3′UTR-located ALU Elements: Donors of Potetial miRNA Target Sites and Mediators of Network miRNA-based Regulatory Interactions

Recent research data reveal complex, network-based interactions between mobile elements and regulatory systems of eukaryotic cells. In this article, we focus on regulatory interactions between Alu elements and micro RNAs (miRNAs). Our results show that the majority of the Alu sequences inserted in 3′UTRs of analyzed human genes carry strong potential target sites for at least 53 different miRNAs. Thus, 3′UTR-located Alu elements may play the role of mobile regulatory modules that supply binding sites for miRNA regulation. Their abundance and ability to distribute a set of certain miRNA target sites may have an important role in establishment, extension, network organization, and, as we suppose – in the regulation and environment-dependent activation/inactivation of some elements of the miRNA regulatory system, as well as for a larger scale RNA-based regulatory interactions. The Alu-miRNA connection may be crucial especially for the primate/human evolution

MicroInspector: a web tool for detection of miRNA binding sites in an RNA sequence

Regulation of post-transcriptional gene expression by microRNAs (miRNA) has so far been validated for only a few mRNA targets. Based on the large number of miRNA genes and the possibility that one miRNA might influence gene expression of several targets simultaneously, the quantity of ribo-regulated genes is expected to be much higher. Here, we describe the web tool MicroInspector that will analyse a user-defined RNA sequence, which is typically an mRNA or a part of an mRNA, for the occurrence of binding sites for known and registered miRNAs. The program allows variation of temperature, the setting of energy values as well as the selection of different miRNA databases to identify miRNA-binding sites of different strength. MicroInspector could spot the correct sites for miRNA-interaction in known target mRNAs. Using other mRNAs, for which such an interaction has not yet been described, we discovered frequently potential miRNA binding sites of similar quality, which can now be analysed experimentally. The MicroInspector program is easy to use and does not require specific computer skills. The service can be accessed via the MicroInspector web server at

JORDANIAN ZEOLITIC TUFF AS A RAW MATERIAL FOR THE PREPARATION OF SUBSTRATES USED FOR PLANT GROWTH

One of the problems faced in front of industry for potting media is limited amount of quality row materials (mainly peat) for unlimited production of quality substrates in the future. The using of natural minerals for production of substrates or as amendments for existing substrates is possible solution for this problem. The natural zeolites with their specific properties – high CEC, high content of macro and microelements are one of good alternatives to the traditional potting media. Each zeolite deposit has unique chemical composition, physical and mechanical properties. That is why obligatory preliminary condition for their successful application in agriculture is caring out of biological study with agricultural plants for determination of the optimal parameters of chemical and physicochemical properties of the substrates

JORDANIAN ZEOLITIC TUFF AS A RAW MATERIAL FOR THE PREPARATION OF SUBSTRATES USED FOR PLANT GROWTH

One of the problems faced in front of industry for potting media is limited amount of quality row materials (mainly peat) for unlimited production of quality substrates in the future. The using of natural minerals for production of substrates or as amendments for existing substrates is possible solution for this problem. The natural zeolites with their specific properties – high CEC, high content of macro and microelements are one of good alternatives to the traditional potting media. Each zeolite deposit has unique chemical composition, physical and mechanical properties. That is why obligatory preliminary condition for their successful application in agriculture is caring out of biological study with agricultural plants for determination of the optimal parameters of chemical and physicochemical properties of the substrates

Evidence for coexistence of spin-glass and ferrimagnetic phases in BaFe12O19 due to basal plane freezing

We present here the results of low-temperature magnetization and X-ray magnetic circular dichroism studies on single crystals of BaFe12O19 which reveal for the first time the emergence of a spin glass phase, in coexistence with the long-range ordered ferrimagnetic phase, due to the freezing of the basal plane spin component.Comment: 4 pages, 4 figure

Evidence for Conical Magnetic Structure in M-type BaFe12O19 Hexaferrite: A Combined Single-Crystal XMCD and Neutron Diffraction Study

The magnetic ground state of BaFe12O19 (BFO) was investigated using X-ray absorption at 1.2 K and 1.5 K, respectively. The XMCD measurements on single-crystals of BFO in grazing incidence geometry reveal the canting of the spins away from the c-axis of the hexagonal unit cell. Single-crystal neutron diffraction studies reveal magnetic satellite peaks along the 00l reciprocal lattice row around the forbidden l = 2n +/- 1 positions confirming conical-type magnetic structure in the ground state of BFO. The observation of the conical magnetic structure of BFO opens the possibility of type-II multiferroicity in undoped BFO also.Comment: 15 pages, 4 figure

JORDANIAN ZEOLITIC TUFF AS A RAW MATERIAL FOR THE PREPARATION OF SUBSTRATES USED FOR PLANT GROWTH

One of the problems faced in front of industry for potting media is limited amount of quality row materials (mainly peat) for unlimited production of quality substrates in the future. The using of natural minerals for production of substrates or as amendments for existing substrates is possible solution for this problem. The natural zeolites with their specific properties – high CEC, high content of macro and microelements are one of good alternatives to the traditional potting media. Each zeolite deposit has unique chemical composition, physical and mechanical properties. That is why obligatory preliminary condition for their successful application in agriculture is caring out of biological study with agricultural plants for determination of the optimal parameters of chemical and physicochemical properties of the substrates