33 research outputs found
Capturing Hands in Action using Discriminative Salient Points and Physics Simulation
Hand motion capture is a popular research field, recently gaining more
attention due to the ubiquity of RGB-D sensors. However, even most recent
approaches focus on the case of a single isolated hand. In this work, we focus
on hands that interact with other hands or objects and present a framework that
successfully captures motion in such interaction scenarios for both rigid and
articulated objects. Our framework combines a generative model with
discriminatively trained salient points to achieve a low tracking error and
with collision detection and physics simulation to achieve physically plausible
estimates even in case of occlusions and missing visual data. Since all
components are unified in a single objective function which is almost
everywhere differentiable, it can be optimized with standard optimization
techniques. Our approach works for monocular RGB-D sequences as well as setups
with multiple synchronized RGB cameras. For a qualitative and quantitative
evaluation, we captured 29 sequences with a large variety of interactions and
up to 150 degrees of freedom.Comment: Accepted for publication by the International Journal of Computer
Vision (IJCV) on 16.02.2016 (submitted on 17.10.14). A combination into a
single framework of an ECCV'12 multicamera-RGB and a monocular-RGBD GCPR'14
hand tracking paper with several extensions, additional experiments and
detail
Genomic diversity and signatures of selection in meat and fancy rabbit breeds based on high-density marker data
open6noThe study was funded by the PSRN (Programma di Sviluppo Rurale Nazionale) Cun-Fu and Cun-Fu 2 projects (co-funded by the European Agricultural Fund for Rural Development of the European Union and by the Italian Ministry of Agriculture, Food and Forestry—MiPAAF) and by the University of Bologna RFO 2019 programme.Background: Domestication of the rabbit (Oryctolagus cuniculus) has led to a multi-purpose species that includes many breeds and lines with a broad phenotypic diversity, mainly for external traits (e.g. coat colours and patterns, fur structure, and morphometric traits) that are valued by fancy rabbit breeders. As a consequence of this human-driven selection, distinct signatures are expected to be present in the rabbit genome, defined as signatures of selection or selective sweeps. Here, we investigated the genome of three Italian commercial meat rabbit breeds (Italian Silver, Italian Spotted and Italian White) and 12 fancy rabbit breeds (Belgian Hare, Burgundy Fawn, Champagne d’Argent, Checkered Giant, Coloured Dwarf, Dwarf Lop, Ermine, Giant Grey, Giant White, Rex, Rhinelander and Thuringian) by using high-density single nucleotide polymorphism data. Signatures of selection were identified based on the fixation index (FST) statistic with different approaches, including single-breed and group-based methods, the latter comparing breeds that are grouped based on external traits (different coat colours and body sizes) and types (i.e. meat vs. fancy breeds). Results: We identified 309 genomic regions that contained signatures of selection and that included genes that are known to affect coat colour (ASIP, MC1R and TYR), coat structure (LIPH), and body size (LCORL/NCAPG, COL11A1 and HOXD) in rabbits and that characterize the investigated breeds. Their identification proves the suitability of the applied methodologies for capturing recent selection events. Other regions included novel candidate genes that might contribute to the phenotypic variation among the analyzed breeds, including genes for pigmentation-related traits (EDNRA, EDNRB, MITF and OCA2) and body size, with a strong candidate for dwarfism in rabbit (COL2A1). Conclusions: We report a genome-wide view of genetic loci that underlie the main phenotypic differences in the analyzed rabbit breeds, which can be useful to understand the shift from the domestication process to the development of breeds in O. cuniculus. These results enhance our knowledge about the major genetic loci involved in rabbit external traits and add novel information to understand the complexity of the genetic architecture underlying body size in mammals.openBallan, Mohamad; Bovo, Samuele; Schiavo, Giuseppina; Schiavitto, Michele; Negrini, Riccardo; Fontanesi, LucaBallan, Mohamad; Bovo, Samuele; Schiavo, Giuseppina; Schiavitto, Michele; Negrini, Riccardo; Fontanesi, Luc
CrowdCam: Instantaneous Navigation of Crowd Images Using Angled Graph
We present a near real-time algorithm for interactively exploring a collectively captured moment without explicit 3D reconstruction. Our system favors immediacy and local coherency to global consistency. It is common to represent photos as vertices of a weighted graph, where edge weights measure similarity or distance between pairs of photos. We introduce Angled Graphs as a new data structure to organize collections of photos in a way that enables the construction of visually smooth paths. Weighted angled graphs extend weighted graphs with angles and angle weights which penalize turning along paths. As a result, locally straight paths can be computed by specifying a photo and a direction. The weighted angled graphs of photos used in this paper can be regarded as the result of discretizing the Riemannian geometry of the high dimensional manifold of all possible photos. Ultimately, our system enables everyday people to take advantage of each others' perspectives in order to create on-the-spot spatiotemporal visual experiences similar to the popular bullet-time sequence. We believe that this type of application will greatly enhance shared human experiences spanning from events as personal as parents watching their children's football game to highly publicized red carpet galas.Swiss National Science FoundationEuropean Commission (ERC grant #210806 4DVideo, 7th Framework Programme (FP7/2007- 2013)
