30 research outputs found
Screening and identification of human ZnT8-specific single-chain variable fragment (scFv) from type 1 diabetes phage display library
Full text linkSq and EEJ—A Review on the Daily Variation of the Geomagnetic Field Caused by Ionospheric Dynamo Currents
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On the use of combinatorial antibody libraries to clone the "fossil record" of an individual's immune response
No full textFor about the last century the record of
immunological events could only be obtained from serum
proteins. We suggest that in the future this will change and the
far more detailed nucleic acid record will provide new insights
into immunological processes as well as selective access to the
complete repertoire
Linkage of recognition and replication functions by assembling combinatorial antibody Fab libraries along phage surfaces
No full textWe describe a method based on a phagemid
vector with helper phage rescue for the construction and rapid
analysis of combinatorial antibody Fab libraries. This approach
should allow the generation and selection of many
monoclonal antibodies. Antibody genes are expressed in concert
with phage morphogenesis, thereby allowing incorporation
of functional Fab molecules along the surface of ifiamentous
phage. The power of the method depends upon the
linkage of recognition and replication functions and is not
limited to antibody molecules
Rabbit immune repertoires as sources for therapeutic monoclonal antibodies: the impact of kappa allotype-correlated variation in cysteine content on antibody libraries selected by phage display.
No full textPreparation of peptide-targeted phagemid particles using a protein III-modified helper phage
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