Hepatic artery thrombosis after pediatric liver transplantation a medical or surgical event

Hepatic artery thrombosis (HAT) is one of the most serious complications after orthotopic liver transplan¬tation, and is associated with a high morbidity and mor¬tality. This study retrospectively reviewed 66 liver transplants in children under the age of 10 years during1 a year-long period at a single institution.;A, total of 28 perioperative variables were analyzed to identify responsible factors of HAT. Of the 66 children, 18 (26%) developed HAT within 15 days after the transplant (HAT group); 29 (42%) had an uneventful postoperative course (control group). To avoid the possible influence of other complications 19 patients were excluded. Of the variables compared between the 2 study groups, three surgical factors (diameter of the hepatic artery-- greater or less than 3 mm; type of arterial anastomosis—end-to-end versus the use of an iliac graft or aortic conduit; and number of times the anastomosis was redone--one versus more than one), were found to be significantly different (P<.05) between HAT and control groups. Two medical factors also were significantly different: the use of intraoperative transfusion of fresh frozen plasma (FFP) and the administration of postoperative prophylactic anticoagulant treatment. A heparin and dextran-40 protocol appeared to be effective in preventing HAT (P<.02). Moreover, after multivariate analysis, anticoagulation therapy was demonstrated to with poor hepatic artery flow. © 1989 by The Williams and Wilkins Co

Degradation of Mononitrotoluene by Electrochemical Method

Present paper deals with studies on the degradation of Mononitrotoluene (MNT) by electrochemical method. The Electro-Fenton and Electro-Peroxide methods are explored to degrade MNT upto its drain discharge limit of 1 ppm. Effects of some important parameters which ultimately decide the rate of degradation of MNT viz. oxidizer, pH, catalyst and voltage etc. have been critically studied. The detailed studies have been carried out which includes variation in different parameters viz. pH from acidic range to basic range, catalyst concentration from 10 ppm to 50 ppm, Oxidizer concentration from 5 mM to 40 mM and potential across electrodes from 4 V to 24 V for efficient degradation of MNT. It is observed that optimised values of precursors viz. catalyst (FeSO4 ) concentration of 40 ppm, pH of 3, potential across electrodes of 12V and oxidizer (H2 O2 ) concentration of 25 mM; Electro-Fenton reaction has been carried out to degrade 50 ppm MNT solution up to its drain discharge limit of 1 ppm and on other hand under Electro-Peroxide reaction results in degradation of MNT from 50 ppm to 12 ppm. The comparative studies of Electro-Fenton and Electro-Peroxide reactions have been carried out for MNT solution and the treated solution has been characterised by using UV-Visible spectrophotometer and Total Organic Carbon (TOC) analyzer and the obtained data on MNT effluent studies may be applicable to explore the efficient mineralisation of 2-Methyl-1, 3, 5-trinitrobenzene effluent. The observed results have been interpreted and reported in the present study

Soil Fertility Atlas for Karnataka, India

Our research during the last decade showed that soil testing is an effective tool for diagnosing nutrient problems in farmers' fields. Soil test-based nutrient management allows a judicious use of fertilizers supplying various nutrient elements. This Atlas comprises of results from Bhoochetan Mission Project Under which a large-scale sampling was undertaken on farmers' fields in all the district of Karnataka. Bhoochetana is a mission project for enchancing agricultural productivity of rain-fed systems in the state of Karnataka by adopting science-led approach with technical backstopping from ICRISAT-led consortium. The recommendations on nutrient applications are made by using critical limits in the soil for major, secondary and micronutrients. The soil test results are categorised as sufficient (Soil test value above the critical limit of an element) or deficient (Soil test value below the critical limit)

Statistical Data Analysis in Emergency Management Elements of Indian State of Tamil Nadu Manufacturing Industries Utilising LPG

