Compare the effect of Consumption CoQ10 Supplement on aerobic power, anaerobic and Muscle soreness in athletes and non athletes

زمینه و هدف: کوآنزیم Q10 یک ماده شبه ویتامین محلول در چربی است که حامل ضروری الکترون در میتوکندری می باشد و در تولید انرژی و فعالیت ضد اکسیدانی، نقش مهمی بر عهده دارد. هدف این مطالعه پژوهشی نیمه تجربی، مقایسه اثر مکمل کوآنزیم Q10 بر توان هوازی، بی هوازی و برخی از شاخص های منتخب کوفتگی عضلانی تأخیری پسران ورزشکار و غیر ورزشکار بود. روش بررسی: 60 پسر دانش آموز داوطلب، به روش نمونه در دسترس انتخاب که از بین آن ها و به طور تصادفی 20 نفر با میانگین سن، قد و وزن به ترتیب (80/0±30/16 سال، 6±172 سانتی متر، 55/7±76/62 کیلوگرم) انتخاب که در دو گروه ورزشکار (10 =n) و غیر ورزشکار (10 =n) طبقه بندی شدند. از هر دو گروه 4 مرتبه خونگیری (هر بار 5 سی سی مایع از ورید پیش آرنجی) طی دو مرحله (قبل و بعد از مکمل دهی) به عمل آمد که سطح پایه و تغییرات شاخص های کوفتگی تأخیری (LDH و CK)، با کیت آزمایشگاهی پارس آزمون و با دستگاه اتوآنالایزر AT- آلفا کلاستیک مورد ارزیابی قرار گرفت. قراردادهای ورزشی پژوهش، بروس (با استفاده از نوارگردان، جهت ارزیابی VO2max) و فالکنر (با استفاده از نوارگردان- 9/12 V= کیلومتر بر ساعت و 20 g=، جهت ارزیابی توان بی هوازی) بود. ضریب پایایی آزمون بروس و فالکنر به ترتیب در حدود 95/0 تا 99/0 و 76/0 تا 91/0 است. جهت بررسی تفاوت در مراحل مختلف نمونه گیری، تفاوت های درون گروهی و برون گروهی، از آزمون های آنالیز تحلیل واریانس (ANOVA)، SPSS، تی وابسته و تی مستقل در سطح معنی داری 05/0≥P استفاده شد. یافته ها: یافته های پژوهش نشان داد که مصرف کوتاه مدت مکمل CoQ10 منجر به عدم تغییر معنی دار CK (19/0P=)، LDH (12/0P=)، توان بی هوازی (17/0P=) و توان هوازی (43/0P=) هر دو گروه ورزشکار و غیر ورزشکار شد. نتیجه گیری: به طور کلی نتایج بیانگر این بودند که سطح آمادگی بدنی (مقایسه ورزشکار یا غیر ورزشکار بودن)، تأثیری در اثر مکمل کوآنزیم Q10 بر توان هوازی، بی هوازی و کوفتگی عضلانی نداشت و هر دو گروه به یک اندازه از مکمل بهره بردند

Effect of Aloe vera on some indicators of cell damage after a period of aerobic exercise in male athletes

Introduction: Aloe vera is a medicinal plant with antioxidant activity. The purpose of this study was to determine the effect of Aloe vera on some indicators of cell damage after a period of aerobic exercise in male athletes of 15-18 years old. Methods: In this clinical trial study, 20 male students with average weight of 64.85 &plusmn; 51 and height of 172.05 &plusmn; 6.4 were randomly assigned to 2 groups of Aloe vera supplement (n = 10) and placebo (n = 10). Then aerobic training was conducted for 4 weeks. The supplemented group took 3 capsules, each capsule contains 2 g of dried Aloe vera and placebo group took 3 capsules/day containing dextran after every meal. To determine the index of cell injury markers creatine kinase (CK), lactate dehydrogenase (LDH) and reactive protein C (CRP) were determined and blood samples were collected 24 hours before and after each test. The data were analyzed using ANOVA and independent t test. Significance level was considered as P &le; .05. Results: The use of Aloe vera during aerobic exercise significantly reduced LDH (P = .006) in the supplement group (15 reduction) compared to placebo group and CRP with 11 reduction in the supplement group compared to placebo (P = .008). There was no significant reduction in CK. Conclusion: The findings of this study showed that Aloe vera reduces cell damage and inflammation indicators. This result may reflect the role of Aloe vera as anti-inflammatory and antioxidant agent.</p

