42 research outputs found

    Simulating Groups and the IntraGroup Medium: The Surprisingly Complex and Rich Middle Ground between Clusters and Galaxies

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    Galaxy groups are more than an intermediate scale between clusters and halos hosting individual galaxies, they are crucial laboratories capable of testing a range of astrophysics from how galaxies form and evolve to large scale structure (LSS) statistics for cosmology. Cosmological hydrodynamic simulations of groups on various scales offer an unparalleled testing ground for astrophysical theories. Widely used cosmological simulations with ∼(100 Mpc)3 volumes contain statistical samples of groups that provide important tests of galaxy evolution influenced by environmental processes. Larger volumes capable of reproducing LSS while following the redistribution of baryons by cooling and feedback are essential tools necessary to constrain cosmological parameters. Higher resolution simulations can currently model satellite interactions, the processing of cool (T ∼ 104 K) multi-phase gas, and non-thermal physics including turbulence, magnetic fields, and cosmic ray transport. We review simulation results regarding the gas and stellar contents of groups, cooling flows and the relation to the central galaxy, the formation and processing of multi-phase gas, satellite interactions with the intragroup medium, and the impact of groups for cosmological parameter estimation. Cosmological simulations provide evolutionarily consistent predictions of these observationally difficult-to-define objects, and have untapped potential to accurately model their gaseous, stellar, and dark matter distributions

    LoCuSS: Testing hydrostatic equilibrium in galaxy clusters

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    We test the assumption of hydrostatic equilibrium in an X-ray luminosity selected sample of 50 galaxy clusters at 0.15<z<0.30.15<z<0.3 from the Local Cluster Substructure Survey (LoCuSS). Our weak-lensing measurements of M500M_{500} control systematic biases to sub-4 per cent, and our hydrostatic measurements of the same achieve excellent agreement between XMM-Newton and Chandra. The mean ratio of X-ray to lensing mass for these 50 clusters is βX=0.95±0.05\beta_{\rm X}=0.95\pm0.05, and for the 44 clusters also detected by Planck, the mean ratio of Planck mass estimate to LoCuSS lensing mass is βP=0.95±0.04\beta_{\rm P}=0.95\pm0.04. Based on a careful like-for-like analysis, we find that LoCuSS, the Canadian Cluster Comparison Project (CCCP), and Weighing the Giants (WtG) agree on βP≃0.9−0.95\beta_{\rm P}\simeq0.9-0.95 at 0.15<z<0.30.15<z<0.3. This small level of hydrostatic bias disagrees at ∼5σ\sim5\sigma with the level required to reconcile Planck cosmology results from the cosmic microwave background and galaxy cluster counts

    The retroviral oncoprotein Tax targets the coiled-coil centrosomal protein TAX1BP2 to induce centrosome overduplication

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    Emerging evidence suggests that supernumerary centrosomes drive genome instability and oncogenesis. Human T-cell leukaemia virus type I (HTLV-I) is etiologically associated with adult T-cell leukaemia (ATL). ATL cells are aneuploid, but the causes of aneuploidy are incompletely understood. Here, we show that centrosome amplification is frequent in HTLV-I-transformed cells and that this phenotype is caused by the viral Tax oncoprotein. We also show that the fraction of Tax protein that localizes to centrosomes interacts with TAX1BP2, a novel centrosomal protein composed almost entirely of coiled-coil domains. Overexpression of TAX1BP2 inhibited centrosome duplication, whereas depletion of TAX1BP2 by RNAi resulted in centrosome hyperamplification. Our findings suggest that the HTLV-I Tax oncoprotein targets TAX1BP2 causing genomic instability and aneuploidy. © 2006 Nature Publishing Group.postprin

    ALMS1 and Alström syndrome: a recessive form of metabolic, neurosensory and cardiac deficits

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    Role of environment and mergers

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    Large scale structure and cosmolog

    J. Cell Biol.

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    Evidence for glaciation in the Northern Hemisphere back to 44 Ma from ice-rafted debris in the Greenland Sea

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    The widely accepted age estimate for the onset of glaciation in the Northern Hemisphere ranges between 2 and 15 million years ago (Ma). However, recent studies indicate the date for glacial onset may be significantly older. We report the presence of ice-rafted debris (IRD) in ∼44 to 30 Ma sediments from the Greenland Sea, evidence for glaciation in the North Atlantic during the Middle Eocene to Early Oligocene. Detailed sedimentological evidence indicates that glaciers extended to sea level in the region, allowing icebergs to be produced. IRD may have been sourced from tidewater glaciers, small ice caps, and/or a continental ice sheet
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