Investigating the Role of Social Return on the Understanding of Craft Brewery Visitors in British Columbia, Canada

Contributing to the Conference Theme: The role of social media in the development of Canada as a destination has been widely discussed locally, regionally, provincially, and federally. This research examines the role of using social media using a newly developed mechanism by which to consider how the use of social media relates to social involvement, memories, loyalty, place attachment, and authenticity. The context for this research is craft brewery tourism, one of the fastest growing aspects of tourism in many provinces. This abstract directly relates to multiple themes and sub-themes of the conference, including “Visitor experience design and measurement,” “Marketing and place promotion strategies and techniques,” and “Consumer demand for authentic places and experiences.

Death following bilateral complete Achilles tendon rupture in a patient on fluoroquinolone therapy: a case report

<p>Abstract</p> <p>Introduction</p> <p>Risk of tendon rupture, especially of the Achilles tendon, is one of the many potential side-effects of fluoroquinolone therapy. Achilles tendon rupture may be painful, debilitating or, as seen in our patient, devastating. While fluoroquinolone-induced tendon rupture typically accompanies other comorbidities (for example renal impairment) or concurrent steroid therapy, our case represents a medical 'first' in that there were no such comorbidities and no steroid therapy. Furthermore, our case is remarkable in that tendon rupture was bilateral, complete, and resulted in a devastating outcome.</p> <p>Case presentation</p> <p>A healthy 91-year-old Caucasian man was placed on fluoroquinolone (levofloxacin) therapy for a presumed bacterial pneumonitis. Subsequently, he developed bilateral heel pain, edema, and ecchymoses leading to a diagnosis of bilateral complete Achilles tendon rupture. This drug's side-effect was directly responsible for his subsequent physical and psychologic decline and unfortunate death.</p> <p>Conclusion</p> <p>Fluoroquinolones are a powerful and potent tool in the fight against bacterial infection. As a class, they are employed by primary care physicians as well as by subspecialty physicians in all areas of medical practice. However, as this case illustrates, the use of these drugs is not without risk. Attention must be paid to potential side-effects when prescribing any medication, and close follow-up with patients is a medical necessity to evaluate for these adverse reactions, especially with fluoroquinolones.</p

Understanding the Impacts of Festivals on Resident Attendees Before and During COVID-19: A First Look at the Vancouver Queer Film Festival

Although festivals and events have been identified as a growth segment within tourism, smaller cultural festivals have received much less attention. These smaller cultural festivals aim to bring cultural contributions and increased well-being to attendees and the host community in addition to their economic value. More specifically, queer film festivals have increased in number and size within the last decade and have an important history and purpose within the LGBT2Q+ community. As such, the current study investigated the attendees of the 2019 & 2020 Vancouver Queer Film Festival (VQFF), Western Canada’s largest queer film festival. The survey instrument asked attendees questions about subjective well-being, cultural/educational impacts, community benefits, future programming, and demographics. Preliminary results comparing demographic, behavioural, perceived benefit, and outcome characteristics between the 2019 in-person version and the 2020 virtual pandemic version of VQFF are discussed. Industry and academic implications and areas for future study are also considered

Programming biological models in Python using PySB

Mathematical equations are fundamental to modeling biological networks, but as networks get large and revisions frequent, it becomes difficult to manage equations directly or to combine previously developed models. Multiple simultaneous efforts to create graphical standards, rule-based languages, and integrated software workbenches aim to simplify biological modeling but none fully meets the need for transparent, extensible, and reusable models. In this paper we describe PySB, an approach in which models are not only created using programs, they are programs. PySB draws on programmatic modeling concepts from little b and ProMot, the rule-based languages BioNetGen and Kappa and the growing library of Python numerical tools. Central to PySB is a library of macros encoding familiar biochemical actions such as binding, catalysis, and polymerization, making it possible to use a high-level, action-oriented vocabulary to construct detailed models. As Python programs, PySB models leverage tools and practices from the open-source software community, substantially advancing our ability to distribute and manage the work of testing biochemical hypotheses. We illustrate these ideas using new and previously published models of apoptosis

Monitoring the Future national survey results on drug use, 1975-2019: Volume I, Secondary school students

http://deepblue.lib.umich.edu/bitstream/2027.42/162578/4/license_rdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/162578/1/Vol 1 2019 FINAL (original).pdfSEL

Monitoring the Future national survey results on drug use, 1975-2019: Overview, key findings on adolescent drug use

http://deepblue.lib.umich.edu/bitstream/2027.42/162579/1/FINAL.pdfSEL

Monitoring the Future national survey results on drug use, 1975-2019: Volume II, college students and adults ages 19-60

http://deepblue.lib.umich.edu/bitstream/2027.42/162576/1/2019-20 VOL II FINAL 3.pdfSEL

Demographic subgroup trends among adolescents in the use of various licit and illicit drugs, 1975-2019 (Monitoring the Future Occasional Paper No. 94)

http://deepblue.lib.umich.edu/bitstream/2027.42/162581/1/mtf-occ94.pdfSEL