6 research outputs found
Counting sub-multisets of fixed cardinality
This report presents an expression for the number of a multiset's
sub-multisets of a given cardinality as a function of the multiplicity of its
elements. This is also the number of distinct samples of a given size that may
be produced by sampling without replacement from a finite population
partitioned into subsets, in the case where items belonging to the same subset
are considered indistinguishable. Despite the generality of this problem, we
have been unable to find this result published elsewhere.Comment: 9 page
BRIO: a web server for RNA sequence and structure motif scan
The interaction between RNA and RNA-binding proteins (RBPs) has a key role in the regulation of gene expression, in RNA stability, and in many other biological processes. RBPs accomplish these functions by binding target RNA molecules through specific sequence and structure motifs. The identification of these binding motifs is therefore fundamental to improve our knowledge of the cellular processes and how they are regulated. Here, we present BRIO (BEAM RNA Interaction mOtifs), a new web server designed for the identification of sequence and structure RNA-binding motifs in one or more RNA molecules of interest. BRIO enables the user to scan over 2508 sequence motifs and 2296 secondary structure motifs identified in Homo sapiens and Mus musculus, in three different types of experiments (PAR-CLIP, eCLIP, HITS). The motifs are associated with the binding of 186 RBPs and 69 protein domains. The web server is freely available at http://brio.bio.uniroma2.it
Arithmetic Upper and Lower Bounds for the Denumerant Function
We use an old elementary arithmetic argument to find new upper and lower
bounds for Sylvester's denumerant function. These bounds are tight enough to
get the asymptotic behavior of the denumerant.Comment: 24 page