2,053 research outputs found
Integrating Mathematical Thinking Into Family Engagement Programs
The brief explains how exposing young children to early math concepts supports their development of reasoning and problem solving skills and later success in and out of school. It describes the unique ways each of five family engagement programs funded by the Heising-Simons Foundation developed, tested, and integrated early math learning into their usual activities. The brief lays out seven practical tips that emerged from the grantees' experiences that can guide practitioners and other stakeholders who are interested in integrating early math into their own family engagement programs, and sheds light on issues that programs may want to keep in mind while doing so.
Sport Discontinuation: An Assessment of Goal Achievement via Empirical Measures
Collegiate athletic teams are being eliminated at an alarming rate; however, empirical research of athletic spending and participation after these cuts occur is lacking. This study compared whether the proffered rationales for discontinuing teams were consistent with the measurable budgetary and participation outcomes. From a sample of NCAA Division I institutions that discontinued at least one team between the academic years 2000-01 and 2008-09 (N = 125), a total of 49 schools with documented cut rationales were identified. The EADA cutting tool was then used to examine athletic revenues, expenses, and participation numbers from the year prior and the year after the cuts to determine, via descriptive statistics and paired t-tests, if the stated objectives were met. The three reasons primarily cited for the program elimination included: reducing athletic spending (44.9%), reallocating resources (42.9%), and Title IX compliance (18.4%). Statistical analysis revealed that only institutions citing reallocation of athletic resources were able to achieve their stated goals. Institutions citing efforts to reduce athletic spending had significant increases in athletic expenses and none of the institutions citing Title IX compliance achieved substantial proportionality. These results show a troubling disconnection between the elimination rationale and the budgetary and participation outcomes that is worthy of additional investigation
Living with a partner with dementia:a systematic review and thematic synthesis of spouses' lived experiences of changes in their everyday lives
ABSTRACTObjectives: Dementia causes dramatic changes in everyday-living for spouses. Occured changes in marital relationship, force spouses to perform more both mentally and physically. Leading to a spousal perceived burden. To improve understanding of spouses’ needs, spouses lived experiences is needed. The aim was to identify and synthesise qualitative studies on spouses’ lived experiences of living with a partner with dementia.Methods: A systematic search was undertaken in January 2017. Six databases (CINAHL, Cochrane Library, Embase, PubMed, PsycINFO and Sociological Abstracts) were searched, using search terms in accordance with PICo. A descriptive synthesis and a thematic synthesis were undertaken.Findings: Fifteen studies met the inclusion criteria. Three themes derived from the analysis 1) Noticing changes in everyday life 2) Transformation to a new marital relation in everyday life, withcorresponding sub-themes; changes in marital relationship, management of the transitioned marital relation in everyday life 3) Planning the future.Conclusion: Findings provide an overview of how spouses notice changes and transform their marital relationships in everyday-life. Findings offer a deeper understanding of changes that occurs over time while the partner is living at home. Findings contribute with knowledge on spouses’ experiences of changes in early-stages of dementia. Interventions supporting spouses are needed
p53 mutations in phenacetin-associated human urothelial carcinomas
Chronic abuse of the analgesic drug phenacetin is associated with an increased risk of development of transitional cell carcinomas of the urinary tract. It is unclear whether phenacetin acts through chronic tissue damage (phenacetin nephropathy) or via a genotoxic metabolite causing promutagenic DNA lesions. In the present study, we investigated 15 urothelial carcinomas from 13 patients with evidence of phenacetin abuse. Tumors were screened for p53 mutations in exons 5-8 by single-strand conformation polymorphism (SSCP) analysis, followed by direct sequencing of PCR-amplified DNA. p53 Mutations were detected in 8/14 primary tumors (57%). All except one were missense mutations located in exon 5 (three mutations), exon 6 (one), exon 7 (two) and exon 8 (one). The type of mutation varied, with a preference for CpG sites. A frameshift mutation resulting from the insertion of a single cytosine at codons 151/152 was detected in a bladder tumor and its lung metastasis. Urothelial carcinomas located in the renal pelvis and in the ureter of the same patient exhibited two different mutations, strongly suggesting that they developed independently. Another patient had tumors in the renal pelvis and bladder, both of which contained the same p53 mutation, indicating intracavitary metastatic spread. This demonstrates that screening of p53 mutations allows the clonal origin of tumors in patients with multiple primary and metastatic lesions to be determined. None of the tumors investigated contained mutations in codons 12, 13 or 61 of H-ras or K-ras protooncogene
Habitat Management for Northern Bobwhites in Wisconsin: A Long-Term Assessment
An experimental habitat management program was initiated to improve the carrying capacity for northern bobwhites ( Colinus virginianus) on private lands by the Wisconsin Department of Natural Resources (WDNR) in 1974. During 1975-80, extensive habitat restoration was undertaken on a 60-mi2 (l55-km 2) study area in Richland County to restore hedge row cover, improve riparian corridors and woodlot edges, and construct plots of food and shelter to function as wintering sites for bobwhites. Previous investigations in Wisconsin have documented that the long-term decline of bobwhites was the result of habitat deterioration, principally hedgerow cover. Elsewhere, continuous declines in bobwhite abundance suggest a re-evaluation of the validity of time-honored habitat management practices is in order. Therefore, it seemed appropriate to test the impact of extensive attempts at habitat restoration, especially the development of hedgerows, on one small treatment area in the northern fringe of the geographic range of the northern bobwhite. After 10-15 years of growth, only 25% of the planted hedges were found to be effective for wintering bobwhites (i.e., closed canopies and producing fruits). Planted hedgerow cover suffered from poor survival due to deer browsing, competition from other surrounding vegetation, and changes in property owners and attitudes as farms were sold. Linear brushy cover was measured in 1990 and compared to similar estimates from 1978. During the 12-year span, brushy linear cover, including project hedges, decreased by 41% (5,995 to 3,545 yards/square mile; 2,531 to 1,497 meters/square kilometer). In addition, managed winter food resources after 1980 were reduced by half compared to earlier efforts. Through 1991, bobwhite population trends on the treatment area did not differ from statewide trends, indicating that extensive habitat restoration work had no discernible impact with respect to reversing population declines. Over 60% of the annual variability in bobwhite abundance in Richland County is related to the severity of winters. Despite these results, we still cannot discount the value of managing for hedgerows in Wisconsin. Achievements of this project include: (I) developing a bobwhite management strategy on a landscape scale, (2) gaining a high level of landowner cooperation, and (3) implementing an extensive amount of habitat restoration on private agricultural lands at minimal costs. The major problem with our overall approach is that such habitat restoration work requires continuous attention and maintenance over time to maintain effectiveness. Landowners, while highly cooperative, are not interested in protecting or maintaining habitat improvements for wildlife unless they have a vested stake in the project (i.e., a sense of ownership ). Habitat restoration on private agricultural lands necessitates first working to change landowner attitudes towards wildlife, with the development of private lands habitat programs as a secondary concern. The outlook for northern bobwhites in the northern fringe of their range is not bright. Northern bobwhite populations will not recover unless they become a by-product of the contemporary agricultural landscape. Unfortunately, this is not the case in Wisconsin and it is unlikely to change in the foreseeable future
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