2,643 research outputs found

    Modélisation physique de l'interaction entre obstacles et avalanches de neige poudreuse

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    International audienceIn order to better understand the interaction between powder snow avalanches and defence structures, we carried out physical experiments on small-scale models. The powder snow avalanche was simulated by a heavy salt solution in a water tank. Quasi two-dimensional and three-dimensional experiments were carried out with different catching dam heights. For the reference avalanche, the velocity just behind the nose in the head was greater than the front velocity. For the 2-D configuration, the ratio Umax/Ufront was as high as 1.6, but it depends on the height. For the 3-D configuration, this ratio differed slightly and was even greater (up to 1.8). The vertical velocity rose to 106% of the front velocity for the 3-D simulation and 74% for the 2-D simulation. The reduction in front velocity due to the presence of dams was an increasing function of the dam height. But this reduction depended on topography: dams were more effective on an open slope avalanche (3-D configuration). The ratio Umax/Ufront was an increasing function of the dam's height and reached a value of 1.9. The obstacle led to a reduction in vertical velocity downstream of the vortex zone

    Novel Molecular Targets in the Search for Anti-Inflammatory Agents

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    In the chronic state of inflammatory diseases, cellular signaling networks aimed at combating invading pathogens are often constitutively active and transmit their signals even in the absence of inflammatory agents. Thus, many anti-inflammatory drugs interfere with these dys- and hyperactivated cellular signaling networks or transcription factors. As many signaling molecules fulfill important and essential functions in normal cell physiology, their systemic and long-term inhibition may lead to severe side effects including an impaired immune response. To circumvent these pitfalls, two possibilities are proposed and discussed here: (I) Since many inflammatory diseases such as rheumatoid arthritis or inflammatory bowel disease are restricted to certain cell types or tissues, a new generation of anti-inflammatory drugs would target enzymes that are only operational in these affected tissues. (II) As some signaling pathways affect solely a small subset of inflammatory target genes, their inhibition bears the potential of limiting potential side effect

    Exciton lifetime in InAs/GaAs quantum dot molecules

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    The exciton lifetimes T1T_1 in arrays of InAs/GaAs vertically coupled quantum dot pairs have been measured by time-resolved photoluminescence. A considerable reduction of T1T_1 by up to a factor of ∌\sim 2 has been observed as compared to a quantum dots reference, reflecting the inter-dot coherence. Increase of the molecular coupling strength leads to a systematic decrease of T1T_1 with decreasing barrier width, as for wide barriers a fraction of structures shows reduced coupling while for narrow barriers all molecules appear to be well coupled. The coherent excitons in the molecules gain the oscillator strength of the excitons in the two separate quantum dots halving the exciton lifetime. This superradiance effect contributes to the previously observed increase of the homogeneous exciton linewidth, but is weaker than the reduction of T2T_2. This shows that as compared to the quantum dots reference pure dephasing becomes increasingly important for the molecules

    Optical Spectroscopy of IRAS 02091+6333

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    We present a detailed spectroscopic investigation, spanning four winters, of the asymptotic giant branch (AGB) star IRAS 02091+6333. Zijlstra & Weinberger (2002) found a giant wall of dust around this star and modelled this unique phenomenon. However their work suffered from the quality of the optical investigations of the central object. Our spectroscopic investigation allowed us to define the spectral type and the interstellar foreground extinction more precisely. Accurate multi band photometry was carried out. This provides us with the possibility to derive the physical parameters of the system. The measurements presented here suggest a weak irregular photometric variability of the target, while there is no evidence of a spectroscopic variability over the last four years.Comment: 5 pages, Latex, 3 tables, 4 figures, Astron. & Astrophys. - in pres

    Socio‐economic impact classification of alien taxa (SEICAT)

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    1 Many alien taxa are known to cause socio‐economic impacts by affecting the different constituents of human well‐being (security; material and non‐material assets; health; social, spiritual and cultural relations; freedom of choice and action). Attempts to quantify socio‐economic impacts in monetary terms are unlikely to provide a useful basis for evaluating and comparing impacts of alien taxa because they are notoriously difficult to measure and important aspects of human well‐being are ignored. 2 Here, we propose a novel standardised method for classifying alien taxa in terms of the magnitude of their impacts on human well‐being, based on the capability approach from welfare economics. The core characteristic of this approach is that it uses changes in peoples' activities as a common metric for evaluating impacts on well‐being. 2 Impacts are assigned to one of five levels, from Minimal Concern to Massive, according to semi‐quantitative scenarios that describe the severity of the impacts. Taxa are then classified according to the highest level of deleterious impact that they have been recorded to cause on any constituent of human well‐being. The scheme also includes categories for taxa that are not evaluated, have no alien population, or are data deficient, and a method for assigning uncertainty to all the classifications. To demonstrate the utility of the system, we classified impacts of amphibians globally. These showed a variety of impacts on human well‐being, with the cane toad (Rhinella marina) scoring Major impacts. For most species, however, no studies reporting impacts on human well‐being were found, i.e. these species were data deficient. 2 The classification provides a consistent procedure for translating the broad range of measures and types of impact into ranked levels of socio‐economic impact, assigns alien taxa on the basis of the best available evidence of their documented deleterious impacts, and is applicable across taxa and at a range of spatial scales. The system was designed to align closely with the Environmental Impact Classification for Alien Taxa (EICAT) and the Red List, both of which have been adopted by the International Union of Nature Conservation (IUCN), and could therefore be readily integrated into international practices and policies

    A vision for global monitoring of biological invasions

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    Managing biological invasions relies on good global coverage of species distributions. Accurate information on alien species distributions, obtained from international policy and cross-border co-operation, is required to evaluate trans-boundary and trading partnership risks. However, a standardized approach for systematically monitoring alien species and tracking biological invasions is still lacking. This Perspective presents a vision for global observation and monitoring of biological invasions. We show how the architecture for tracking biological invasions is provided by a minimum information set of Essential Variables, global collaboration on data sharing and infrastructure, and strategic contributions by countries. We show how this novel, synthetic approach to an observation system for alien species provides a tangible and attainable solution to delivering the information needed to slow the rate of new incursions and reduce the impacts of invaders. We identify three Essential Variables for Invasion Monitoring; alien species occurrence, species alien status and alien species impact. We outline how delivery of this minimum information set by joint, complementary contributions from countries and global community initiatives is possible. Country contributions are made feasible using a modular approach where all countries are able to participate and strategically build their contributions to a global information set over time. The vision we outline will deliver wide-ranging benefits to countries and international efforts to slow the rate of biological invasions and minimize their environmental impacts. These benefits will accrue over time as global coverage and information on alien species increases
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