Introduction: Process safety is becoming more difficult as requirements increase. When balancing quality, volume, and safety on a budget, major accidents are unavoidable. The inability of organizations to absorb unwelcome and unanticipated disruptions is a major contributor to complacency and a decline in safety attitudes. The inability of industries to interpret standards impedes self-regulation. Methods: A total of 50 emergency management element questionnaires were developed to evaluate the state of an industry. These questionnaires were categorized as first aid, personal protective equipment (PPE), communication systems used in plants, safety education and training, occupational hygiene and health, management systems on accident reporting, safety and health, analysis and investigation, and procedures and protocols. From 32 LPG industries in Tamil Nadu districts, information for all 50 questions was gathered and the statistical tool "Analysis ToolPak" in Excel 2010 was used to analyze the data. Results: This study conducted a comprehensive statistical analysis of various aspects of industrial on-site emergency planning. The questionnaire's reliability was determined using Cronbach's alpha test. Utilizing descriptive statistics, t-tests for means, one-way ANOVA, and histograms, statistical evaluation was conducted. Encouragingly, all the results were favorable, providing compelling evidence that the LPG-utilizing industries in various regions of Tamil Nadu, India, are exceeding safety requirements. Conclusion: In conclusion, the findings suggest that improved legal frameworks, laws, and implementation of EME in communication systems can greatly enhance the development of safety in plants, fire protection, and emergency health services. These measures can significantly reduce the occurrence of accidents and improve the response time to emergencies, ultimately saving lives and reducing property damage

Diagnostic accuracy of a clinical diagnosis of idiopathic pulmonary fibrosis: An international case-cohort study

We conducted an international study of idiopathic pulmonary fibrosis (IPF) diagnosis among a large group of physicians and compared their diagnostic performance to a panel of IPF experts. A total of 1141 respiratory physicians and 34 IPF experts participated. Participants evaluated 60 cases of interstitial lung disease (ILD) without interdisciplinary consultation. Diagnostic agreement was measured using the weighted kappa coefficient (\u3baw). Prognostic discrimination between IPF and other ILDs was used to validate diagnostic accuracy for first-choice diagnoses of IPF and were compared using the Cindex. A total of 404 physicians completed the study. Agreement for IPF diagnosis was higher among expert physicians (\u3baw=0.65, IQR 0.53-0.72, p20 years of experience (C-index=0.72, IQR 0.0-0.73, p=0.229) and non-university hospital physicians with more than 20 years of experience, attending weekly MDT meetings (C-index=0.72, IQR 0.70-0.72, p=0.052), did not differ significantly (p=0.229 and p=0.052 respectively) from the expert panel (C-index=0.74 IQR 0.72-0.75). Experienced respiratory physicians at university-based institutions diagnose IPF with similar prognostic accuracy to IPF experts. Regular MDT meeting attendance improves the prognostic accuracy of experienced non-university practitioners to levels achieved by IPF experts

Design and Performance Evaluation of Modular Compliant Mechanisms

In this study, modular design for compliant stage using a parallelogram flexure module is proposed. The material of the proposed stages chosen is Aluminium alloy T6-6051 due to excellent phase stability, low internal stresses, low density etc. The stage is driven by a linear electromagnetic actuator i.e. voice coil actuator. The preliminary static structural analysis is used to determine the range of motion, stiffness by considering stress limitations. FEA results show a maximum range of motion up to 30mm without exceeding stress limit of 275 Mpa. The proposed mechanisms provide low stiffness in the degree of freedom directions and provide large stiffness in the degree of constraint direction.so it is adequately constrained. The stage provides high precision and repeatability with an increased range of motion, minimal parasitic motions (i.e.150 microns) and limited cross axes coupling

Changes in protein composition and protein phosphorylation during somatic embryogenesis and plant regeneration in peanut (Arachis hypogaea L.)

Changes in protein profiles and protein phosphorylation were studied in various stages of germinating somatic and zygotic embryos. Many proteins, which were expressed in cotyledonary stage somatic embryos, were also present in the zygotic embryos obtained from mature dry seed. The intensity of 22 kDa protein was much higher in zygotic embryos in comparison to cotyledonary somatic embryos. Proteins of 55, 53, 27 and 25 kDa did not vary in expression during different stages of germination of somatic and zygotic embryos. There was rapid accumulation of 28 kda protein in germinating zygotic and somatic embryos at 3 rd stage and persisted during the subsequent stages of germination indicating the emergence of radical and plumule. A clear difference was observed in the patterns of protein phosphorylation in germinating somatic and zygotic embryos. A 50 kDa protein was heavily phosphorylated in mature zygotic embryos at 2nd stage of germination and disappeared in 3rd stage of germination. Protiens of 50 and 43 kDa proteins showed enhanced phosphorylation up to 3rd stage and drastic reduction was observed at 4th stage. In addition, phosphorylation of 68 and 65 kDa specifically appeared in 3rd stage of germinating somatic embryos and were not observed during any germinating stages of zygotic embryos