Determining the effect of aloe Vera and aerobic exercise on lactate de-hydrogenase in male athletes

Aloe Vera is a medicinal plant as antioxidants reduce cell damage and used. The purpose of this study was to determine the effect of Aloe Vera on lactate de-hydrogenase after a period of aerobic exercise in male athletes. Methods This study applied the method according to the nature of the study, based on semi-empirical research and a review of the pre-test, post-test supplements and placebo groups, respectively. In this study,20 male students weight was 64.85 ± .51 and height was 172.05 ± 6.4 were randomly assigned to two groups of Imam Ali College of Physical Education Supplement (n = 10) and placebo (10 people). Then aerobic training was conducted for 4 weeks in the supplemented group were taking 3 capsules, each capsule contains 2 grams of dried Aloe Vera and placebo group were taking 3 capsules containing Dextrin daily after every meal. To determine the index of LDH were used and blood samples were collected 24 hours before and after each test Cooper with student in the lab. To describe data, analytical data, and for the mean and standard deviation of repeated measures ANOVA and independent T-test was used for comparison between groups Significance level was P ≤ 0.05. The use of Aloe Vera during aerobic exercise significantly, cautious reduced LDH (P=0.006) in the supplement group compared to placebo was 15 reduction. Conclusion: Overall the findings of this study showed that Aloe Vera reduces lactate de-hydrogenase. This result may reflect the role of Aloe Vera has anti-inflammatory and antioxidant

Effects of fatigue on electromyography activity of biceps femoris, gastrocnemius and soleus muscles of soccer players

Introduction: The aim of this study was to investigate the effect of fatigue on electromyography activity of biceps femoris, gastrocnemius and soleus muscles of soccer players. Materials and Methods: In this study timing and electromyography activity of biceps femoris, medial gastrocnemius and soleus of soccer players (15 subjects) during different times of football were investigated. Surface electromyography (ME6000) was used to collect data during single leg drop (before the game, after the first and the second half time). Results: Results of this study showed that although fatigue affects muscle's timing but in different periods of time it wasn�t significant (P>0.05). Conspiciously, significant differences were observed for feedforward activity of biceps femoris and soleus (P�0.05), but for medial gastrocnemius it wasn't significant (P>0.05). Also significant differences were observed for feedback activity of soleus muscles (P�0.05), but it wasn�t significant for biceps femoris and medial gastrocnemius (P>0.05). Conclusion: It can be concluded that fatigue leads to insignificant changes in timing but there were significant differences for feed forward activity of biceps femoris and soleus and feedback activity of soleus. So, during training sessions, trainers should be trying to improve player's tolerance and prevent soccer injuries. © 2019, Semnan University of Medical Sciences. All rights reserved

Tracking development assistance for health and for COVID-19 : a review of development assistance, government, out-of-pocket, and other private spending on health for 204 countries and territories, 1990-2050