Comparative analysis of genomic inbreeding parameters and runs of homozygosity islands in several fancy and meat rabbit breeds
Runs of homozygosity (ROH) are defined as long stretches of DNA homozygous at each polymorphic position. The proportion of genome covered by ROH and their length are indicators of the level and origin of inbreeding. In this study, we analysed SNP chip datasets (obtained using the Axiom OrcunSNP Array) of a total of 702 rabbits from 12 fancy breeds and four meat breeds to identify ROH with different approaches and calculate several genomic inbreeding parameters. The highest average number of ROH per animal was detected in Belgian Hare (~150) and the lowest in Italian Silver (~106). The average length of ROH ranged from 4.001 ± 0.556 Mb in Italian White to 6.268 ± 1.355 Mb in Ermine. The same two breeds had the lowest (427.9 ± 86.4 Mb, Italian White) and the highest (921.3 ± 179.8 Mb, Ermine) average values of the sum of all ROH segments. More fancy breeds had a higher level of genomic inbreeding (as defined by ROH) than meat breeds. Several ROH islands contain genes involved in body size, body length, pigmentation processes, carcass traits, growth, and reproduction traits (e.g.: AOX1, GPX5, IFRD1, ITGB8, NELL1, NR3C1, OCA2, TRIB1, TRIB2). Genomic inbreeding parameters can be useful to overcome the lack of information in the management of rabbit genetic resources. ROH provided information to understand, to some extent, the genetic history of rabbit breeds and to identify signatures of selection in the rabbit genome
Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies
Objective: To systematically assess credibility and certainty of associations between cannabis, cannabinoids, and cannabis based medicines and human health, from observational studies and randomised controlled trials (RCTs).
Design: Umbrella review.
Data Sources: PubMed, PsychInfo, Embase, up to 9 February 2022. Eligibility criteria for selecting studies: Systematic reviews with meta-analyses of observational studies and RCTs that have reported on the efficacy and safety of cannabis, cannabinoids, or cannabis based medicines were included. Credibility was graded according to convincing, highly suggestive, suggestive, weak, or not significant (observational evidence), and by GRADE (Grading of Recommendations, Assessment, Development and Evaluations) (RCTs). Quality was assessed with AMSTAR 2 (A Measurement Tool to Assess Systematic Reviews 2). Sensitivity analyses were conducted.
Results: 101 meta-analyses were included (observational=50, RCTs=51) (AMSTAR 2 high 33, moderate 31, low 32, or critically low 5). From RCTs supported by high to moderate certainty, cannabis based medicines increased adverse events related to the central nervous system (equivalent odds ratio 2.84 (95% confidence interval 2.16 to 3.73)), psychological effects (3.07 (1.79 to 5.26)), and vision (3.00 (1.79 to 5.03)) in people with mixed conditions (GRADE=high), improved nausea/vomit, pain, spasticity, but increased psychiatric, gastrointestinal adverse event, and somnolence among others (GRADE=moderate). Cannabidiol improved 50% reduction of seizures (0.59 (0.38 to 0.92)) and seizure events (0.59 (0.36 to 0.96)) (GRADE=high), but increased pneumonia, gastrointestinal adverse events, and somnolence (GRADE=moderate). For chronic pain, cannabis based medicines or cannabinoids reduced pain by 30% (0.59 (0.37 to 0.93), GRADE=high), across different conditions (n=7), but increased psychological distress. For epilepsy, cannabidiol increased risk of diarrhoea (2.25 (1.33 to 3.81)), had no effect on sleep disruption (GRADE=high), reduced seizures across different populations and measures (n=7), improved global impression (n=2), quality of life, and increased risk of somnolence (GRADE=moderate). In the general population, cannabis worsened positive psychotic symptoms (5.21 (3.36 to 8.01)) and total psychiatric symptoms (7.49 (5.31 to 10.42)) (GRADE=high), negative psychotic symptoms, and cognition (n=11) (GRADE=moderate). In healthy people, cannabinoids improved pain threshold (0.74 (0.59 to 0.91)), unpleasantness (0.60 (0.41 to 0.88)) (GRADE=high). For inflammatory bowel disease, cannabinoids improved quality of life (0.34 (0.22 to 0.53) (GRADE=high). For multiple sclerosis, cannabinoids improved spasticity, pain, but increased risk of dizziness, dry mouth, nausea, somnolence (GRADE=moderate). For cancer, cannabinoids improved sleep disruption, but had gastrointestinal adverse events (n=2) (GRADE=moderate). Cannabis based medicines, cannabis, and cannabinoids resulted in poor tolerability across various conditions (GRADE=moderate). Evidence was convincing from observational studies (main and sensitivity analyses); in pregnant women, small for gestational age (1.61 (1.41 to 1.83)), low birth weight (1.43 (1.27 to 1.62)); in drivers, car crash (1.27 (1.21 to 1.34)); and in the general population, psychosis (1.71 (1.47 to 2.00)). Harmful effects were noted for additional neonatal outcomes, outcomes related to car crash, outcomes in the general population including psychotic symptoms, suicide attempt, depression, and mania, and impaired cognition in healthy cannabis users (all suggestive to highly suggestive).
