397 research outputs found
Werkdruk en werkbeleving in een revalidatiecentrum. De toepassing van de Groninger Werkbeleving Screeningslijst, GWS.
The effect of HIV, behavioural change, and STD syndromic management on STD epidemiology in sub-Saharan Africa: simulations of Uganda
The effect of HIV, behavioural change, and STD syndromic management on STD epidemiology in sub-Saharan Africa: simulations of Uganda
Feasibility of controlling hookworm infection through preventive chemotherapy: a simulation study using the individual-based WORMSIM modelling framework
Background: Globally, hookworms infect 440 million people in developing countries. Especially children and women of childbearing age are at risk of developing anaemia as a result of infection. To control hookworm infection and disease (i.e. reduce the prevalence of medium and heavy infection to <1 %), the World Health Organization has set the target to provide annual or semi-annual preventive chemotherapy (PC) with albendazole (ALB) or mebendazole (MEB) to at least 75 % of all children and women of childbearing age in endemic areas by 2020. Here, we predict the feasibility of achieving <1 % prevalence of medium and heavy infection, based on simulations with an individual-based model. Methods: We developed WORMSIM, a new generalized individual-based modelling framework for transmission and control of helminths, and quantified it for hookworm transmission based on published data. We simulated the impact of standard and more intense PC strategies on trends in hookworm infection, and explored the potential additional impact of interventions that improve access to water, sanitation, and hygiene (WASH). The individual-based framework allowed us to take account of inter-individual heterogeneities in exposure and contribution to transmission of infection, as well as in participation in successive PC rounds. Results: We predict that in low and medium endemic areas, current PC strategies (including targeting of WCBA) will achieve control of hookworm infection (i.e. the parasitological target) within 2 years. In highly endemic areas, control can be achieved with semi-annual PC with ALB at 90 % coverage, combined with interventions that reduce host contributions to the environmental reservoir of infection by 50 %. More intense PC strategies (high frequency and coverage) can help speed up control of hookworm infection, and may be necessary in some extremely highly endemic settings, but are not a panacea against systematic non-participation to PC. Conclusions: Control of hookworm infection by 2020 is feasible with current PC strategies (including targeting of WCBA). In highly endemic areas, PC should be combined with health education and/or WASH interventions
''Nait Soezen, moar doun". Procesevaluatie van een project over generalistisch werkende wijkverpleegkundigen in Groningen en Hoogezand-Sappemeer
The effect of HIV, behavioural change, and STD syndromic management on STD epidemiology in sub-Saharan Africa: simulations of Uganda
An assessment was made of how the HIV epidemic may have influenced
sexually transmitted disease (STD) epidemiology in Uganda, and how HIV
would affect the effectiveness of syndromic STD treatment programmes
during different stages of the epidemic. The dynamic transmission model
STDSIM was used to simulate the spread of HIV and four bacterial and one
viral STD. Model parameters were quantified using demographic,
behavioural, and epidemiological data from rural Rakai and ot
Kwetsbare jongvolwassenen uit Beschermd Wonen & Opvang en participatie door middel van sport:Een kwalitatief onderzoek naar de factoren die een rol spelen in het al dan niet participeren aan de sportmomenten van #Clubsport
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