AGRHYMET: A drought monitoring and capacity building center in the West Africa Region

The AGRHYMET Regional Center, a specialized institution of the Permanent Interstates Committee for Drought Control in the Sahel (CILSS), was created in 1974 at the aftermaths of the severe droughts that affected this region in the early 1970s. The mission assigned to the Center was to train personnel, provide adequate equipment for the meteorological and hydrological stations networks, and set up regional and national multidisciplinary working groups to monitor the meteorological, hydrological, crops and pastures conditions during the rainy season. As such, it can be considered as the West Africa drought monitoring center, similarly to its younger counterparts in Eastern and Southern Africa. After 40 years of existence, AGRHYMET’s scope of activities expend now beyond the geographical boundaries of CILSS member states, to include the whole West Africa thanks to several initiatives it has been implementing on behalf of the Economic Commission of West African States (ECOWAS) on food security and environmental issues, including climate change. Throughout the years, AGRHYMET developed, in collaboration with international research organizations, models and methodologies based on ground and satellite observations to monitor rainfall, food crop water requirements satisfaction and prospective yields, the progress of vegetation front and its seasonal and interannual variations. It has trained about 1200 new experts in agrometeorology, hydrology, equipment maintenance, and plant protection, and more than 6000 professionals on topics related to food security, climate change, and sustainable natural resources (land and water) management. As of now, AGRHYMET staff is involved in several international initiatives on climate change, food security, and environmental monitoring that allow them keep abreast of the best available technologies and methods, and also contribute to generating knowledge on those issues

Risk Factors for Thrombosis in an African Population

Little is known about the biological, epidemiological, and clinical risk factors for thrombosis and venous thromboembolism (VTE) among Black Africans. We undertook a study of the prevalence of VTE risk factors for thrombosis in a Senegalese population. A three-year cross-sectional and case-control study involving 105 cases and 200 controls was conducted in various hospitals in Dakar (Senegal). Our results demonstrate that oral contraception, immobilization by casts, surgery, and blood group were significantly associated with VTE occurrence. Additionally, 16 cases and 2 controls had protein S (PS) values of less than 48.4% (M-2SD), exhibiting a highly significant difference ( P < 1 x 10 −4 ). The number of cases with a low protein C (PC) level was significantly higher than the respective number of controls. Using logistic regression methods, we established a correlation between significantly associated variables and deep venous thrombosis (DVT) occurrence. Age, obesity, sickle cell disease, and PC deficiency were not significantly associated with thrombosis. In contrast, gender, PS deficiency, varicose veins, surgery, non-O blood type, and the presence of anti-phospholipid antibodies were significantly and independently associated with DVT. These findings are extremely useful for clinical management of patients suffering from DVT and can help to reduce the high recurrence rate observed in our study

Hydroxychloroquine and Azithromycin Treatment of Hospitalized Patients Infected with SARS-CoV-2 in Senegal from March to October 2020

International audienceAs of today, little data is available on COVID-19 in African countries, where the case management relied mainly on a treatment by association between hydroxychloroquine (HCQ) and azithromycin (AZM). This study aimed to understand the main clinical outcomes of COVID-19 hospitalized patients in Senegal from March to October 20202. We described the clinical characteristics of patients and analysed clinical status (alive and discharged versus hospitalized or died) at 15 days after Isolation and Treatment Centres (ITC) admission among adult patients who received HCQ plus AZM and those who did not receive this combination. A total of 926 patients were included in this analysis. Six hundred seventy-four (674) (72.8%) patients received a combination of HCQ and AZM. Results showed that the proportion of patient discharge at D15 was significantly higher for patients receiving HCQ plus AZM (OR: 1.63, IC 95% (1.09–2.43)). Factors associated with a lower proportion of patients discharged alive were: age ≥ 60 years (OR: 0.55, IC 95% (0.36–0.83)), having of at least one pre-existing disorder (OR: 0.61, IC 95% (0.42–0.90)), and a high clinical risk at admission following NEWS score (OR: 0.49, IC 95% (0.28–0.83)). Few side effects were reported including 2 cases of cardiac rhythmic disorders in the HCQ and AZM group versus 13 in without HCQ + AZM. An improvement of clinical status at 15 days was found for patients exposed to HCQ plus AZM combinatio

Niakhar, mémoires et perspectives

Fondé en 1962 en zone rurale à 150 km de Dakar, en pays Sereer, l'observatoire de Niakhar est le plus ancien observatoire de population en Afrique encore en activité. Au cœur d'une histoire scientifique et humaine originale, il a permis d'assurer, depuis sa création, le suivi sanitaire, démographique, social, économique et environnemental de plus de deux générations. Les résultats de recherche de Niakhar, avec des indicateurs suivis dans le temps long, ont éclairé et accompagné les politiques nationales et internationales en matière de santé, notamment pour la prévention du paludisme. En revisitant 50 années de recherche sur le site de Niakhar, cet ouvrage décrit et analyse la construction de cette plate-forme d'observation prospective pluridisciplinaire. Il illustre l'intérêt de l'approche sur le long terme dans les différents domaines de recherche et ouvre une réflexion sur les enjeux éthiques particuliers à cet instrument de collecte. Enfin, il propose des pistes d'évolution méthodologique et de gouvernance pour la recherche. Cette première synthèse sur l'observatoire de Niakhar permettra à l'État sénégalais et aux décideurs ouest-africains, avec les institutions internationales et les scientifiques, de disposer de bases concrètes pour optimiser ces plates-formes de recherche et les mobiliser dans la perspective des objectifs de développement durable