Conclusions: Convincing or converging evidence supports avoidance of cannabis during adolescence and early adulthood, in people prone to or with mental health disorders, in pregnancy and before and while driving. Cannabidiol is effective in people with epilepsy. Cannabis based medicines are effective in people with multiple sclerosis, chronic pain, inflammatory bowel disease, and in palliative medicine, but not without adverse events
Describing variability in pig genes involved in coronavirus infections for a One Health perspective in conservation of animal genetic resources
Coronaviruses silently circulate in human and animal populations, causing mild to severe diseases.
Therefore, livestock are important components of a ?One Health? perspective aimed to control
these viral infections. However, at present there is no example that considers pig genetic resources
in this context. In this study, we investigated the variability of four genes (ACE2, ANPEP and DPP4
encoding for host receptors of the viral spike proteins and TMPRSS2 encoding for a host proteinase)
in 23 European (19 autochthonous and three commercial breeds and one wild boar population) and
two Asian Sus scrofa populations. A total of 2229 variants were identifed in the four candidate genes:
26% of them were not previously described; 29 variants afected the protein sequence and might
potentially interact with the infection mechanisms. The results coming from this work are a frst
step towards a ?One Health? perspective that should consider conservation programs of pig genetic
resources with twofold objectives: (i) genetic resources could be reservoirs of host gene variability
useful to design selection programs to increase resistance to coronaviruses; (ii) the describedFE1B-06B2-126F | Jos? Pedro Pinto de Ara?joN/
Acquiring shape and motion of interacting people from videos
In this thesis, we present a system for recovering the shape, the appearance and the motion of a scene where multiple people and objects interact with each other, using only passive and non-invasive techniques. The system, then, gives
a user the possibility to navigate inside such a representation and to replay the action from any point of view.In questa tesi, presenteremo un sistema per acquisire la forma, l'apparenza e il moto presenti all'interno di una scena nella quale più persone ed oggetti interagiscono tra loro, utilizzando solamente tecniche passive e non invasive. Il
sistema, dunque, fornisce all'utente la possibilità di navigare in questo tipo di rappresentazione e di riprodurre l'azione da un qualsiasi punto di vista
Multimodal 3D Shape Recovery from Texture, Silhouette and Shadow Information
Recent efforts attempt to combine together information of different passive methods. Critical issues in this research are the choice of data and how to combine such data in order to increase the overall information. The combination of stereo matching and silhouette information has recently received considerable attention both for obtaining high quality 3D models and for modelling 3D dynamic scenes. In this paper we present a 3D shape recovery system which fuse together silhouette, texture and shadow information. More precisely, we formulate the fusion problem of these three types of information. Experimental verification shows that the new method is capable to reconstruct a wider range of objects. 1
Common pole equalization of small rooms using a two-step real-time digital equalizer
Small enclosures are characterized by peculiar acoustical properties, which sometimes need to be corrected. Since the impulse responses taken in different positions of a small room exhibit common characteristics ascribing to the physical parameters of the enclosure-in particular some peaks in the low frequency spectra-an effective correction can be realized, making use of an equalizer which processes the music or speech signal during its travel along the reproduction chain. In this paper, an efficient yet versatile equalizer for small rooms, simple enough to run in real-time, is presented. It is based on the common acoustical poles model, focused on the low-frequency range and cascaded with a conditioning stage