clusters of patients with CMP (e.g., those with differing demographics, histories of pain condition, use of allopathic and CAM health services, and comorbidity profiles) that may be associated with different propensities for A/C utilization and/or differential outcomes associated with such care; (2) use qualitative interviews to explore allopathic providers' recommendations for A/C and patients' decisions to pursue and retain CAM care; and (3) prospectively evaluate health services/costs and broader clinical and functional outcomes associated with the receipt of A/C relative to carefully matched comparison participants receiving traditional CMP services. Sensitivity analyses will compare methods relying solely on EMR-derived data versus analyses supplementing EMR data with conventionally collected patient and clinician data.</p> <p>Discussion</p> <p>Successful completion of these aggregate aims will provide an evaluation of outcomes associated with the real-world use of A/C services. The trio of retrospective, qualitative, and prospective study will also provide a clearer understanding of the decision-making processes behind the use of A/C for CMP and a transportable methodology that can be applied to other health care settings, CAM treatments, and clinical populations.</p> <p>Trial registration</p> <p>ClinicalTrials.gov: <a href="http://www.clinicaltrials.gov/ct2/show/NCT01345409">NCT01345409</a></p

    The western hayfork terrane: Remnants of the Middle Jurassic arc in the Klamath Mountain province, California and Oregon

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    © 2020 The Authors. cc-by-ncArc magmatism was widespread in the Cordillera of North America during Middle Jurassic time. The predominant representative of this arc magmatism in the Klamath Mountain province is the western Hayfork terrane (WHT). This terrane is primarily metasedimentary, consisting mainly of crystal-lithic arenite, argillitic sediments and lahar deposits, rare lavas, and sparse quartz-rich arenite. Because lavas are rare, petrologic study using bulk-rock compositions is restricted to analysis of cobbles in lahar deposits. Moreover, the WHT underwent greenschist-facies regional metamorphism with consequent modification of bulk-rock compositions. However, many of the sandstones preserve igneous clinopyroxene and calcic amphibole, which were phenocrysts in the original volcanic rocks. Major-and trace-element compositions of the magmatic pyroxene and amphibole permit reconstruction of the range of rock types eroded from the arc, specifically scant basalt, volumetrically dominant basaltic andesite and andesite, and smaller but significant amounts of dacite and rhyodacite. Eruptive temperatures reached ~1180 °C and may have been as low as ~800 °C on the basis of pyroxene and amphibole thermometry, with most eruptive temperatures 1000 °C. On the basis of augite compositions, WHT magmatism is divided into two suites. One features high-Mg augite with high abundances of Cr and Sr, high Sr/Y and Nd/Yb values, and low Y and heavy rare-earth elements (REE). These compositions are typical of high-Mg andesite and dacite suites in which garnet is a residual mineral, most probably in a metasomatized upper mantle setting. The other suite contains augite with lower Sr, Sr/Y, and Nd/Yb; these features are typical of normal calc-alkaline magmas. Augite from a coeval pluton emplaced inboard of the western Hayfork outcrop belt is similar to augite from the low-Sr group of WHT samples. In contrast, augite from the Ironside Mountain pluton, previously considered the plutonic equivalent of WHT sediments, is Fe-rich, with low Cr and Sr and relatively high Zr and REE. Previous suggestions that the Ironside Mountain pluton is correlative with the WHT are not supported by these data. The magmatic diversity of the WHT is typical of the modern Aleutian and Cascade arcs, among others, and could reflect subduction of relatively young oceanic lithosphere or fragmentation of the subduction slab. Although we favor the former setting, present data cannot rule out the latter. The presence of scant quartz-rich sedimentary rocks within the predominantly volcanogenic WHT is consistent with deposition as a sedimentary apron associated with a west-facing magmatic arc with late-stage input from cratonal sources. The results of this study indicate that detailed petrographic study of arc-derived sedimentary rocks, including major-and trace-element analysis of preserved magmatic phases, yields information about magmatic affinities, processes, and temperatures
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