Background The rapid spread of COVID-19 renewed the focus on how health systems across the globe are financed, especially during public health emergencies. Development assistance is an important source of health financing in many low-income countries, yet little is known about how much of this funding was disbursed for COVID-19. We aimed to put development assistance for health for COVID-19 in the context of broader trends in global health financing, and to estimate total health spending from 1995 to 2050 and development assistance for COVID-19 in 2020. Methods We estimated domestic health spending and development assistance for health to generate total health-sector spending estimates for 204 countries and territories. We leveraged data from the WHO Global Health Expenditure Database to produce estimates of domestic health spending. To generate estimates for development assistance for health, we relied on project-level disbursement data from the major international development agencies' online databases and annual financial statements and reports for information on income sources. To adjust our estimates for 2020 to include disbursements related to COVID-19, we extracted project data on commitments and disbursements from a broader set of databases (because not all of the data sources used to estimate the historical series extend to 2020), including the UN Office of Humanitarian Assistance Financial Tracking Service and the International Aid Transparency Initiative. We reported all the historic and future spending estimates in inflation-adjusted 2020 US$, 2020 US$ per capita, purchasing-power parity-adjusted US$per capita, and as a proportion of gross domestic product. We used various models to generate future health spending to 2050. Findings In 2019, health spending globally reached$8. 8 trillion (95% uncertainty interval [UI] 8.7-8.8) or $1132 (1119-1143) per person. Spending on health varied within and across income groups and geographical regions. Of this total,$40.4 billion (0.5%, 95% UI 0.5-0.5) was development assistance for health provided to low-income and middle-income countries, which made up 24.6% (UI 24.0-25.1) of total spending in low-income countries. We estimate that $54.8 billion in development assistance for health was disbursed in 2020. Of this,$13.7 billion was targeted toward the COVID-19 health response. $12.3 billion was newly committed and$1.4 billion was repurposed from existing health projects. $3.1 billion (22.4$2.4 billion (17.9%) was for supply chain and logistics. Only $714.4 million (7.7$1519 (1448-1591) per person in 2050, although spending across countries is expected to remain varied. Interpretation Global health spending is expected to continue to grow, but remain unequally distributed between countries. We estimate that development organisations substantially increased the amount of development assistance for health provided in 2020. Continued efforts are needed to raise sufficient resources to mitigate the pandemic for the most vulnerable, and to help curtail the pandemic for all. Copyright (C) 2021 The Author(s). Published by Elsevier Ltd.Peer reviewe

Effect of exercise interventions on movement performance in Parkinson disease

Background: Parkinson disease is a CNS disease of senile characterized with gradual and progressive muscular rigidity, tremor and the loss of locomotor skills. The aim of the present study was to review the exercise/physical interventions relevant to the treatment of idiopathic Parkinson disease. Materials and Methods: This review was done using a systematic search in Sportdi, PubMed, Medline, and Google Scholar cites on papers published during 1995-2013 in the field of training, exercise/movement therapy on Parkinson. Moreover, the review was done in four categories: postural instability, balance performance, quality of life, walking and risk of falling. Results: Despite the diversity in training program, the majority of studies reported significant benefits in addition to the conventional medical treatments on the movement performance in Parkinson's disease. Conclusion: Given the effectiveness of exercise in the improvement of different aspects of movement performance among the Parkinson patients, in future the clinicians are required to take special consideration on applying movement therapy along with medical treatments for specific measurements on the biomechanical aspects of the disease

Comparing the radiographic grading scales, knee pain, signs, movement dysfunctions and the quality of life related to osteoarthritis in ex-elite track and field athletes and non-athletes

Background: The purpose of this study was to compare the radiographic grading scales osteoarthritis, knee pain, signs and movement dysfunctions related to osteoarthritis in daily, sport and recreational activities and also the quality of life between ex-elite track and field athletes and the non-athletes.Materials and Methods: Thirty ex-elite male track and field athletes were purposefully selected and divided into two equal groups (n=15). The clinical and radiological methods (Kellgren-Lawrence) and a global and domestic questionnaire of the knee injury and osteoarthritis outcome score (KOOS) were used to diagnose the disease.Results: Results showed a significant lower mean for movement dysfunctions in sport and recreational activities between athletes and non-athletes (P=0.02). Despite a 30 difference in the mean radiographic grading for osteoarthritis in athletes compared to the non-athletes, the difference was not statistically significant (P=0.90). Moreover, the lower mean values for knee pain, signs, movement dysfunctions in daily activities and the quality of life in athletes were 10 (P=0.27), 10 (P=0.09), 12 (P=0.13) and 4 (P=0.90), respectively compared to non-athletes, however, the difference was not statistically significant.Conclusion: Participating in track and field competitions at the professional level may improve the movement function of ex-elite athletes