C-reactive protein as a disease activity marker in rheumatoid arthritis

Introduction: CRP is a valuable marker and regulator of systemic inflammation in RA that also appears to play a direct role in bone destruction and radiographic progression. CRP has also been implicated in the etiology of common comorbidities associated with RA. Decreasing CRP levels with RA treatment may contribute to reductions in disease activity, although beneficial effects of RA treatment seem to occur irrespective of CRP values. Aim: The purpose of this study was to examine whether levels of C-reactive protein (CRP), a sensitive marker of disease activity in rheumatoid arthritis (RA). Materials & methods: This study was carried out on 39 RF Positive patients from both sexes male and female from different age group at NIMS Super-Specialty Hospital, Sobha Nagar, Jaipur, Rajasthan. Inflammatory markers were performed in the laboratory. Results: In the current study, the majority of Rheumatoid Arthritis patients  belong to the age group of 41 to 60 (58.97%) and  male to female ration were 1:2. C - reactive protein found highly significant positive correlation. Out of total Rheumatoid Arthritis patients, 7.69% patients have normal C - reactive protein level and 92.30% have highly increased CRP level.

Risk of diabetes among patients with osteoarthritis

Research Background: Diabetes mellitus (DM) and osteoarthritis (OA) are common diseases that are predicted to increase in prevalence in the US and worldwide. Although a higher prevalence of osteoarthritis (OA) has been reported among diabetes mellitus (DM) patients, discrepancy and limitations of observational studies have precluded a decisive association. Objective: The objective of this study was to investigate the relationship between osteoarthritis (OA) and the incidence of diabetes mellitus (DM).  Methods: Study were conducted on Osteoarthritis subjects from both sex’s male and female from different age group during January 2020 to January 2022, at NIMS Super specialty Hospital Shobha Nagar,Jaipur (Rajasthan) India. OA of areas were finding out using the American College of Rheumatology classification criteria. Sociodemographic characteristics, health-related behaviors, comorbidities and DM clinical manifestations and laboratory parameters were determined. Result:  We were included 90 osteoarthritis patients in this study from both sex’s males (53.33%) and females (46.66%).&nbsp